Active Recombinant Human Interleukin 4 Induced 1, His-tagged
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Cat.No. : | IL4I1-654H Optional Service: Optional requirements on this protein |
Product Overview : | RecombinantHuman IL4I1 protein was expressed in Chinese HamsterOvary cell line. Gln22-His567, with a C-terminal 6-Histag. |
Description : | IL4I1 isencoded by a B-cell IL-4-inducible gene, FIG1, and is highly expressed inprimary metastinal B-cell lymphomas. It belongs to the flavin monoamineoxidase family, FIG1 subfamily. Enzymological characterization reveals that IL4I1has L-amino acid oxidase activity with preference toward aromatic aminoacids. Studies have shown that hIL-4I1 inhibited the proliferation ofCD3-stimulated T lymphocytes with a similar effect on CD4(+) and CD8(+) Tcells. Its inhibitory effect was dependent on enzymatic activity and H2O2 production.Its restricted expression to lymphoid tissues indicates that it may play animportant function in the immune system. |
Source : | Chinese HamsterOvary cell line, CHO-derived. |
Form : | Supplied as a 0.2 umfiltered solution in Tris, NaCl and Glycerol. |
N-terminalSequence : | Gln22 predicted. |
MolecularWeight : | 61 kDa |
Activity : | Measuredby its ability to oxidize phenylalanine in a horseradish peroxidase coupled assay.The specific activity is > 150 pmol/min/μg, as measured under the describedconditions. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 70-75kDa, reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use amanual defrost freezer and avoid repeated freezethaw cycles. 6 monthsfrom date of receipt, -20 to -70°C as supplied. 3 months,-20to-70°C under sterile conditions after opening. |
Gene Name : | IL4I1 interleukin 4 induced 1[ Homo sapiens ] |
Official Symbol : | IL4I1 |
Synonyms : | IL4I1; interleukin 4induced 1; LAO;FIG1; LAAO; L-amino-acidoxidase; Fig-1 protein; IL4-induced protein 1; interleukin four induced 1; EC1.4.3.2 |
Gene ID : | 259307 |
mRNA Refseq : | NM_172374 |
Protein Refseq : | NP_758962 |
MIM : | 609742 |
UniProt ID : | Q96RQ9 |
Chromosome Location : | 19q13.3-q13.4 |
Pathway : | Alanine, aspartate and glutamate metabolism;Cysteine and methionine metabolism; Metabolic pathways; Phenylalaninemetabolism; Phenylalanine; Tryptophan metabolism; Tyrosine metabolism; Valine,leucine and isoleucine degradation |
Function : | L-amino-acid oxidaseactivity; oxidoreductase activity |
◆ Recombinant Protein
IL4I1-2320H | Recombinant Human IL4I1 Protein, His-tagged | +Inquiry |
IL4I1-8173M | Recombinant Mouse IL4I1 Protein | +Inquiry |
Il4i1-639M | Active Recombinant Mouse Il4i1 protein, His-tagged | +Inquiry |
IL4I1-2613H | Recombinant Human IL4I1 protein, His-tagged | +Inquiry |
IL4I1-01H | Recombinant Human IL4I1 Protein, His-Tagged | +Inquiry |
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◆ Lysates
IL4I1-5225HCL | Recombinant Human IL4I1 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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