MAPK12 Protein


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Official Full Name mitogen-activated protein kinase 12
Background Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
Synonyms MAPK12; mitogen-activated protein kinase 12; SAPK3; ERK6; p38gamma; PRKM12; SAPK 3; ERK-6; MAPK 12; MAP kinase 12; MAP kinase p38 gamma; stress-activated protein kinase 3; mitogen-activated protein kinase 3; extracellular signal-regulated kinase 6; mitoge
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK12-27H Recombinant Human MAPK12 protein, GST-tagged Insect Cell GST Inquiry
    Human MAPK12-1264H Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged Insect Cell His Inquiry
    Human MAPK12-1343H Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged E.coli His Inquiry
    Human MAPK12-169H Recombinant Human MAPK12 Protein, His-tagged E.coli His Inquiry
    Human MAPK12-264H Recombinant Human MAPK12, Gly & Pro tagged Insect Cell His Inquiry
    Human MAPK12-279H Recombinant Human MAPK12, His-GST tagged Insect Cell His Inquiry
    Human MAPK12-30H Recombinant human biotinylated MAPK12, His-tagged E.coli His Inquiry
    Human MAPK12-31377TH Recombinant Human MAPK12 N/A Inquiry
    Human MAPK12-375H Recombinant Human MAPK12, GST-tagged, Active Sf9 Insect Cell GST Inquiry
    Human MAPK12-738H Recombinant Human Mitogen-activated Protein Kinase 12 E.coli N/A Inquiry
    Mouse MAPK12-9528M Recombinant Mouse MAPK12 Protein Mammalian Cell His Inquiry
    Rat MAPK12-3572R Recombinant Rat MAPK12 Protein Mammalian Cell His Inquiry
    Human MAPK12-001HCL Recombinant Human MAPK12 cell lysate Insect Cell N/A Inquiry
    Human MAPK12-3014H Recombinant Human MAPK12 protein, GST-tagged E.coli GST Inquiry
    Human MAPK12-9248HF Recombinant Full Length Human MAPK12 Protein, GST-tagged E.coli GST Inquiry
    Human MAPK12-1340H Recombinant Human MAPK12 protein, His-tagged E. coli His Inquiry

    MAPK12 involved in several pathways and played different roles in them. We selected most pathways MAPK12 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway NFKB1; CACNB2; ATF4; CACNA2D3; MAPK8IP2; MAPK8IP3; FLNC; FGF13A; FGF6A; CACNA1SA
    Rap signaling pathway PARD6A; ITGAL; MLLT4; PLCB3; CDH1; NRAS; VASP; FGF17; BCAR1; AKT2
    FoxO signaling pathway PLK1; AKT1; SOD2; HRASB; IGF1RA; SLC2A4; SMAD4; GRB2B; PIK3R3B; INSB
    Sphingolipid signaling pathway RAC1; MAPK11; TRAF2; SPHK2; TNF; PPP2CA; SPTLC1; MAPK1; MAPK12; LASS4
    Oocyte meiosis IGF1; YWHABA; PPP2CB; CAMK2B1; PLK1; PPP3R2; MAD2L2; CPEB4; PRKACBB; BTRC
    Adrenergic signaling in cardiomyocytes CALML5; PPP2R3C; CACNA1DA; CACNB4; ATP1B1B; AKT2L; PLCB4; ADRB2B; PIK3CB; CALM1
    VEGF signaling pathway PLA2G4F; PPP3CCA; MAPK1; PTK2AA; PPP3R1B; MAPKAPK2A; SPHK2; MAPK3; PIK3R5; PIK3CA
    Osteoclast differentiation PPP3CA; SQSTM1; TNFRSF1A; PIK3CA; MAPK1; ACP5; TGFB1; FOS; CYBB; TYROBP
    Signaling pathways regulating pluripotency of stem cells FGFR1; SMAD3; GRB2; PIK3CA; SMAD1; AKT1; KRAS; ID1; LIF; INHBC
    Platelet activation TLN1; FGA; LCP2; SYK; FCER1G; MAPK3; MYLK2; P2RY1; GNAS; PRKG1
    Toll-like receptor signaling pathway FOS; IL12BA; PIK3CG; TLR5; IKBKB; IFNB; MAPK8; IFNA5; PIK3R3; SPP1
    NOD-like receptor signaling pathway NFKBIAB; NAIP7; NLRC4; NFKB1; CCL5; HSP90AA1.2; HSP90B1; IKBKG; NFKBIB; NFKBIA
    RIG-I-like receptor signaling pathway DDX3X; IFNPHI3; FADD; IL12BA; MAPK14B; OTUD5; TBK1; IFNK; IKBKE; IFNB
    T cell receptor signaling pathway IL5; KRAS; MAPK13; VAV2; NFKBIE; CD28; PDPK1; CARD11; MAPK1; MAPK3
    Fc epsilon RI signaling pathway PLA2G4D; PLA2G4A; MAP2K1; PIK3CA; IL5; AKT2; PLA2G4F; FCER1A; VAV3; MAP2K2
    TNF signaling pathway NFKB1; FADD; ITCH; MLKL; MAP3K5; TNFAIP3; CASP10; MAP2K4; IL15; CCL5
    Leukocyte transendothelial migration NCF1; Itgam&Itgb2; PIK3R2; ACTG1; CLDN15; CLDN8; MYL12B; MYL7; JAM3; RAP1A
    Neurotrophin signaling pathway MAPK13; CAMK2D; MAP2K5; RPS6KA1; IRAK2; MAP2K2; TP53; GSK3B; CAMK4; MAPK7
    Retrograde endocannabinoid signaling GABRB3; GABRA6; MAPK13; GABRB1; MAPK11; GRIA3; GABRA4; GNB1; GNGT2; GRIA1
    Dopaminergic synapse PPP2CA; KCNJ5; GNG7; CREB3; GNAI3; PPP1CA; PPP1CC; GNB4; MAPK9; GNG13
    Inflammatory mediator regulation of TRP channels PRKCH; PRKACB; PRKCA; PLCG1; PLCG2; HTR2B; SRC; PPP1CA; ITPR1; PIK3R3
    GnRH signaling pathway MAP2K3; RAF1; KRAS; CDC42; ITPR1; MAP2K6; MAPK8B; GNAS; MMP14; ATF4
    Progesterone-mediated oocyte maturation PPP1R2P9; CDC23; ADCY1A; GNAI3; CDC26; GNAI1; INS2; MAP2K1; CPEB1; MAD2L1
    Prolactin signaling pathway PRL; MAPK12; AKT2; NEK3; TH; MAPK11; GALT; PRP2; INS; LHCGR
    Amyotrophic lateral sclerosis (ALS) TP53; CCS; GRIN2A; NEFM; SLC1A2; TOMM40; MAPK13; MAP3K5; SOD1; GRIA1
    Epithelial cell signaling in Helicobacter pylori infection MAPK9; MAPK8; IL-8; NOD1; CXCL1; RELA; ATP6V0C; ATP6V1G1; ATP6V1G2; JAM3
    Shigellosis MAD2L2; ABL1; MAPK13; U2AF1; MAPK1; IKBKG; MAPK12; CDC42; ACTG1; ELMO1
    Salmonella infection MYD88; PFN4; IFNG1-2; TJP1; NOS2A; RHOG; PFN2L; CCL3; PLEKHM2; PKN1
    Pertussis C1R; GM5077; CXCL5; MAPK9; ITGB2L; MAPK1; CALML3; CASP7; LY96; CALM4
    Leishmaniasis Itgam&Itgb2; IL4; HLA-DMA; TGFB2; PTPN6; NCF4; MAPK13; FCGR3; IL12B; IFNGR1
    Chagas disease (American trypanosomiasis) MAPK1; TNFRSF1A; IKBKB; IL10; CALR; BDKRB2; FADD; MAPK10; CD3E; CD3D; TGFB1
    Toxoplasmosis LDLR; MAP3K7; HLA-DPB1; LAMB4; BIRC7; TGFB2; LAMA5; IRGM1; BIRC8; GNAO1
    Tuberculosis FCGR1; RIPK2; RFXANK; PPP3CB; LAMP2; CAMK2B; LBP; SPHK1; MAPK1; IL12A
    Hepatitis C IKBKB; STAT2; MAPK10; MAPK13; IFIT1; IFNA10; OAS1; MAPK12; MAPK1; BRAF
    Influenza A IFNAR1; OAS1A; HLA-DPA1; FDPS; IL1A; BLA; IL12A; H2-AB1; TMPRSS2; BLB1
    Epstein-Barr virus infection PSMC4; POLR3H; CSNK2A2; PIK3R1; MAPK9; HLA-DRB5; IRAK1; TBP; YWHAE; PSMC6
    Proteoglycans in cancer SRC; ITGA2; PTPN11; LUM; FZD6; DDX5; PLCG2; ITGA5; MRAS; PPP1R12A

    MAPK12 has several biochemical functions, for example, ATP binding, MAP kinase activity, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK12 itself. We selected most functions MAPK12 had, and list some proteins which have the same functions with MAPK12. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding MAGI3; KCNJ1; NADK2; NDUFA13; ATP1A1A.4; UCKL1A; RAD50; MCM3L; HIPK4; HSC70
    MAP kinase activity MAPK11; MAPK13; NLK1; MAPK12B; MAPK15; NLK; NLK2; MAPK14; MAPK12A; MAPK8B
    magnesium ion binding BPNT1; PKMB; PRPSAP1; PGP; PDXK; ATP11A; ATP8B3; NT5C1BA; PTEN; STK3
    protein binding TNPO2; KIAA0947; INTS4; OGG1; TMEM8B; FAF2; SOX9A; IL5RA; AIFM1; PCOLCE
    protein serine/threonine kinase activity RPS6KB2; cka1; MAPKAPK5; NLK2; MAP3K4; MAPK6; PIK3CG; LRRK2; PRKCZ; CDC7

    MAPK12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK12 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK12.


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