PRMT2
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Official Full Name
protein arginine methyltransferase 2
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Overview
Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene. -
Synonyms
PRMT2; protein arginine methyltransferase 2; HMT1 (hnRNP methyltransferase, S. cerevisiae) like 1 , HMT1 hnRNP methyltransferase like 1 (S. cerevisiae) , HRMT1L1; protein arginine N-methyltransferase 2; MGC111373; PRMT2 beta; PRMT2 alpha; PRMT2 gamma; HM;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- Fc
- Avi
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
PRMT2 involved in several pathways and played different roles in them. We selected most pathways PRMT2 participated on our site, such as RB in Cancer, mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRMT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RB in Cancer | RBP1;TOP2A;HLTF;SMARCA2;PRMT2;FAF1;HMGB2;DCK;ANLN |
| mRNA processing | SUGP1;HNRNPL;RBM39A;HNRNPH1;DHX15;SFPQ;EIF4E3;RNASET2B;RBM12B2 |
PRMT2 has several biochemical functions, for example, androgen receptor binding, estrogen receptor binding, histone methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRMT2 itself. We selected most functions PRMT2 had, and list some proteins which have the same functions with PRMT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| androgen receptor binding | TRIM68;EP300;SMARCA4;PRKCBB;CDK7;NSD1;PARK7;PKN1;CCNE1 |
| estrogen receptor binding | DYX1C1;ARRB1;NRIP1;XBP1;LEF1;CTNNB1;PPARG;ISL1;HSD17B10 |
| histone methyltransferase activity | PRMT1;SUV39H1;EZH2;EED;SUZ12;PRMT6;PRMT2;PRDM13;CARM1 |
| histone-arginine N-methyltransferase activity | PRMT7;PRMT2;PRMT5;PRMT3;CARM1;PRMT8;PRMT6 |
| peroxisome proliferator activated receptor binding | PPARGC1A;ASXL1;CREBBP;ASXL2;IKBKG;EP300;MED1;NFATC4;HMGA1 |
| progesterone receptor binding | NCOA1;PRMT2 |
| protein binding | HPRT1;DPYSL5;STATH;HILPDA;COG2;CSGALNACT2;RCOR1;MIF;MAST2 |
| protein homodimerization activity | USH2A;PPP2R4;NADKD1;GZMA;SNX9;MTPAP;TBX15;SLC11A1;IL17F |
| protein-arginine N-methyltransferase activity | NDUFAF5;TRMT10B;METTL7B;METTL8;PRMT3;METTL21D;CARM1;FBLL1;PRMT1 |
| protein-arginine omega-N asymmetric methyltransferase activity | PRMT2;PRMT8B;PRMT8;CARM1;PRMT1;PRMT3;PRMT7;PRMT6 |
| retinoic acid receptor binding | LRIF1;PRAMEF1;PRMT2;AASS;HMGA1-RS1;CNOT1;PRAME;HMGA1;ACTN4 |
| signal transducer activity | CRKL;HTR1D;GPR186;OLFR508;OLFR50;TAS2R130;GHRHRL;GNAO1A;CBL |
| thyroid hormone receptor binding | PRMT2;NR0B2;NCOR1;MED17;GTF2B;TRIP6;ZNHIT3;MED30;MED16 |
| transcription coactivator activity | NFE2;TAF7;SAP130;ZSCAN1;TRIM24;TRIM32;ESR2;MAX;SRA1 |
PRMT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRMT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRMT2.
ESR1; RB1; AKR1B1; PGR; NPM1; THRB; RXRA; HNRNPK
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