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Official Full Name mitogen-activated protein kinase 12
Background Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
Synonyms MAPK12; mitogen-activated protein kinase 12; SAPK3; ERK6; p38gamma; PRKM12; SAPK 3; ERK-6; MAPK 12; MAP kinase 12; MAP kinase p38 gamma; stress-activated protein kinase 3; mitogen-activated protein kinase 3; extracellular signal-regulated kinase 6; mitoge
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK12-001HCL Recombinant Human MAPK12 cell lysate Insect Cell N/A
    Human MAPK12-1264H Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged Insect Cell His
    Human MAPK12-1343H Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged E.coli His
    Human MAPK12-169H Recombinant Human MAPK12 Protein, His-tagged E.coli His
    Human MAPK12-264H Recombinant Human MAPK12, Gly & Pro tagged Insect Cell His
    Human MAPK12-279H Recombinant Human MAPK12, His-GST tagged Insect Cell His
    Human MAPK12-27H Recombinant Human MAPK12 protein, GST-tagged Insect Cell GST
    Human MAPK12-30H Recombinant human biotinylated MAPK12, His-tagged E.coli His
    Human MAPK12-31377TH Recombinant Human MAPK12 N/A
    Human MAPK12-31378TH Recombinant Human MAPK12, His-tagged E.coli His
    Human MAPK12-375H Recombinant Human MAPK12, GST-tagged, Active Sf9 Insect Cell GST
    Human MAPK12-738H Recombinant Human Mitogen-activated Protein Kinase 12 E.coli N/A
    Mouse MAPK12-9528M Recombinant Mouse MAPK12 Protein Mammalian Cell His
    Rat MAPK12-3572R Recombinant Rat MAPK12 Protein Mammalian Cell His

    mapk12 involved in several pathways and played different roles in them. We selected most pathways mapk12 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with mapk12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway MAP4K2; MAP2K5; FGFR4; CACNG6A; MAP3K11; CACNG6; MAP3K5; GRB2B; TRAF6; ELK1
    Rap signaling pathway PARD6A; PLCB3; LPAR4; PRKCA; BRAF; GNAO1; FGFR1; PIK3CA; MAPK1; FGF11
    FoxO signaling pathway PRKAG3; IRS4; SGK2B; MAP2K2; PLK3; SOD2; KLF2; NRAS; KLF2A; MAPK14A
    Sphingolipid signaling pathway PLCB4; AKT1; GNA12; MAPK3; PIK3CB; SPHK1; LASS1; SGPP1; SGMS1; NRAS
    Oocyte meiosis CPEB4; ADCY1A; PGR; YWHABL; RBX1; MAPK1; ANAPC11; CCNB1; RPS6KA3; PPP2R5EA
    Adrenergic signaling in cardiomyocytes CACNA2D3; MYL2B; PRKACBB; CAMK2D; PRKACA; Adcy4; ADRB2; ATP1A2; SCN1BA; GNAS
    VEGF signaling pathway PIK3R1; AKT3A; MAP2K2B; PLCG1; MAP2K1; PLA2G4D; AKT1; VEGFA; PRKCBB; PIK3R2
    Osteoclast differentiation PIK3R1; TRAF2; FCGR2C; MAPK3; MAP2K7; TGFB2; LCK; PIK3R2; RELB; TGFBR1
    Signaling pathways regulating pluripotency of stem cells PIK3R1; STAT3; WNT8B; BMPR1A; BMP2; WNT11; ID4; NANOG; WNT7A; FZD1
    Platelet activation MYLK3; GNAS; PLA2G4C; ITPR1; FCER1G; GP5; ACTG1; SYK; TBXA2R; TLN1
    Toll-like receptor signaling pathway IFNPHI3; IFNB1; MAP2K2A; CASP8; TLR8; IL-8; MAPK12; TICAM2; IL1B; CXCL8B.3
    NOD-like receptor signaling pathway CCL2; MAP3K7IP3; PYCARD; MAPK9; TAB2; CARD8; IKBKG; CARD9; MAPK12; NAIP6
    RIG-I-like receptor signaling pathway PL10; IFNA16; CXCL8B.3; NFKBIAB; IFNB; TBKBP1; RIPK1; MAPK12A; RNF125; IL12BA
    T cell receptor signaling pathway MAP3K7; GRAP2; IKBKB; PPP3CB; NCK1; AKT1; FOS; PAK3; RHOA; CD8B1
    Fc epsilon RI signaling pathway PDPK1; IL5; MAP2K4; AKT2; RAC3; INPP5D; KRAS; RAF1; MAPK11; FCER1G
    TNF signaling pathway IKBKB; MLKL; RPS6KA4; LIF; AKT1; CXCL5; PIK3R2; VEGFC; Casp3; TNF
    Leukocyte transendothelial migration MMP9; MYL2; NOX3; CLDN18; ACTG1; CLDN6; NIPAL1; CD99; CLDN17; VASP
    Neurotrophin signaling pathway CALM1; MAPK9; BRAF; NFKBIA; MAPK13; SOS1; PSEN1; CAMK2D; SH2B2; RAF1
    Retrograde endocannabinoid signaling MAPK8; GRIA1; GABRG2; GABRD; GNG12; GNB2; DAGLB; GRIA4; GNG5; GRM5
    Dopaminergic synapse DDC; GNB1; GNG10; PPP2R2D; PRKACA; DRD5; PPP2CB; CLOCK; PRKACG; GNG3
    Inflammatory mediator regulation of TRP channels PTGER2; ASIC4; IGF1; PLA2G6; ALOX12; PPP1CA; PLA2G4F; CALM2; CAMK2D; BDKRB2
    GnRH signaling pathway MAPK12A; GNAS; PRKACA; MAPK3; MAP3K3; GNA11; PLD1; CALM1B; PLD1A; GNRH3
    Progesterone-mediated oocyte maturation PIK3R3B; MAPK13; MAPK1; MAPK12B; GNAI2B; CDC25A; INS1; PIK3R5; MAPK11; RAF1
    Prolactin signaling pathway SOCS2; SOCS7; LHB; TNFRSF11A; RELA; PIK3R5; IRF1; SLC2A2; INS2; PIK3CD
    Amyotrophic lateral sclerosis (ALS) DERL1; GRIN1; PPP3R2; PPP3CA; DAXX; NEFH; CASP12; GRIN2A; GRIA1; PPP3CB
    Epithelial cell signaling in Helicobacter pylori infection ATP6V1H; ATP6AP1; MAPK11; ADAM17; PTPN11; JAM3; ATP6V1D; CXCL1; ATP6V1G3; CXCR1
    Shigellosis MAPK13; WASL; CTTN; NFKBIB; MAPK11; MAD2L2; MAPK3; ACTG1; FBXW11; WASF1
    Salmonella infection ROCK2; MAPK8; PFN2L; TJP1; PLEKHM2; KLC1; FLNB; RHOG; RAB7; KLC2
    Pertussis MAPK11; CD14; C1QC; MAPK12; MAPK1; C4BP; MAPK13; CFL2; Il23a; Il12b; RELA
    Leishmaniasis CYBA; IL12B; HLA-DQA1; HLA-DPB1; MAPK13; TGFB3; STAT1; TNF; HLA-DRB5; HLA-DRB1
    Chagas disease (American trypanosomiasis) NFKBIA; C1QB; IRAK4; PPP2CB; C1QC; CD3G; PPP2R2B; CASP8; TNFRSF1A; PIK3R2
    Toxoplasmosis MAPK8; LAMC2; H2-AB1; IRAK1; TGFB3; LAMA4; GNAI1; HLA-DMB; LAMB2; Toxoplasma Gondii Major Surface Antigen P30
    Tuberculosis Itgam&Itgb2; IL18; TLR2; CD209B; SPHK1; CALM4; NFYB; CAP18; NFYC; FCGR2B
    Epstein-Barr virus infection TBK1; NFKBIA; POLR3GL; POLR1C; POLR3D; POLR2A; POLR1D; SNW1; PIK3R2; HLA-DRA
    Proteoglycans in cancer WNT8B; VTN; NANOG; SRC; KRAS; PPP1R12B; TRP53; CD63; HOXD10; PDPK1

    mapk12 has several biochemical functions, for example, ATP binding, MAP kinase activity, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by mapk12 itself. We selected most functions mapk12 had, and list some proteins which have the same functions with mapk12. You can find most of the proteins on our site.

    Function Related Protein
    MAP kinase activity MAPK4; MAPK3; MAPK6; NLK; MAPK8B; MAPK12A; MAPK15; MAPK14A; NLK2; MAPK7
    magnesium ion binding PRPS1; DCTPP1; PKMA; DYRK2; ENO1; RNASEH1; GSS; PIF1; MAP3K8; NIM1K
    protein binding MTERF; HIP1; EVC2; COPG; VTI1B; SEC13; PMF1; GPSM2; CNOT8; EIF4E2
    protein serine/threonine kinase activity PRKCD; STK33; PRKCA; CDC42BPA; TTBK2; PRKCZ; STRC; HIPK3; PDIK1L; CSNK1G1

    mapk12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mapk12 here. Most of them are supplied by our site. Hope this information will be useful for your research of mapk12.


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