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Recombinant Human ITGA2 protein, His & S-tagged

Cat.No. : ITGA2-5836H
Product Overview : Recombinant Human ITGA2 aa. (Pro170~Ile361 (Accession # P17301)) fused with N-terminal His & S tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : His & S
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 26.8kDa
Protein length : Pro170~Ile361 (Accession # P17301)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 5.7.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : ITGA2 integrin subunit alpha 2 [ Homo sapiens (human) ]
Official Symbol : ITGA2
Synonyms : BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; CD49 antigen-like family member B; alpha 2 subunit of VLA-2 receptor; collagen receptor; human platelet alloantigen system 5; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; integrin alpha-2
Gene ID : 3673
mRNA Refseq : NM_002203.3
Protein Refseq : NP_002194.2
UniProt ID : P17301

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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