• Official Full Name
  • integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
  • Background
  • This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • ITGA2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); CD49B; integrin alpha-2; CD49b; integrin alpha 2; collagen receptor; VLA-2 subunit alpha; platelet antigen Br; platelet glycoprotein Ia; platelet glycoprotein GPIa; CD49 antigen-like fam
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ITGA2 Protein, GST-tagged
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human ITGA2&ITGB1
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ITGA2 protein, His & S-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Itga2 protein, His & GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ITGA2 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ITGA2 Protein, His-tagged
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle ITGA2 protein, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human ITGA2 293 Cell Lysate
Source (Host):Species:
Product nameAnti-Human ITGA2 MAb Stable Cell Line-CHO
Source (Host):Species:
Product nameAnti-Human ITGA2 F(ab) Stable Cell Line-CHO
Source (Host):Species:
Product nameAnti-Human ITGA2 scFv Stable Cell Line-CHO

ITGA2 Related Articles

Vittal, R; Mickler, EA; et al. Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-beta and Associated Transcripts in Pulmonary Fibrosis. PLOS ONE 8:-(2013).
Ullah, M; Sittinger, M; et al. Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units. MATRIX BIOLOGY 32:452-465(2013).