mapk3

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mapk3

Official Full Name MAPK3 mitogen-activated protein kinase 3
Synonyms MAPK3; mitogen-activated protein kinase 3; PRKM3; ERK1; p44erk1; p44mapk; MAPK 1; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; insulin-stimulated MAP2 kinase; mitogen-activated protein kinase 1; extracellular signal-related kinase 1; extracellular signal-regulated kinase 1; microtubule-associated protein 2 kinase; ERT2; ERK-1; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MGC20180;
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • His&GST
    • MBP
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK3-1050H Recombinant Human MAPK3 Protein, His/GST-Tagged E. coli His&GST
    Human ERK1-125H Recombinant Human MAPK3 protein, His-tagged E.coli His
    Human MAPK3-1031M Recombinant Human MAPK3 protein E.coli N/A
    Human MAPK3-1048H Recombinant Human Mitogen-Activated Protein Kinase 3 (Active), GST-Tagged E.coli GST
    Human MAPK3-1049H Recombinant Human Mitogen-Activated Protein Kinase 3 (Unactive), GST-Tagged E.coli GST
    Human MAPK3-1517H Recombinant Human MAPK3 protein E.coli N/A
    Human MAPK3-2787H Recombinant Human MAPK3, His-tagged E.coli His
    Human MAPK3-28694TH Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-28699TH Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-286H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-287H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-288H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-28H Recombinant human biotinylated ERK1, His-tagged E.coli His
    Human MAPK3-307H Recombinant Human Mitogen-activated Protein Kinase 3, Active Sf9 Insect Cell N/A
    Human MAPK3-34H Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-36H Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-4494HCL Recombinant Human MAPK3 293 Cell Lysate HEK293 N/A
    Mouse MAPK3-9534M Recombinant Mouse MAPK3 Protein Mammalian Cell His
    Rat MAPK3-3574R Recombinant Rat MAPK3 Protein Mammalian Cell His
    Zebrafish MAPK3-11551Z Recombinant Zebrafish MAPK3 Mammalian Cell His

    mapk3 involved in several pathways and played different roles in them. We selected most pathways mapk3 participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with mapk3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway CACNG8; RPS6KA3; AKT2; TNF; GNA12; PPM1A; MAP3K2; MAPK11; ACVR1C; HSC70
    ErbB signaling pathway PTK2AB; PIK3R1; GSK3B; MAP2K2B; CAMK2D; PIK3R5; NCK2B; ABL1; ELK1; AKT1
    Ras signaling pathway RAB5C; CDC42; RAC2; FGF21; TEK; PGF; KRAS; PAK3; NF1; GNG8
    Rap signaling pathway VEGFB; GRIN2B; PIK3R2; FLT1; FIGF; MLLT4; ITGAM; ITGB2L; ARAP3; MRAS
    cGMP-PKG signaling pathway ROCK2; PDE3B; ATP2B4; CREB5; PPP3CA; MEF2C; IRS2; BNP; PIK3R5; PIK3CD
    cAMP signaling pathway FSHB; CALM4; HTR1F; PPP1CC; SOX9; RAC1; HTR6; GLP1R; HCN4; FOS
    Chemokine signaling pathway NRAS; CCL16; CCL21B; SHC4; AKT1; CCL5; CXCL5; HRAS; CCL1; GNG5
    HIF- signaling pathway INSR; ARNT; NOS3; ANGPT1; IL6R; HIF1A; HMOX1; NOS2; VEGFA; PRKCA
    FoxO signaling pathway TGFBR1; SGK2B; NLK2; TGFB2; G6PC3; CCNB2; HRAS; TGFB1; TNFSF10; PRMT1
    Sphingolipid signaling pathway GNA12; RAC2; PPP2R5D; MAPK1; PIK3R5; TNF; PLCB2; PPP2R3C; FCER1G; MAPK9
    Phospholipase D signaling pathway MTOR; PIK3CB; INS1; F2R; AGTR1B; PTGFR; PPAP2C; PLA2G4C; PLCG2; AGPAT5
    Oocyte meiosis CDC23; PRKACAB; PPP3CC; ITPR3; IGF1R; REC8; YWHAQA; ANAPC1; YWHAE1; CAMK2G1
    mTOR signaling pathway PIK3CD; PRKCBA; PTENB; INS2; STK11; PRR5; PIK3R3; PIK3R3B; EIF4EA; MAPK1
    PIK-Akt signaling pathway IFNA14; PDGFC; TP53; GSK3B; CASP9; PPP2R5C; TNR; THBS2; OSM; EIF4E2
    Adrenergic signaling in cardiomyocytes CACNG1; ACTC1; PIK3R1; PPP2R5B; PPP2R1B; CACNB3; CALM1; CALM1A; BCL2; CREB5
    Vascular smooth muscle contraction PRKACG; GNAQ; CALM1A; MYLK4; RHOAB; RAF1A; ADORA2AA; ROCK2A; CALML5; PLA2G10
    Dorso-ventral axis formation CPEB1; MAPK3; ETS2; MAP2K1; SPIRE1; SPIRE1A; EGFRA; GRB2; CPEB2; CPEB1A
    TGF-beta signaling pathway BMPR1AA; TFDP1; SPAW; NOG3; AMH; BMPR1B; ID2; BMP7B; SKP1; TGFB3
    Axon guidance NCAN; HRAS; EFNB3; CSF2; LRRC4C; EPHA5; AP2B1; SCN9A; GFRA1; MET
    VEGF signaling pathway PIK3R2; PTK2AA; RAC3A; PPP3CA; CASP9; PPP3CC; PTGS2A; PLA2G4C; PRKCBB; PLA2G4AA
    Osteoclast differentiation CSF1; FCGR3A; PPP3R1; FHL2; TNFRSF1A; FCGR2A; FCGR1A; RELB; NFATC1; ACP5
    Focal adhesion PTK2AB; PIP5K1C; PARVB; ITGAV; RAP1B; COL27A1; COL2A1B; PIK3R3A; PXNA; SHC4
    Adherens junction CSNK2A2; TGFBR1; AASS; PTPRF; ACTN1; PVRL1B; PARD3; INSRB; WAS; TCF7L1A
    Gap junction PDGFB; MAPK3; CX35B; PRKACBB; GJA1; CDK1; DRD1B; GNA11; RAF1; HRASA
    Signaling pathways regulating pluripotency of stem cells PIK3R5; ZIC3; LEFTY2; KRAS; ID4; ACVR1; WNT9A; SMAD1; PIK3CD; FGF2
    Platelet activation MYLK2; PRKG2; ITGA2; TLN1; MAPK3; PLA2G4F; ITGA2B; RHOA; AKT1; LCP2
    Toll-like receptor signaling pathway IKBKG; AKT3A; IKBKE; TLR1; IRF3; PIK3CD; TLR7; PIK3CB; PIK3R3; TLR1LA
    NOD-like receptor signaling pathway MAPK13; IL8L1; HSP90AA1; MAPK3; MAPK11; MAPK12; MAP3K7; MAPK9; BIRC3; TRAF6
    Natural killer cell mediated cytotoxicity CD247; PRKCG; IFNA7; NFATC2; HLA-C; PTK2B; RAET1E; HLA-G; FCGR3A; KLRC4-KLRK1
    T cell receptor signaling pathway PDCD1; GRB2; PIK3CG; DBNLB; MAP3K7; LCP2; FYN; PIK3CB; CD247; PPP3CB
    B cell receptor signaling pathway PLCG2; PIK3CA; CDK7; Cd79a, Cd79b; GSK3B; PPP3CB; CRK; STAP1; NFKBIA; DUSP6
    Fc epsilon RI signaling pathway MAP2K2; FCER1G; VAV3; VAV2; PIK3R2; MAP2K3; LCP2; RAC1; MAPK9; GRB2
    Fc gamma R-mediated phagocytosis INPP5D; PIP5K1C; PPAP2A; ARPC5L; LIMK2; PIK3R3; PRKCG; MARCKSL1; PIK3R5; PRKCD
    TNF signaling pathway CASP8; PIK3CB; MAP3K5; PIK3R3; CXCL1; IKBKB; MAP2K1; PIK3R5; MMP3; AKT1
    Circadian entrainment RYR3; GRIA1; GRIA3; GNG3; PLCB3; GNB1; GNG7; CAMK2A; GNAO1; CALM1
    Long-term potentiation PPP1R1A; ITPR3; PPP1CB; PLCB4; RAP1B; CALM2; MAPK1; MAP2K2; GNAQ; PRKCA
    Neurotrophin signaling pathway MAPK9; HRAS; PIK3CB; CAMK2A; TP53; MATK; PSEN1; AKT1; YWHAE; PRKCD
    Retrograde endocannabinoid signaling GRM5; GABRB3; GABRA1; DAGLB; GNB4; GNG10; GABRB1; MAPK9; PLCB3; GABRG2
    Glutamatergic synapse GLS2; SLC38A3; GRM2; GNAQ; SLC17A7; PPP3R1; PPP3R2; MAPK3; GRIA1; SHANK2
    Cholinergic synapse AKR1C1; CHRM2; PIK3CB; GNG11; CHRNB2; BCL2; PRKCB; CHAT; KCNJ2; PRKCA
    Serotonergic synapse GNGT2; HTR2A; GNG11; GNG13; PRKCB; ALOX15B; SLC18A2; GNG10; HTR4; PLCB4
    Long-term depression GRID2; GRIA1; CRHR1; MAPK3; PRKCG; NOS1; GNAI3; GUCY1A3; PLA2G4D; BRAF
    Regulation of actin cytoskeleton DIAP1; GSN; FGD; FGF1B; RAC1A; SLC9A1; ARPC5LA; PIK3R3A; ITGA7; PDGFRA
    Insulin signaling pathway GSK3B; PPP1R3C; RPS6KB1B; CALM2; SOCS2; SLC2A4; PIK3R3; HKDC1; SHC1; FLOT2B
    GnRH signaling pathway GNRHR1; PRKCB; CAMK2G1; CAMK2D2; GNA15.4; EGFRA; MAPK12; CACNA1D; ATF4B1; MAP3K1
    Progesterone-mediated oocyte maturation PRKACBB; MAPK14A; HSP90AA1.1; CPEB2; MAPK14B; CDC27; ANAPC1; MAPK13; RPS6KA3B; CPEB4
    Estrogen signaling pathway ITPR3; CREB3L2; HSPA1B; HSP90AA1; SHC2; PRKACB; GABBR1; MMP2; ITPR1; MAP2K2
    Melanogenesis CAMK2G1; TYR; WNT9B; CALM2B; CALM4; DCT; GNAI2; FZD9B; RAF1B; WNT3
    Prolactin signaling pathway ESR1; PRL; NFKB1; LHCGR; PIK3CB; MAPK8; MAPK13; HRAS; CCND2; SOS1
    Thyroid hormone signaling pathway FXYD2; ATP1A3; PRKACB; ACTB; RHEB; MAP2K1; RXRB; PRKCB; HDAC3; GATA4
    Oxytocin signaling pathway SRC; CACNB3; NFATC3; MAP2K1; MYLK; MEF2C; PRKAA2; GUCY1B3; CAMK1; PPP1R12B
    Type II diabetes mellitus MAPK1; PKM2; MAPK10; MAPK8; MAPK3; PRKCZ; PIK3R2; IRS4; CACNA1G; PRKCD
    Aldosterone-regulated sodium reabsorption SGK1; SCNN1G; SFN; KRAS; PRKCA; PRKCB; PRKCG; SLC9A3R2; FXYD4; MAPK3
    Alzheimers disease CDK5R1; NDUFS7; COX6B2; CAPN2; CALM1; NDUFA2; NDUFA1; ATP5G3; GRIN1; NDUFB9
    Prion diseases IL1A; LOC100033925; BAX; HSPA5; CCL5; NOTCH1; IL6; Hc; C5; CASP12
    Alcoholism DRD1; HIST1H2BF; MAPK1; HIST1H3A; HIST1H4I; CAMK4; H2BFWT; SLC29A1; SLC18A2; GNG8
    Shigellosis ROCK2; DIAPH1; PFN3; MAPK12; IL-8; MAPK1; IKBKB; WASL; RAC1; U2AF1L4
    Salmonella infection RHOGC; MAPK11; ROCK2A; CDC42L2; PYCARD; IL8L2; CDC42L; CXCL8B.3; KLC1A; TLR5
    Pertussis ITGB1; LY96; ITGA5; CALML3; AMCF-II; C1S; C2; SERPING1; GNAI2; Il23a
    Leishmaniasis CYBA; H2-AA; HLA-DMA; HLA-DMB; IL1B; TGFB2; TNF; HLA-DRB5; FCGR1A; MAP3K7
    Chagas disease (American trypanosomiasis) PIK3CG; PIK3R3; CD3G; GNAI2; MYD88; SMAD3; IFNGR1; CCL2; GNAI3; MAPK9
    Toxoplasmosis IL12A; ITGA6; Toxoplasma Gondii Dense Granule Protein 7; HSPA1L; HLA-DQA2; PIK3CD; HLA-DRB3; TAB2; STAT1; SOCS1
    Tuberculosis CAP18; IRAK1; IFNG; FCGR3; IFNA16; PPP3CB; TRAF6; CASP9; IFNA6; BAD
    Hepatitis C CLDN6; IRF1; NFKB1; DDX58; GRB2; IFIT1; TRADD; CD81; NFKBIA; CLDN20
    Hepatitis B IFNA6; EGR3; MAVS; TRP53; CREB5; IFNA21; IKBKB; CREB3L1; IFNAR1; MYD88
    Influenza A PIK3R5; IFNA8; VDAC1; PRSS2; IRAK4; EP300; RELA; STAT2; PABPN1L; PRKCA
    Pathways in cancer PGF; CXCR4; TGFBR2; FGF19; RAC2; BRCA2; PLCB1; IGF1R; HIF1A; PRKCA
    Viral carcinogenesis HIST1H2BG; H2-Q10; RBPJ; ACTN4; BAK1; HLA-B; STAT5A; NRAS; HIST1H4F; HIST1H2BP
    Proteoglycans in cancer EZR; PLAU; PLCG1; ANK1; ITGAV; ROCK2; MMP2; PTCH1; SLC9A1; WNT1
    Colorectal cancer PIK3CG; SMAD2; Casp3; BRAF; MAPK3; RAF1; TP53; BIRC5; PIK3R1; CCND1
    Renal cell carcinoma PAK2; TGFA; SOS1; PIK3CB; PDGFB; KRAS; AKT2; MET; HIF1A; PAK1
    Pancreatic cancer TGFBR1; MAPK10; RAC1; ARAF; RALB; STAT3; NFKB1; AKT2; TGFBR2; MAPK9
    Endometrial cancer PIK3CA; CTNNA2; AXIN1; PIK3R3; PDPK1; RAF1; PTEN; CCND1; TCF7; TCF7L2
    Glioma PIK3R1; NRAS; PDGFB; AKT2; TRP53; CAMK2B; PTEN; PLCG1; CALML3; ARAF
    Prostate cancer PDGFRB; KRAS; NDRG1; FGFR2; MAPK3; SMARCD1; RB1; CCND1; GRB2; NFKB1
    Thyroid cancer MAPK3; MAP2K1; NCOA4; TPR; RXRB; TCF7L2; MAP2K2; MAPK1; NTRK1; CCND1
    Melanoma TP53; FGF6; FGF11; HRAS; PIK3CA; RAF1; FGF5; ARAF; PDGFC; FGF12
    Bladder cancer CDKN2A; IL-8; E2F2; RPS6KA5; ARAF; MMP9; E2F3; TRP53; MAP2K1; MAP2K2
    Chronic myeloid leukemia SHC2; TGFB3; NRAS; CBLB; PTPN11; MDM2; NFKB1; MAPK1; TGFBR1; AKT1
    Acute myeloid leukemia TCF7L2; STAT5B; TCF7; RPS6KB2; PIM2; SFPI1; CCND1; SPI1; FLT3; PIK3R2
    Non-small cell lung cancer TRP53; NRAS; MAPK3; PIK3R3; KRAS; PRKCB; BRAF; PIK3CB; RB1; RXRG
    Central carbon metabolism in cancer PFKL; RET; PDGFRB; HK3; GLS; GLS2; MTOR; FLT3; C12orf5; SLC16A3
    Choline metabolism in cancer PLA2G4D; Pdgfa&Pdgfb; WASF3; SLC44A1; EGF; PDGFA; PRKCA; WASF2; CHKA; SLC22A2

    mapk3 has several biochemical functions, for example, ATP binding, MAP kinase activity, phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by mapk3 itself. We selected most functions mapk3 had, and list some proteins which have the same functions with mapk3. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding WARS; RUNX2; KIF3C; KIF12; PFKMB; CDK5; NEK10; SGK3; PET112L; ABCE1
    MAP kinase activity MAPK1; MAPK8B; MAPK11; MAPK15; MAPK12; MAPK13; MAPK14; MAPK14A; MAPK6; NLK1
    phosphatase binding TSC2; SLC9A3R2; MAGI2; CSRNP2; SH3YL1; MAST2; MAPK3; PPP1R26; SLC9A3R1; PPP1R27
    phosphotyrosine binding PTPN3; MAPK1; CBL; CBLC; CBLB; GRB2; FGR; MAPK3; LDLRAP1; SAMSN1
    protein binding PCK2; ITGA6; NFE2; TSPAN6; PBX1; INSIG1; TBC1D20; FEM1C; LHX9; SEC22B
    scaffold protein binding NOS3; NCK2; ADCY6; SCN5A; MAPK3; KRT5; TREM2; NLGN4Y; ATP2B4; SHANK3

    mapk3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mapk3 here. Most of them are supplied by our site. Hope this information will be useful for your research of mapk3.

    DUSP1; PTPRJ; MAPK14; DHPS; Ptprr

    Blaha, M; Nemcova, L; et al. Cyclic guanosine monophosphate does not inhibit gonadotropin-induced activation of mitogen-activated protein kinase 3/1 in pig cumulus-oocyte complexes. REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY 13:-(2015).
    Chen, TC; Lin, KT; et al. Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein-Protein Interactions in a Pathway Network. JOURNAL OF PROTEOME RESEARCH 13:5339-5346(2014).

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