Active Recombinant Mouse Interleukin 4 Induced 1, His-tagged

• Cat.No.: Il4i1-653M
• Product Overview: RecombinantMouse Il4i1 protein was expressed in Chinese HamsterOvary cell line. Leu21-Ser630, with a C-terminal 6-His tag.

Specification

• Species: Mouse
• Source: CHO
• Tag: His
• Protein Length: 21-630 a.a.
• Description: Il4i1 wasfirst identified in mouse B cells as part of the response to IL-4, a keyregulator of the immune response. Later, the enzyme was shown to be a memberof the flavin-containing amino acid oxidase family and closely related toL-amino acid oxidases. Enzymological characterization reveals that Il4i1 hasL-amino acid oxidase activity with preference toward aromatic amino acids.Its limited expression in immune tissues, dendritic cells, and macrophagesindicates that it may play an importantfunction in the immune system.
• Form: Supplied as a 0.2 umfiltered solution in Sodium Acetate and NaCl.
• N-terminalSequence: Leu21
• MolecularWeight: 69 kDa
• Activity: Measuredby its ability to produce hydrogen peroxide during the oxidation of phenylalanine.The specific activity is > 100 pmol/min/μg, as measured under thedescribed conditions.
• Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
• SDS-PAGE: 86 kDa,reducing conditions.
• Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 6 monthsfrom date of receipt, -20 to -70°C as supplied. 3 months,-20to-70°C under sterile conditions after opening.

Gene Information

• Gene Name: Il4i1 interleukin 4 induced 1 [Mus musculus ]
• Official Symbol: Il4i1
• Synonyms: Il4i1; interleukin 4induced 1; LAO; Fig1; LAAO; Fig1-ps; L-amino-acidoxidase; protein Fig-1; IL4-induced protein 1; interleukin-4-induced protein1; interleukin-four induced gene 1; interleukin-four induced protein-1;interleukin-four induced gene-1 protein; EC 1.4.3.2
• Gene ID: 14204
• mRNA Refseq: NM_010215
• Protein Refseq: NP_034345
• UniProt ID: O09046
• Chromosome Location: 7
• Pathway: Alanine, aspartateand glutamate metabolism; CCysteine and methionine metabolismysteine andmethionine metabolism; Metabolic pathways; Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis; Tryptophan metabolism;Tyrosine metabolism; Valine, leucine and isoleucine degradation
• Function: L-amino-acid oxidaseactivity; oxidoreductase activity