mapk3

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mapk3

Official Full Name MAPK3 mitogen-activated protein kinase 3
Synonyms MAPK3; mitogen-activated protein kinase 3; PRKM3; ERK1; p44erk1; p44mapk; MAPK 1; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; insulin-stimulated MAP2 kinase; mitogen-activated protein kinase 1; extracellular signal-related kinase 1; extracellular signal-regulated kinase 1; microtubule-associated protein 2 kinase; ERT2; ERK-1; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MGC20180;
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • His&GST
    • MBP
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ERK1-125H Recombinant Human MAPK3 protein, His-tagged E.coli His
    Human MAPK3-061H Recombinant Human MAPK3 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human MAPK3-1031M Recombinant Human MAPK3 protein E.coli N/A
    Human MAPK3-1048H Recombinant Human Mitogen-Activated Protein Kinase 3 (Active), GST-Tagged E.coli GST
    Human MAPK3-1049H Recombinant Human Mitogen-Activated Protein Kinase 3 (Unactive), GST-Tagged E.coli GST
    Human MAPK3-1050H Recombinant Human MAPK3 Protein, His/GST-Tagged E. coli His&GST
    Human MAPK3-1517H Recombinant Human MAPK3 protein E.coli N/A
    Human MAPK3-2787H Recombinant Human MAPK3, His-tagged E.coli His
    Human MAPK3-28694TH Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-28699TH Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-286H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-287H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-288H Recombinant Human MAPK3 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK3-28H Recombinant human biotinylated ERK1, His-tagged E.coli His
    Human MAPK3-307H Recombinant Human Mitogen-activated Protein Kinase 3, Active Sf9 Insect Cell N/A
    Human MAPK3-34H Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-36H Recombinant Human MAPK3 E.coli N/A
    Human MAPK3-4494HCL Recombinant Human MAPK3 293 Cell Lysate HEK293 N/A
    Mouse Mapk3-3942M Recombinant Mouse Mapk3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse MAPK3-9534M Recombinant Mouse MAPK3 Protein Mammalian Cell His
    Rat MAPK3-3574R Recombinant Rat MAPK3 Protein Mammalian Cell His
    Zebrafish MAPK3-11551Z Recombinant Zebrafish MAPK3 Mammalian Cell His

    mapk3 involved in several pathways and played different roles in them. We selected most pathways mapk3 participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with mapk3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FGF13B; FGF8A; TNFRSF1A; CDC42; CACNG1A; CACNA1G; FGFR1A; FGF2; MAP2K4; FGF10A
    ErbB signaling pathway MYCB; HRAS; PAK6; NCK1; RAF1; MAP2K4B; MAPK8B; SOS1; ERBB4A; NRG2B
    Ras signaling pathway PLA2G12A; HGF; PTPN11; RHOA; PIK3R3; CALM2; ANGPT2; BCL2L1; STK4; RRAS2
    Rap signaling pathway CALML5; FGF8; INS1; RAPGEF1; RALB; FGF13; FGF20; FGF4; AKT2; CALM3
    cGMP-PKG signaling pathway INS; PIK3CB; VDAC1; AKT1; MEF2C; MEF2D; CALML5; PIK3CD; SLC25A5; ATP1B4
    cAMP signaling pathway GPR81; CAMK2A; FXYD2; ATP1A4; RAP1A; PIK3R1; ACOX1; PDE4C; ORAI1; PDE4A
    Chemokine signaling pathway CCL18; GSK3A; RAF1; CCL5; RAP1B; ADRBK2; CCL20; NCF1; GNAI1; RAC2
    HIF- signaling pathway VEGFA; HKDC1; INS; ENO3; NOX3; EPO; INS2; NOS2; ERBB2; VHL
    FoxO signaling pathway MAP2K2; FOXO1B; CCNB2; PRKAA2; IGF1; BNIP3; MAPK14A; TNFSF10; INS; HRASA
    Sphingolipid signaling pathway SGMS1; CERS4; PRKCA; ACER1; GNAI1; SPHK1; PIK3R1; FYN; ROCK2; SMPD2
    Phospholipase D signaling pathway RALGDS; GRM3; MAP2K1; AGPAT4; PLA2G4D; CYTH4; CYTH2; PLCB3; PIK3R3; SHC2
    Oocyte meiosis INS; CAMK2B; PGR; YWHAZ; PRKACA; CALM2A; MAPK3; SLKA; MAPK12; PPP2CB
    mTOR signaling pathway RPS6KA3; RRAGC; EIF4E1B; CAB39L1; PIK3CA; MAPK1; RB1CC1; PRKCA; IKBKB; PRKAA1
    PIK-Akt signaling pathway LPAR2; ANGPT2; FLT4; ITGA9; IFNA2; RBL2; IFNA13; GYS2; LAMA4; GNB4
    Adrenergic signaling in cardiomyocytes ATP1A2A; ATP1A4; ADRB3B; TPM4; CALM3A; ADRB2; ACTC1B; CALM2; ATP1B1B; GNAI3
    Vascular smooth muscle contraction GNAS; PLA2G12A; PLCB1; GNA11A; AVPR1A; GNA15.4; ITPR3; PRKACG; RAF1; NPR1A
    Dorso-ventral axis formation MAP2K1; NOTCH3; CPEB2; KRAS; MAPK3; PIWIL1; CPEB4; NOTCH2; CPEB1A; CPEB3
    TGF-beta signaling pathway ACVR2AA; SKP1; ROCK2B; ACVR1L; BMPR1BA; LEFTY2; TFDP1; SMAD7; RHOAA; SP1
    Axon guidance ABLIM3; SRGAP2; ADAM10; CHL1; AP2S1; GDNF; FYN; EPHA5; NTN1B; COL4A3
    VEGF signaling pathway PIK3R5; MAPK14A; RAF1; AKT2L; PPP3R2; VEGFAA; PTK2AB; PLCG1; PIK3R2; PRKCBA
    Osteoclast differentiation NOX1; CSF1; LILRB1; LILRA1; SIRPA; MAPK3; TGFB2; PPP3R2; IL1B; TRAF6
    Focal adhesion PARVB; GSK3AA; MYL2B; PAK2A; PTENA; PAK6B; LAMC2; HRAS; AKT3A; ACTN3A
    Adherens junction MET; INSRA; WASLB; EGFR; RHOAD; PVRL3; INSRB; CTNNA3; RAC3; ACTN4
    Gap junction TUBA3B; HRASB; GNAQ; CSNK1DA; TUBA1L2; CX35B; PRKCBB; CDK1; PRKCBA; PDGFAB
    Signaling pathways regulating pluripotency of stem cells FZD5; ZIC3; MAPK3; PCGF2; SMAD2; BMPR1A; GSK3B; FGFR2; POU5F1; KLF4
    Platelet activation ACTB; PPP1CC; PIK3CG; MAPK11; PLA2G4C; PTGIR; GP5; GP1BA; PIK3R2; PIK3R1
    Toll-like receptor signaling pathway MAP2K3; CCL3L3; AKT3A; IFNAR1; MAPK12A; MAP2K6; IFNA13; CCL4L1; LY96; MAP2K2A
    NOD-like receptor signaling pathway PSTPIP1; MAPK9; RELA; MAPK12A; Ccl12; MAPK13; PSTPIP1A; MAPK12; HSP90AA1; NFKBIA
    Natural killer cell mediated cytotoxicity PLCG2; FCGR4; PIK3R5; PIK3R1; MICB; IFNA8; IFNGR2; PRF1; ZAP70; SOS1
    T cell receptor signaling pathway MAPK3; FYN; CD3D; DLG1; PAK2; IKBKB; MUC1; CD8A; RELA; IFNG
    B cell receptor signaling pathway PIK3R2; BLNK; SLA2; AKT2; DOK1B; CDK6; PTPN18; ARPC2; CD19; LILRB3
    Fc epsilon RI signaling pathway VAV2; PLA2G4D; AKT1; HRAS; AKT2; RAC3; RAC2; MS4A2; GAB2; PIK3CA
    Fc gamma R-mediated phagocytosis SPHK2; PPAP2C; PAK1; WASF1; PLA2G6; WASF2; MYO10; VAV2; PIK3R5; PRKCA
    TNF signaling pathway MAPK13; MAP3K7; MAP2K4; MLKL; MAPK1; MMP9; Ccl12; MAP3K14; MMP3; PIK3CD
    Circadian entrainment PRKACG; GRIN2C; GNAQ; CAMK2G; KCNJ6; FOS; ITPR3; RYR1; GRIN2A; GNGT1
    Long-term potentiation GNAQ; CAMK4; MAP2K1; NRAS; CAMK2A; PLCB4; GRIA1; PPP3CC; RAP1B; RPS6KA2
    Neurotrophin signaling pathway BRAF; CALML5; RHOA; RAP1A; PLCG2; CAMK2B; IRAK1; BCL2; CDC42; SHC3
    Retrograde endocannabinoid signaling GABRR1; RIMS1; PTGS2; GABRG3; PRKACB; PLCB3; GABRA4; GNB2; Adcy4; GNG8
    Glutamatergic synapse GNB4; GRIA2; HOMER1; GNG12; GLS; GRM7; MAPK1; HOMER3; GNGT2; SHANK3
    Cholinergic synapse KCNQ5; GNA11; CREB3L4; PRKCA; CREB3L1; KCNJ12; CHRM4; ITPR3; CHRNA7; KCNJ4
    Serotonergic synapse SLC6A4; GNG5; PLA2G4F; GNB1; HTR4; PLCB4; PLA2G4D; HTR2B; CYP2C38; SLC18A1
    Long-term depression GNAQ; GUCY1A3; PLCB1; GRIA2; MAPK3; PRKCB; PPP2CB; CRHR1; PPP2R1A; PPP2CA
    Regulation of actin cytoskeleton MLCK2; ITGA8; Itga10&Itgb1; ARPC4L; ARPC5A; EZR; FGFR3; BRAF; VCL; MAP2K2B
    Insulin signaling pathway PKLR; RAF1; PRKACBB; CALM1; MAPK8B; PRKAG2A; PCK1; FLOT2; RAPGEF1; SHC2
    GnRH signaling pathway PLA2G4F; MAP2K2A; PRKCBB; CALM3; PRKACG; CACNA1C; CDC42L2; PRKACAA; CACNA1SB; MAPK14B
    Progesterone-mediated oocyte maturation IGF1R; ANAPC4; MAD2L1; MAPK12A; MOS; AKT2L; GNAI2B; CPEB2; CCNB2; PRKACBB
    Estrogen signaling pathway MAP2K1; HSP90B1; PLCB4; HSPA6; MMP2; GNAQ; PLCB3; GABBR2; MAPK1; PIK3R5
    Melanogenesis WNT9A; MAP2K1; FZD10; WNT7A; CALM3A; ADCY2B; CALM3; RAF1A; CAMK2D; GNAQ
    Prolactin signaling pathway PPIB; GRB2; NFKB1; SHC2; SOCS4; AKT2; PIK3R2; MAPK10; ESR2; MAP2K2
    Thyroid hormone signaling pathway MAP2K2; BMP4; NCOA1; PLCG2; TRP53; PIK3R1; PRKCA; SLC2A1; CCND1; PLCB4
    Oxytocin signaling pathway MYLK; CACNB4; RGS2; PRKAA1; CACNG6; ACTB; PPP3R1; PPP3R2; NRAS; PPP3CA
    Type II diabetes mellitus SLC2A2; PIK3CD; PIK3R1; INS2; HK1; PIK3R3; PIK3CB; HKDC1; SOCS3; PIK3R5
    Aldosterone-regulated sodium reabsorption INS; PIK3R1; ATP1B4; HSD11B2; INS1; SGK1; INSR; IRS1; NR3C2; ALPHA-ENAC
    Alzheimers disease COX5A; COX6C; NDUFB10; ATP5B; NCSTN; MAPK3; ADAM17; BACE2; LRP1; ATP5E
    Prion diseases C8A; C1QC; C6; MAP2K2; LOC100033925; C8G; STIP1; BAX; SOD1; PRKACB
    Alcoholism HDAC8; H2AFZ; SLC18A2; CREB3L1; SOS1; GRIN1; HIST1H2BL; ADORA2B; HIST1H2BP; CREB3L4
    Shigellosis DIAPH1; MAPK11; CTTN; MAPK12; UBE2D2; PFN4; IKBKB; ACTB; BTRC; RAC1
    Salmonella infection WASF1; MAPK8A; PFN3; RAB7B; IL18; RAC1B; KLC1A; NOS2; KLC4; MAPK14B
    Pertussis IL1B; C2; IL-8; C1R; MAPK10; TICAM2; C1RA; Casp3; LY96; C1QC
    Leishmaniasis HLA-DRB3; IFNGR1; FCGR3; IFNG; NFKBIB; FCGR1A; TGFB1; FCGR1; CR1; H2-AA
    Chagas disease (American trypanosomiasis) TNFRSF1A; IFNGR2; IFNGR1; IL1B; C1QC; IFNB1; PIK3CD; CCL3L1; CD3D; PIK3R3
    Toxoplasmosis IRGM; CASP9; PIK3R2; HSPA6; NFKB1; MAP3K7; TYK2; PPIF; CD40LG; PIK3CA
    Tuberculosis TNF; IL1B; H2-AA; CD209B; PPP3CA; MAPK9; SRC; IL12A; Il23a; Il12b; FCGR3B
    Hepatitis C CLDN20; RIPK1; OAS3; KRAS; BRAF; MAPK8; RAF1; LDLR; IFNA16; AKT1
    Hepatitis B IFN-a; CCND1; CASP9; TP53; GRB2; AKT2; PIK3R3; IKBKE; MAPK8; HSPG2
    Influenza A LOC780933; TNF; MX1; IRF7; HLA-DMA; AKT1; CCL5; TNFRSF10C; HSPA1B; CASP1
    Pathways in cancer MDM2; SMAD4; SMAD2; GNG10; TRAF5; CKS2; WNT4; FZD5; PIK3CA; PRKACB
    Viral carcinogenesis DNAJA3; CCNE1; PIK3R3; SYK; PMAIP1; GTF2E2; GTF2H2C_2; H2-Q10; DLG1; MDM2
    Proteoglycans in cancer FZD6; MAPK3; Ctsl; TGFB2; PAK1; WNT16; PIK3R3; WNT5A; NRAS; PPP1R12C
    Colorectal cancer SMAD2; BCL2; MAP2K1; LEF1; MLH1; TP53; APC; RHOA; MAPK3; GSK3B
    Renal cell carcinoma TGFB3; TGFB2; MET; RAPGEF1; RBX1; PIK3CD; SLC2A1; FH; PAK3; MAPK1
    Pancreatic cancer PIK3CA; STAT3; STAT1; TP53; VEGFA; AKT2; ARAF; RAC1; PIK3R5; RAC3
    Endometrial cancer ELK1; CASP9; TP53; TCF7; MAPK3; AXIN2; PIK3CA; NRAS; PDPK1; MAP2K2
    Glioma CALM2; PRKCG; PIK3CB; PIK3CG; CALML5; HRAS; SHC2; CAMK2A; CALM3; PRKCA
    Prostate cancer CREB3L2; PDGFRB; MAPK1; FOXA1; CASP9; MAPK3; PIK3R2; SRD5A2; NRAS; ACTL6B
    Thyroid cancer NRAS; CDH1; MAPK3; TP53; PAX8; CCDC6; TPM3; MAP2K2; NCOA4; TCF7L2
    Melanoma RB1; MDM2; HRAS; FGF11; FGF22; FGF8; PIK3R1; Fgf15; MITF; FGF7
    Bladder cancer CCND1; MMP9; RAF1; E2F2; IL-8; CXCL8; ERBB2; RB1; KRAS; UPK3A
    Chronic myeloid leukemia TGFBR2; SHC3; TGFB2; CTBP2; SMAD4; PIK3CD; PIK3CB; NRAS; RB1; PTPN11
    Acute myeloid leukemia BRAF; JUP; RAF1; RUNX1; SOS1; RELA; PIK3CG; IKBKB; RPS6KB1; EIF4EBP1
    Non-small cell lung cancer TGFA; PRKCA; HRAS; FHIT; SOS1; PIK3CB; PRKCG; MAP2K1; RXRA; PLCG1
    Central carbon metabolism in cancer PFKL; SIRT3; RAF1; IDH1; HK3; PIK3CB; MTOR; FGFR3; RET; MAP2K1
    Choline metabolism in cancer LYPLA1; PLA2G4A; EGF; PIK3R2; DGKZ; PDGFB; PIP5K1A; SLC22A3; SLC44A2; RALGDS

    mapk3 has several biochemical functions, for example, ATP binding, MAP kinase activity, phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by mapk3 itself. We selected most functions mapk3 had, and list some proteins which have the same functions with mapk3. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding DDX20; NMRK1; MAPK14B; DDX49; PFKFB2; ITM2C; ACTB1; PIP5K1C; DNAJA3A; UBE2KA
    MAP kinase activity MAPK4; MAPK15; MAPK1; MAPK12A; MAPK3; MAPK8A; MAPK14; MAPK12; MAPK8B; MAPK11
    phosphatase binding MAGI2; DLG1; KLRAQ1; CTSC; PPP1R37; PPP1R26; CRY2; ELFN2; SH3RF2; MAPK3
    phosphotyrosine binding ACP2; MAPK1; FGR; CBLB; MAPK3; GRB2; PTPN3; SAMSN1; CBL; CBLC
    protein binding SKAP2; BDKRB2; ZNF473; PTPRS; DNAJB9; RAB22A; STOML2; PRKG1; PLD3; RFC3
    scaffold protein binding TREM2; CASP8; MDM2; KRT15; ATP2B4; CACNA1H; VIM; HOMER1; DSP; MAPK3

    mapk3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mapk3 here. Most of them are supplied by our site. Hope this information will be useful for your research of mapk3.

    DUSP1; PTPRJ; MAPK14; DHPS; Ptprr

    Blaha, M; Nemcova, L; et al. Cyclic guanosine monophosphate does not inhibit gonadotropin-induced activation of mitogen-activated protein kinase 3/1 in pig cumulus-oocyte complexes. REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY 13:-(2015).
    Chen, TC; Lin, KT; et al. Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein-Protein Interactions in a Pathway Network. JOURNAL OF PROTEOME RESEARCH 13:5339-5346(2014).

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