MAPK3 Protein

MAPK3

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MAPK3

Official Full Name MAPK3 mitogen-activated protein kinase 3
Synonyms MAPK3; mitogen-activated protein kinase 3; PRKM3; ERK1; p44erk1; p44mapk; MAPK 1; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; insulin-stimulated MAP2 kinase; mitogen-activated protein kinase 1; extracellular signal-related kinase 1; extracellular signal-regulated kinase 1; microtubule-associated protein 2 kinase; ERT2; ERK-1; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MGC20180;
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • His&GST
    • MBP
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK3-1031M Recombinant Human MAPK3 protein E.coli N/A
    Human MAPK3-1048H Recombinant Human Mitogen-Activated Protein Kinase 3 (Active), GST-Tagged E.coli GST
    Human MAPK3-1049H Recombinant Human Mitogen-Activated Protein Kinase 3 (Unactive), GST-Tagged E.coli GST
    Human MAPK3-1517H Recombinant Human MAPK3 protein E.coli N/A
    Human MAPK3-2787H Recombinant Human MAPK3, His-tagged E.coli His
    Human MAPK3-28694TH Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-28699TH Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-286H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-287H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-288H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-28H Recombinant human biotinylated ERK1, His-tagged E.coli His
    Human MAPK3-307H Recombinant Human MAPK3 Protein E.coli
    Human MAPK3-34H Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-36H Recombinant Human MAPK3 E.coli N/A
    Mouse MAPK3-9534M Recombinant Mouse MAPK3 Protein Mammalian Cell His
    Rat MAPK3-3574R Recombinant Rat MAPK3 Protein Mammalian Cell His
    Zebrafish MAPK3-11551Z Recombinant Zebrafish MAPK3 Mammalian Cell His
    Human MAPK3-4494HCL Recombinant Human MAPK3 293 Cell Lysate HEK293 N/A
    Human MAPK3-2068HF Recombinant Full Length Human MAPK3 Protein, GST-tagged E.coli GST
    Human ERK1-125H Recombinant Human MAPK3 protein, His-tagged E.coli His
    Human MAPK3-061H Recombinant Human MAPK3 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human MAPK3-1050H Recombinant Human MAPK3 Protein, His/GST-Tagged E. coli His&GST
    Mouse Mapk3-3942M Recombinant Mouse Mapk3 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    MAPK3 involved in several pathways and played different roles in them. We selected most pathways MAPK3 participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway RRAS2; PPP3CC; ELK4; AKT1; FGF14; MAP2K4B; FGF2; GADD45BA; MAP4K3; FGF1
    ErbB signaling pathway MAPK8B; CBLB; BRAF; MAP2K4B; CBL; PAK6B; MAPK10; SHC3; CBLC; MAP2K2B
    Ras signaling pathway AKT1; BAD; PIK3CA; FGF11; FGF14; FGF13; MAPK1; GRB2; PAK7; CALM3
    Rap signaling pathway PLCB2; FGF12; MAP2K6; PLCB4; SRC; MAPK1; KLK1B4; MAP2K3; VEGFA; VEGFB
    cGMP-PKG signaling pathway AGTR1A; PRKG1; ATP1A2; CALM1; CALM2; MYLK4; ATP1A3; PDE2A; PPIF; AGTR1B
    cAMP signaling pathway CNGA3; ROCK1; BAD; CALM3; PLD1; CNGA2; NFATC1; FOS; ARAP3; MC2R
    Chemokine signaling pathway XCR1; RAP1A; CCL25; PREX1; CCL11; AMCF-II; CCL3L3; CCL16; PLCB3; CCR7
    HIF- signaling pathway IL6; MTOR; TFRC; EIF4E2; PIK3R5; ENO3; ARNT; EGLN1; HIF1A; PIK3R1
    FoxO signaling pathway RBL2; ARAF; PRKAB1; MAPK14A; SGK2; SGK3; INS1; PRMT1; IGF1RA; PIK3R1
    Sphingolipid signaling pathway TP53; RELA; PPP2R1A; MAPK3; PPP2R5A; PRKCB; MS4A2; ACER1; LASS1; GNA12
    Phospholipase D signaling pathway CYTH3; LPAR2; GRM7; AVP; SYK; PLD2; AGTR1B; LPAR3; RAF1; AGTR1A
    Oocyte meiosis FBXO5; CAMK2G; PPP1CA; YWHAZ; ANAPC2; CAMK2D2; CALM2B; CPEB2; ANAPC4; INS1
    mTOR signaling pathway AKT1S1; DEPDC6; VEGFAB; RRAGD; ULK1; RPS6KAL; PRR5; PIK3CD; RRAGCB; VEGFAA
    PIK-Akt signaling pathway HRAS; GRB2; GH2; IFNA4; FN1; ITGB7; IKBKB; Gh; VTN; COL4A1
    Adrenergic signaling in cardiomyocytes SCN5A; CACNA1SB; PRKACAA; PIK3CD; PPP2R1A; CALM2B; PPP2R2D; CACNA1C; RYR2; ATP2A2
    Vascular smooth muscle contraction PLA2G4A; PRKCHA; BRAF; ACTG2; ROCK2A; CACNA1D; AVPR1B; PLCB1; CALM3B; ADCY1A
    Dorso-ventral axis formation NOTCH1; PPP1R2P9; CPEB1A; CPEB4; ETV7; SPIRE1; NOTCH3; MAPK3; SOS1; MAPK1
    TGF-beta signaling pathway BMP7; NOG; RHOA; SKP1; TGFB1; ID2B; THBS1; IFNG1-2; NOG3; MAPK3
    Axon guidance SPRED1; COL9A1; EFNA1A; SCN4A; RAC2; GFRA4; ITGB1B.1; EPHA4; LIMK2; SEMA3AA
    VEGF signaling pathway PIK3CA; PIK3CG; PPP3CCA; PTK2AB; RAC3B; PPP3CC; MAPKAPK2; HRAS; MAP2K2; VEGFAB
    Osteoclast differentiation LILRA4; AKT2; CYBA; IFNB1; CYLD; NOX3; BLNK; ACP5; PIK3R1; SFPI1
    Focal adhesion PTK2AA; COL24A1; LAMA3; DOCK1; ITGAV; LAMA5; VAV3; MYL9A; PPP1CA; RHOA
    Adherens junction FER; RAC1A; CTNNA1; CTNNA2; INSRA; RHOAA; WASB; ACTN1; LMO7; PTPRFB
    Gap junction MAPK7; PDGFC; TUBB6; GRM1; PRKACB; RAF1; RAF1A; TUBA3E; PRKACAB; GRB2A
    Signaling pathways regulating pluripotency of stem cells SMAD9; DLX5; WNT7B; MAP2K1; MEIS1; ONECUT1; BMP2; ID3; WNT6; LEFTY2
    Platelet activation RHOA; PPP1CA; PIK3CA; MAPK11; VWF; COL27A1; F2RL3; GNAS; GP6; PRKCI
    Toll-like receptor signaling pathway MAP2K7; MAPK12A; IL12A; NFKBIAB; MAPK14A; CXCL9; TLR4BA; TLR7; TLR2; TMED7-TICAM2
    NOD-like receptor signaling pathway TNF; IL8L1; NLRP1; CARD18; CASPA; MAPK10; TRAF6; CXCL2; NFKBIAB; IL1B
    Natural killer cell mediated cytotoxicity FCGR3; RAC3; FYN; LAT; SHC2; KIR2DL1; SH2D1A; PTPN6; PTK2B; VAV2
    T cell receptor signaling pathway BCL10; PDCD1; NFATC2; TNF; CD28; CBLB; AKT1; NFKBIE; DBNLB; PAK7
    B cell receptor signaling pathway ARPC3; BANK1; RAF1; CMTM3; PIK3R1; GSK3B; DOK1; CD19; PTPN18; PIK3R3
    Fc epsilon RI signaling pathway RAC3; PLCG1; PLA2G4B; LAT; RAC1; VAV2; MAPK1; PIK3R3; MAP2K6; IL13
    Fc gamma R-mediated phagocytosis AKT1; ASAP3; PIP5K1A; RPS6KB2; PIK3R2; PIP5K1B; PIK3CD; FCGR3A; MARCKS; GSN
    TNF signaling pathway CX3CL1; MAP3K7IP3; MAPK12; CCL2; MAPK3; ICAM1; MMP9; CREB3L1; ITCH; MAP3K5
    Circadian entrainment PLCB2; GNG5; CAMK2B; PRKCA; Adcy4; AKR1C1; CALM3; GRIN1; PRKACG; GNGT2
    Long-term potentiation ATF4; RAP1A; GRIN2C; MAP2K1; MAPK3; RPS6KA3; PRKCA; PLCB4; CAMK2D; ARAF
    Neurotrophin signaling pathway SH2B3; RAP1A; SH2B1; MAPK13; KIDINS220; IKBKB; MAPK1; RPS6KA2; MAP3K1; NTRK2
    Retrograde endocannabinoid signaling MAPK1; GNG4; SLC17A7; GABRR2; SLC17A8; GNG2; GABRB1; GABRG2; Adcy4; DAGLB
    Glutamatergic synapse SLC38A2; GRIK4; GRM2; PPP3CC; GRIA2; HOMER3; GRIN2A; PPP3CA; GLS; PLA2G4C
    Cholinergic synapse CREB5; SLC5A7; GNB1; CREB3L3; GNG13; CHRNA3; CAMK2A; GNG7; PRKACB; CAMK2D
    Serotonergic synapse GNG5; GNG11; TPH1; HTR1A; PLCB3; HTR3A; CYP2D10; GNB2; GNG13; RAF1
    Long-term depression PLA2G4F; BRAF; PRKCG; GRID2; CRHR1; GNAI3; GRIA3; CRH; RAF1; GUCY1A3
    Regulation of actin cytoskeleton Fgf15; FGF1; ITGA2; LIMK1A; FGF20B; PFN2; VAV2; ITGB6; ACTN2B; CHRM5A
    Insulin signaling pathway FOXO1A; CALML5; PRKAR2AA; CBL; PPP1R3A; PRKAR1A; PYGM; FLOT2A; PTPRF; PCK1
    GnRH signaling pathway CALM3B; MAPK8B; CDC42L2; MAPK12A; PRKACG; MAP2K3; GNA11B; PLD2; KRAS; HRASA
    Progesterone-mediated oocyte maturation CPEB3; INS2; ANAPC7; CDC16; ANAPC4; MAPK8B; FZR1A; HSP90AA1; AKT1; CDC23
    Estrogen signaling pathway OPRM1; SP1; MAP2K2; HSP90AA1; SRC; HSPA8; SHC3; HSPA1L; GNAI3; CREB3L3
    Melanogenesis FZD1; EP300; PRKACB; MITF; MAP2K2A; MITFA; Kitl; GNAI2; WNT3A; ASIP
    Prolactin signaling pathway GRB2; KRAS; GALT; MAP2K2; SIRPA; PIK3CG; STAT5A; SOCS1; RELA; SOS1
    Thyroid hormone signaling pathway PLCB1; GATA4; PIK3CB; HDAC3; MAP2K1; PIK3CA; GSK3B; PRKACG; PRKCG; PLCD1
    Oxytocin signaling pathway RYR2; GNAI3; NRAS; CACNB2; MEF2C; PRKAB1; CCND1; PPP3R2; PRKCG; MAP2K2
    Type II diabetes mellitus INS2; ADIPOQ; HKDC1; HK3; INS-IGF2; PRKCD; INS1; MTOR; PKLR; PIK3CG
    Aldosterone-regulated sodium reabsorption SLC9A3R2; HSD11B2; SFN; ATP1B2; PIK3R2; SCNN1B; INS1; ATP1B3; SGK1; MAPK3
    Alzheimers disease PPP3CA; NDUFB11; SDHA; IL1B; NDUFV1; UQCR11; NDUFB10; CASP12; APH1C; EIF2AK3
    Prion diseases NOTCH1; C1QC; MAP2K1; C5; FYN; C8B; STIP1; PRKACG; C9; C1QB
    Alcoholism HIST1H2AG; GNG5; ATF2; GNGT2; HIST1H2AE; HIST1H2BE; HIST1H3A; HIST1H3I; HIST1H3G; HIST2H2AA2
    Shigellosis NFKBIA; RELA; WASF1; DIAPH1; MAPK11; ATG5; NFKB1; SRC; VCL; PFN3
    Salmonella infection PYCARD; WASF1; KLC4; CCL3; RAC1; WASB; DYNC1LI2; ROCK2; NOS2; NLRC4
    Pertussis ITGB2L; IRF3; C1R; CD14; RHOA; CXCL6; MAPK11; C5; CALML5; IL12A
    Leishmaniasis HLA-DPA1; IFNGR1; TLR4; IRAK1; MAPK13; H2-AB1; FCGR3; TGFB1; RELA; TGFB3
    Chagas disease (American trypanosomiasis) TGFB1; CCL3L1; FOS; TICAM1; PPP2CB; MAPK3; AKT2; C1QA; LOC100033925; CCL5
    Toxoplasmosis NFKB1; IFNGR1; MAP3K7; LAMB4; NFKBIA; Toxoplasma Gondii Dense Granule Protein 7; LDLR; MAPK10; PPIF; CASP9
    Tuberculosis IRAK4; CLEC4M; PIK3C3; IFNA10; NOS2; ITGAM; BID; CLEC4E; IL18; CLEC7A
    Hepatitis C IFNA4; CLDN10; IFNA6; EIF2AK4; CLDN4; IRF3; CLDN23; PPP2R2B; NR1H3; PPP2CB
    Hepatitis B TGFB1; CASP10; IL6; HRAS; PIK3R5; EGR2; STAT5A; IFNA10; TNF; IKBKG
    Influenza A RNASEL; IFNA14; HSPA6; MAPK12; IFNA10; IL18; TNFRSF10D; HSPA1A; MYD88; FAS
    Pathways in cancer Casp3; GNG8; KITLG; FN1; PDGFB; FGFR1; ITGAV; RAC2; PIK3R2; LEF1
    Viral carcinogenesis HLA-G; CASP8; HIST1H4K; SRC; HIST1H2BN; YWHAZ; DNAJA3; TP53; HIST1H2BA; HDAC3
    Proteoglycans in cancer SOS1; WNT11; CCND1; SDC1; ITGA5; CBL; HSPB2; MAPK12; GPC1; MDM2
    Colorectal cancer MSH3; SMAD4; PIK3CB; ARAF; RALGDS; PIK3CA; MAPK1; Casp3; MAP2K1; FOS
    Renal cell carcinoma NRAS; RAC1; PAK2; PIK3R2; PIK3CD; MAP2K1; SOS1; FH; TGFA; PIK3R3
    Pancreatic cancer RALGDS; PIK3R1; MAPK10; PLD1; BCL2L1; AKT2; RALBP1; PIK3R2; RAD51; MAPK1
    Endometrial cancer PIK3R1; HRAS; MAP2K1; NRAS; PTEN; LEF1; ILK; TP53; TCF7L2; TCF7
    Glioma SHC4; CAMK2D; PIK3CA; IGF1R; KRAS; AKT2; PIK3CB; CAMK2B; PIK3R5; CALML3
    Prostate cancer IGF1R; CCND1; CPN1; NDRG1; AKT2; CREB3L1; FGFR1; CCNE1; GRB2; PIK3CG
    Thyroid cancer TCF7; CDH1; KRAS; BRAF; RXRB; MAP2K1; TPR; RXRG; PAX8; LEF1
    Melanoma FGF22; ARAF; PDGFC; HRAS; PTEN; PIK3CG; FGF13; PDGFRB; RB1; MITF
    Bladder cancer RB1; RPS6KA5; MAPK1; MMP1A; ERBB2; EGF; MMP9; RAF1; TRP53; CDK4
    Chronic myeloid leukemia ARAF; MECOM; PIK3CD; PIK3CB; NFKBIA; KRAS; IKBKB; SHC4; RELA; NRAS
    Acute myeloid leukemia MAP2K2; CCND1; IKBKB; KIT; BAD; PIK3CG; SFPI1; SPI1; MAP2K1; MAPK1
    Non-small cell lung cancer HRAS; MAPK1; MAP2K2; TRP53; ARAF; PIK3R5; TGFA; RXRB; PIK3R3; PIK3R1
    Central carbon metabolism in cancer IDH1; FGFR3; LDHA; KIT; HK1; PFKL; TRP53; C12orf5; GLS; PIK3CD
    Choline metabolism in cancer EGF; SLC5A7; PPAP2A; PIK3CA; PPAP2B; PDGFB; PRKCB; PLA2G4B; DGKA; EIF4EBP1

    MAPK3 has several biochemical functions, for example, ATP binding, MAP kinase activity, phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK3 itself. We selected most functions MAPK3 had, and list some proteins which have the same functions with MAPK3. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ILK; PRKCA; PIP4K2A; CTPS2; CCT4; SYN3; MYLK3; SMCHD1; ABCG2C; ACTB
    MAP kinase activity MAPK7; MAPK6; MAPK15; MAPK12A; MAPK12; NLK; MAPK8A; MAPK14A; NLK1; MAPK3
    phosphatase binding PPARA; TPRN; PPP1R26; DLG1; SLC9A3R2; SH2D4A; KIAA0649; PPP1R21; PPP1R35; MAPK3
    phosphotyrosine binding CBLC; LDLRAP1; CBL; SAMSN1; CBLB; PTPN3; ZAP70; MAPK1; MAPK3; GRB2
    protein binding TAB1; TMEM100; WASH1; EPM2A; NF2; LGALS2; ZBTB43; AMOTL2A; PLEKHG4; PCSK9
    scaffold protein binding SCN5A; DSP; SRC; SHANK1; NLGN4Y; HOMER1; PARK7; MAPK3; NLGN3; CRIPT

    MAPK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK3.

    DUSP1; PTPRJ; MAPK14; DHPS; Ptprr

    Blaha, M; Nemcova, L; et al. Cyclic guanosine monophosphate does not inhibit gonadotropin-induced activation of mitogen-activated protein kinase 3/1 in pig cumulus-oocyte complexes. REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY 13:-(2015).
    Chen, TC; Lin, KT; et al. Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein-Protein Interactions in a Pathway Network. JOURNAL OF PROTEOME RESEARCH 13:5339-5346(2014).

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