akr1b10
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  • Official Full Name
  • aldo-keto reductase family 1, member B10 (aldose reductase)
  • Background
  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
  • Synonyms
  • AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase); HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12; aldo-keto reductase family 1 member B10; ARP; hARP; SI reductase; aldose reductase-like 1; small intestine reductase; aldose reductase-like peptide; aldose reductase-related protein; aldo-keto reductase family 1, member B11 (aldose reductase-like);
Cat.#:AKR1B10-27154THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AKR1B10
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Cat.#:AKR1B10-27155THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AKR1B10
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Cat.#:AKR1B10-1533HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AKR1B10 protein, His & T7-tagged
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Cat.#:AKR1B10-2764HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AKR1B10, His-tagged
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Cat.#:AKR1B10-406HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AKR1B10 protein
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Cat.#:AKR1B10-410HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AKR1B10 Protein, GST-tagged
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Cat.#:AKR1B10-995HTag:Met/His
Source (Host):Baculovirus Sf21 Insect CellsSpecies:Human
Product nameRecombinant Human AKR1B10 Protein, Met & His-tagged
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Cat.#:AKR1B10-6197CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AKR1B10
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Cat.#:AKR1B10-8931HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human AKR1B10 293 Cell Lysate
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Involved Pathway

AKR1B10 involved in several pathways and played different roles in them. We selected most pathways AKR1B10 participated on our site, such as Pentose and glucuronate interconversions, Fructose and mannose metabolism, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKR1B10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pentose and glucuronate interconversions
XYLB; UGT2A2; Akr1b3; SORD; ALDH3A2A; UGT2B15; AKR1B1; UGP2; UGT1A3; DHDHL
Fructose and mannose metabolism
TPI1; ALDOA; ALDOAA; TPI1A; HK1; PFKM; AKR1B1; ENOSF1; ALDOCB; ALDOCA
Galactose metabolism
PGM2; G6PC; AKR1B1L; HK2; HK3; AKR1B8; GANC; GALT; GALK1; AKR1B10
Glycerolipid metabolism
LIPF; ALDH2; TAE1; LPL; LYCAT; ALDH9A1A.1; ALDH3A2A; PPAP2A; DGKE; AKR1A1B
Metabolic pathways
TK1; GAPDHS; AGK; WBSCR17; GLCE; PYCR1A; ST3GAL1; PTGS2; EXT1B; PDHX

Protein Function

AKR1B10 has several biochemical functions, for example, aldo-keto reductase (NADP) activity, geranylgeranyl reductase activity, indanol dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AKR1B10 itself. We selected most functions AKR1B10 had, and list some proteins which have the same functions with AKR1B10. You can find most of the proteins on our site.
Function
Related Protein
Function aldo-keto reductase (NADP) activity
Related Protein HSD3B5; SDR16C6; AKR7A3; SPR; AKR1B10; HSD3B6; H2-KE6; AKR1C3; KCNAB1; KCNAB2
Function geranylgeranyl reductase activity
Related Protein AKR1B10; AKR1C3; AKR1B8
Function indanol dehydrogenase activity
Related Protein AKR1B8; AKR1B10; AKR1C3
Function protein binding
Related Protein PIFO; SRSF2; KLF11; PTTG1IP; IRF6; FCN1; WDFY3; PLK2; CD226; CHRD
Function retinal dehydrogenase activity
Related Protein ALDH1A3; AKR1C3; AKR1C6; AKR1B8; AKR1C4; Aldh1a7; ALDH1A1; AKR1B10; ALDH8A1

Interacting Protein

AKR1B10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKR1B10 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKR1B10.
ACACA; TERF2IP; Nedd1; Jup; Slain1; TSNAX