MAPK12 Protein


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Official Full Name mitogen-activated protein kinase 12
Background Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
Synonyms MAPK12; mitogen-activated protein kinase 12; SAPK3; ERK6; p38gamma; PRKM12; SAPK 3; ERK-6; MAPK 12; MAP kinase 12; MAP kinase p38 gamma; stress-activated protein kinase 3; mitogen-activated protein kinase 3; extracellular signal-regulated kinase 6; mitoge
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK12-27H Recombinant Human MAPK12 protein, GST-tagged Insect Cell GST
    Human MAPK12-1264H Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged Insect Cell His
    Human MAPK12-1343H Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged E.coli His
    Human MAPK12-169H Recombinant Human MAPK12 Protein, His-tagged E.coli His
    Human MAPK12-264H Recombinant Human MAPK12, Gly & Pro tagged Insect Cell His
    Human MAPK12-279H Recombinant Human MAPK12, His-GST tagged Insect Cell His
    Human MAPK12-30H Recombinant human biotinylated MAPK12, His-tagged E.coli His
    Human MAPK12-31377TH Recombinant Human MAPK12 N/A
    Human MAPK12-375H Recombinant Human MAPK12, GST-tagged, Active Sf9 Insect Cell GST
    Human MAPK12-738H Recombinant Human Mitogen-activated Protein Kinase 12 E.coli N/A
    Mouse MAPK12-9528M Recombinant Mouse MAPK12 Protein Mammalian Cell His
    Rat MAPK12-3572R Recombinant Rat MAPK12 Protein Mammalian Cell His
    Human MAPK12-001HCL Recombinant Human MAPK12 cell lysate Insect Cell N/A
    Human MAPK12-3014H Recombinant Human MAPK12 protein, GST-tagged E.coli GST
    Human MAPK12-9248HF Recombinant Full Length Human MAPK12 Protein, GST-tagged E.coli GST
    Human MAPK12-1340H Recombinant Human MAPK12 protein, His-tagged E. coli His

    MAPK12 involved in several pathways and played different roles in them. We selected most pathways MAPK12 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway CACNA1SB; JIP1; FGF7; CACNA2D1; FGF1A; FGF20B; MAP2K3; MAP3K5; MAP3K2; MRAS
    Rap signaling pathway FLT1; NGF; FGF16; KRIT1; ACTB; KRAS; RAC1; VEGFA; ACTG1; INSR
    FoxO signaling pathway PIK3CB; PIK3R3; AKT3A; STK11; MAPK1; PRKAB1; CCNB1; CCNG2; IL6; PIK3R5
    Sphingolipid signaling pathway RELA; MAPK13; PPP2R5E; SPTLC2; PPP2R1B; MAPK8; GAB2; LASS4; S1PR2; MAPK9
    Adrenergic signaling in cardiomyocytes PLCB1; ADCY2B; TPM3; ATP1A2A; ATP2B4; PPP2R2BB; GNAI2; GNAI3; PPP2R5B; CALM1B
    VEGF signaling pathway RAF1; PTGS2B; PPP3CC; SH2D2A; AKT2; PRKCA; PPP3CCA; SHC2; PPP3CB; PTK2AA
    Osteoclast differentiation OSCAR; LILRB4; GRB2; NOX3; FCGR3B; SFPI1; LILRA4; NCF2; PIK3R3; MAPK9
    Signaling pathways regulating pluripotency of stem cells MAP2K2; SMAD3; PIK3R1; MYF5; SMAD1; WNT6; AXIN1; WNT5A; FGFR4; NRAS
    Platelet activation ARHGEF12; GUCY1B3; ITPR3; PIK3R3; ACTG1; ORAI1; PPP1CC; F2RL3; PRKACG; ACTB
    Toll-like receptor signaling pathway MAP2K4B; IFNPHI3; IFNA5; TOLLIP; MAP2K2B; PIK3CD; MAPK1; TMED7-TICAM2; CD80; RIPK1L
    NOD-like receptor signaling pathway TAB2; IKBKG; TNF; MAPK12; CCL5; NFKBIB; NFKB1; CASP8; BIRC2; NFKBIAA
    RIG-I-like receptor signaling pathway IFNA4; Ifna15; AZI2; DDX3X; IL12B; Ifna11; DHX58; IFNA3; IFNPHI1; CXCL10
    T cell receptor signaling pathway NFATC3; MUC1; CARD11; CD3E; ZAP70; MAP3K14; LCK; MAP2K2; FOS; LCP2
    Fc epsilon RI signaling pathway PIK3R1; SOS1; FCER1A; MAPK8; GAB2; LAT; PIK3CA; FCER1G; MAP2K2; MAPK11
    TNF signaling pathway MAPK12; CXCL1; SOCS3; MAPK13; MMP14; LTA; BIRC3; PIK3CB; FOS; MLKL
    Leukocyte transendothelial migration CYBB; VCL; CLDN14; CLDN8; PIK3R5; CDC42; VAV1; MAPK13; MLLT4; NOX1
    Neurotrophin signaling pathway MAPK7; SHC2; MAPKAPK2; CAMK2A; HRAS; FOXO3; MATK; NFKB1; GSK3B; PRKCD
    Retrograde endocannabinoid signaling MAPK9; GNGT1; PRKACG; GABRB3; GRIA1; GABRE; GNAQ; GRIA3; GABRQ; GNGT2
    Dopaminergic synapse PLCB3; AKT1; PLCB1; CALM3; DRD2; GNB2; GRIA1; PPP3CC; GRIA4; PRKCB
    Inflammatory mediator regulation of TRP channels NGF; PRKCG; CYP4A12A; ALOX12; CALM3; HTR2B; CALM4; PLCB4; CYP2J5; PIK3CB
    GnRH signaling pathway MAPK12; MAP3K4; CDC42L2; PLCB1; MAPK7; MAP3K1; PRKCD; CALM3; GNAS; CDC42
    Progesterone-mediated oocyte maturation PPP1R2P9; INSB; ANAPC7; INS1; RAF1A; GNAI2A; RPS6KAL; CDC16; PDE3B; INS2
    Prolactin signaling pathway GSK3B; MAP2K2; MAPK10; PIK3R3; PPIB; FOXO3; STAT5B; HRAS; SHC3; LHB
    Amyotrophic lateral sclerosis (ALS) APAF1; BAD; NEFL; TOMM40; GRIN2C; CYCS; BAX; TNFRSF1B; GRIA2; PPP3R1
    Epithelial cell signaling in Helicobacter pylori infection ATP6V0A2; CXCR2; IKBKG; ATP6V1F; RELA; ATP6V1G2; IL-8; F11R; IKBKB; ATP6V0E1
    Salmonella infection RAB7; DYNC2H1; DYNC1LI2; RAC1; MAPK14A; WASLB; CCL3L1; PKN3; MAPK1; CDC42L
    Pertussis CXCL6; CASP7; C4BPA; C4BPB; IL23; CALML3; CALM2; NOS2; IL1A; Hc
    Leishmaniasis ELK1; PTPN6; MAPK3; IRAK1; HLA-DPA1; HLA-DRB4; TGFB1; ITGB1; MAPK13; IFNGR2
    Chagas disease (American trypanosomiasis) IL1B2; TGFBR1; IRAK1; GNAQ; CFLAR; MAPK12; GNAS; C1QA; SMAD3; NFKB1
    Toxoplasmosis MAPK8; PIK3R3; HLA-DRB3; PDPK1; H2-AA; CYCS; IFNGR1; TGFB3; IFNGR2; TLR2
    Tuberculosis HSPA9; NFYB; HLA-DMA; RAB7; CYCS; TLR4; TLR1; FCGR3B; MAPK10; CALM1
    Hepatitis C OSTN; IFNA14; PPP2R2A; TP53; IFNA5; IFNA13; CLDN6; TRAF6; PDPK1; NR1H3
    Epstein-Barr virus infection HLA-DQA1; HSPA1A; IL10RA; PSMD7; NFKBIB; TRADD; GTF2B; CDK1; GSK3B; NFKB2
    Proteoglycans in cancer FLNA; WNT4; TLR2; ITGB1; FZD7; ELK1; WNT11; GPC3; MMP2; ROCK2

    MAPK12 has several biochemical functions, for example, ATP binding, MAP kinase activity, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK12 itself. We selected most functions MAPK12 had, and list some proteins which have the same functions with MAPK12. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CDC34; ERCC2; PTK2AB; SARS; NOL9; ABCD3A; DAPK3; PL10; MYO19; DGKB
    MAP kinase activity MAPK14B; MAPK14; MAPK12A; NLK2; MAPK12B; MAPK3; MAPK6; MAPK1; MAPK12; MAPK8B
    magnesium ion binding PRPS1B; ARF1; FIGNL1; HPRT1; PPM1AB; BPNT1; TESC; NT5C1B; PKLR; RPS6KA3B
    protein binding PFKM; LAMTOR2; TACR2; MAPRE2; TNFSF13B; TRIP13; PSMC3; FGR; COMT; GPN1
    protein serine/threonine kinase activity MASTL; ICK; CAMK1GA; ACVR1; NEK9; PRKCB; DAPK2; RIPK1; PHKG1A; ZNF143B

    MAPK12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK12 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK12.


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