MAPK12 Protein

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MAPK12

Official Full Name	mitogen-activated protein kinase 12
Background	Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
Synonyms	MAPK12; mitogen-activated protein kinase 12; SAPK3; ERK6; p38gamma; PRKM12; SAPK 3; ERK-6; MAPK 12; MAP kinase 12; MAP kinase p38 gamma; stress-activated protein kinase 3; mitogen-activated protein kinase 3; extracellular signal-regulated kinase 6; mitoge

Species :
Human
Mouse
Rat

Source :
E. coli
E.coli
Insect Cell
Mammalian Cell
Sf9 Insect Cell

Tag :
GST
His
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Human	MAPK12-27H	Recombinant Human MAPK12 protein, GST-tagged	Insect Cell	GST
Human	MAPK12-1264H	Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged	Insect Cell	His
Human	MAPK12-1343H	Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged	E.coli	His
Human	MAPK12-169H	Recombinant Human MAPK12 Protein, His-tagged	E.coli	His
Human	MAPK12-264H	Recombinant Human MAPK12, Gly & Pro tagged	Insect Cell	His
Human	MAPK12-279H	Recombinant Human MAPK12, His-GST tagged	Insect Cell	His
Human	MAPK12-30H	Recombinant human biotinylated MAPK12, His-tagged	E.coli	His
Human	MAPK12-31377TH	Recombinant Human MAPK12		N/A
Human	MAPK12-375H	Recombinant Human MAPK12, GST-tagged, Active	Sf9 Insect Cell	GST
Human	MAPK12-738H	Recombinant Human Mitogen-activated Protein Kinase 12	E.coli	N/A
Mouse	MAPK12-9528M	Recombinant Mouse MAPK12 Protein	Mammalian Cell	His
Rat	MAPK12-3572R	Recombinant Rat MAPK12 Protein	Mammalian Cell	His
Human	MAPK12-001HCL	Recombinant Human MAPK12 cell lysate	Insect Cell	N/A
Human	MAPK12-3014H	Recombinant Human MAPK12 protein, GST-tagged	E.coli	GST
Human	MAPK12-9248HF	Recombinant Full Length Human MAPK12 Protein, GST-tagged	E.coli	GST
Human	MAPK12-1340H	Recombinant Human MAPK12 protein, His-tagged	E. coli	His

Involved Pathway Protein Function Interacting Protein

MAPK12 involved in several pathways and played different roles in them. We selected most pathways MAPK12 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
MAPK signaling pathway	CACNA1SB; JIP1; FGF7; CACNA2D1; FGF1A; FGF20B; MAP2K3; MAP3K5; MAP3K2; MRAS
Rap signaling pathway	FLT1; NGF; FGF16; KRIT1; ACTB; KRAS; RAC1; VEGFA; ACTG1; INSR
FoxO signaling pathway	PIK3CB; PIK3R3; AKT3A; STK11; MAPK1; PRKAB1; CCNB1; CCNG2; IL6; PIK3R5
Sphingolipid signaling pathway	RELA; MAPK13; PPP2R5E; SPTLC2; PPP2R1B; MAPK8; GAB2; LASS4; S1PR2; MAPK9
Oocyte meiosis	STAG3; PPP3CB; CCNE1; INSB; PPP3R1; RPS6KA1; PPP1CAA; PPP2R5EB; PPP3CC; YWHABA
Adrenergic signaling in cardiomyocytes	PLCB1; ADCY2B; TPM3; ATP1A2A; ATP2B4; PPP2R2BB; GNAI2; GNAI3; PPP2R5B; CALM1B
VEGF signaling pathway	RAF1; PTGS2B; PPP3CC; SH2D2A; AKT2; PRKCA; PPP3CCA; SHC2; PPP3CB; PTK2AA
Osteoclast differentiation	OSCAR; LILRB4; GRB2; NOX3; FCGR3B; SFPI1; LILRA4; NCF2; PIK3R3; MAPK9
Signaling pathways regulating pluripotency of stem cells	MAP2K2; SMAD3; PIK3R1; MYF5; SMAD1; WNT6; AXIN1; WNT5A; FGFR4; NRAS
Platelet activation	ARHGEF12; GUCY1B3; ITPR3; PIK3R3; ACTG1; ORAI1; PPP1CC; F2RL3; PRKACG; ACTB
Toll-like receptor signaling pathway	MAP2K4B; IFNPHI3; IFNA5; TOLLIP; MAP2K2B; PIK3CD; MAPK1; TMED7-TICAM2; CD80; RIPK1L
NOD-like receptor signaling pathway	TAB2; IKBKG; TNF; MAPK12; CCL5; NFKBIB; NFKB1; CASP8; BIRC2; NFKBIAA
RIG-I-like receptor signaling pathway	IFNA4; Ifna15; AZI2; DDX3X; IL12B; Ifna11; DHX58; IFNA3; IFNPHI1; CXCL10
T cell receptor signaling pathway	NFATC3; MUC1; CARD11; CD3E; ZAP70; MAP3K14; LCK; MAP2K2; FOS; LCP2
Fc epsilon RI signaling pathway	PIK3R1; SOS1; FCER1A; MAPK8; GAB2; LAT; PIK3CA; FCER1G; MAP2K2; MAPK11
TNF signaling pathway	MAPK12; CXCL1; SOCS3; MAPK13; MMP14; LTA; BIRC3; PIK3CB; FOS; MLKL
Leukocyte transendothelial migration	CYBB; VCL; CLDN14; CLDN8; PIK3R5; CDC42; VAV1; MAPK13; MLLT4; NOX1
Neurotrophin signaling pathway	MAPK7; SHC2; MAPKAPK2; CAMK2A; HRAS; FOXO3; MATK; NFKB1; GSK3B; PRKCD
Retrograde endocannabinoid signaling	MAPK9; GNGT1; PRKACG; GABRB3; GRIA1; GABRE; GNAQ; GRIA3; GABRQ; GNGT2
Dopaminergic synapse	PLCB3; AKT1; PLCB1; CALM3; DRD2; GNB2; GRIA1; PPP3CC; GRIA4; PRKCB
Inflammatory mediator regulation of TRP channels	NGF; PRKCG; CYP4A12A; ALOX12; CALM3; HTR2B; CALM4; PLCB4; CYP2J5; PIK3CB
GnRH signaling pathway	MAPK12; MAP3K4; CDC42L2; PLCB1; MAPK7; MAP3K1; PRKCD; CALM3; GNAS; CDC42
Progesterone-mediated oocyte maturation	PPP1R2P9; INSB; ANAPC7; INS1; RAF1A; GNAI2A; RPS6KAL; CDC16; PDE3B; INS2
Prolactin signaling pathway	GSK3B; MAP2K2; MAPK10; PIK3R3; PPIB; FOXO3; STAT5B; HRAS; SHC3; LHB
Amyotrophic lateral sclerosis (ALS)	APAF1; BAD; NEFL; TOMM40; GRIN2C; CYCS; BAX; TNFRSF1B; GRIA2; PPP3R1
Epithelial cell signaling in Helicobacter pylori infection	ATP6V0A2; CXCR2; IKBKG; ATP6V1F; RELA; ATP6V1G2; IL-8; F11R; IKBKB; ATP6V0E1
Shigellosis	RELA; BTRC; ATG5; IKBKG; PFN4; ITGA5; MAPK11; ROCK2; WASL; RHOG
Salmonella infection	RAB7; DYNC2H1; DYNC1LI2; RAC1; MAPK14A; WASLB; CCL3L1; PKN3; MAPK1; CDC42L
Pertussis	CXCL6; CASP7; C4BPA; C4BPB; IL23; CALML3; CALM2; NOS2; IL1A; Hc
Leishmaniasis	ELK1; PTPN6; MAPK3; IRAK1; HLA-DPA1; HLA-DRB4; TGFB1; ITGB1; MAPK13; IFNGR2
Chagas disease (American trypanosomiasis)	IL1B2; TGFBR1; IRAK1; GNAQ; CFLAR; MAPK12; GNAS; C1QA; SMAD3; NFKB1
Toxoplasmosis	MAPK8; PIK3R3; HLA-DRB3; PDPK1; H2-AA; CYCS; IFNGR1; TGFB3; IFNGR2; TLR2
Tuberculosis	HSPA9; NFYB; HLA-DMA; RAB7; CYCS; TLR4; TLR1; FCGR3B; MAPK10; CALM1
Hepatitis C	OSTN; IFNA14; PPP2R2A; TP53; IFNA5; IFNA13; CLDN6; TRAF6; PDPK1; NR1H3
Influenza A	DNAJC3; IFN-a; IFNA6; TYK2; BCL2L2-PABPN1; KPNA2; IRAK4; TNFRSF1A; HLA-DMB; NXF2
Epstein-Barr virus infection	HLA-DQA1; HSPA1A; IL10RA; PSMD7; NFKBIB; TRADD; GTF2B; CDK1; GSK3B; NFKB2
Proteoglycans in cancer	FLNA; WNT4; TLR2; ITGB1; FZD7; ELK1; WNT11; GPC3; MMP2; ROCK2

MAPK12 has several biochemical functions, for example, ATP binding, MAP kinase activity, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK12 itself. We selected most functions MAPK12 had, and list some proteins which have the same functions with MAPK12. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	CDC34; ERCC2; PTK2AB; SARS; NOL9; ABCD3A; DAPK3; PL10; MYO19; DGKB
MAP kinase activity	MAPK14B; MAPK14; MAPK12A; NLK2; MAPK12B; MAPK3; MAPK6; MAPK1; MAPK12; MAPK8B
magnesium ion binding	PRPS1B; ARF1; FIGNL1; HPRT1; PPM1AB; BPNT1; TESC; NT5C1B; PKLR; RPS6KA3B
protein binding	PFKM; LAMTOR2; TACR2; MAPRE2; TNFSF13B; TRIP13; PSMC3; FGR; COMT; GPN1
protein serine/threonine kinase activity	MASTL; ICK; CAMK1GA; ACVR1; NEK9; PRKCB; DAPK2; RIPK1; PHKG1A; ZNF143B

MAPK12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK12 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK12.

SIAH1; saicar; PKM; PTPN4; SRPK1; DUSP1; DLG1; PKN1; TERF1; GTF2I; PDGFRL; MAPK1; PRPF4B; MAPK15

MAPK12

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MAPK12

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