AMH
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Official Full Name
anti-Mullerian hormone
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Overview
Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. -
Synonyms
AMH; anti-Mullerian hormone; muellerian-inhibiting factor; MIS; Anti muellerian hormone; MIF; Muellerian inhibiting factor; Mullerian inhibiting substance; anti-Muellerian hormone; Mullerian inhibiting factor; muellerian-inhibiting substance;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Bovine
- Chicken
- Human
- Mouse
- Pig
- Rat
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293 cells
- HEK293T
- Insect Cell
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- Yeast
- C
- Fc
- DDK|His
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- AMH Related Articles
AMH involved in several pathways and played different roles in them. We selected most pathways AMH participated on our site, such as cAMP signaling pathway, Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
cAMP signaling pathway | RAC2;HTR4;AKT2;CNGA4;VAV1;PIK3CD;SOX9;EP300;CALM4 |
Cytokine-cytokine receptor interaction | IFNA7;Ifna11;IFNE;PDGFRB;IFNA6;IFNA13;FLT1;BMPR2B;IFNPHI3 |
TGF-beta signaling pathway | ACVR1BA;IFNG;SMAD2;LEFTY2;SMAD1;LFT1;BMPR2;SMURF1;ROCK2B |
Hippo signaling pathway | PPP2R1B;SMAD7;LATS2;SMAD2;BMP8A;CTGF;CRB2;CCND1;PARD6A |
AMH has several biochemical functions, for example, growth factor activity, hormone activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMH itself. We selected most functions AMH had, and list some proteins which have the same functions with AMH. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
growth factor activity | THBS4;FGF10A;FGF8A;FGF12;PROK1;THPO;FGF18B;NDP;RABEP2 |
hormone activity | GH1;APLN;CGA;CSHL1;UTS2D;FNDC5;CALCA;FAM132A;PRL7A1 |
receptor binding | FYNA;MLYCD;ANG;ASIP;SERPINE1;HLA-B;SERPINE2;SNX17;HSD17B4 |
transforming growth factor beta receptor binding | GDF6B;BMP8B;GDF11;USP15;GDF15;NDR1;MSTNB;GDF6;TGFB2 |
AMH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMH here. Most of them are supplied by our site. Hope this information will be useful for your research of AMH.
ETV5; ZMAT2; ARL8B
- Q&As
- Reviews
Q&As (10)
Ask a questionAMH interacts with hormones like FSH and estrogen to modulate the balance between follicular development and follicle selection.
AMH expression is influenced by genetic variations and epigenetic modifications that can contribute to inter-individual differences in AMH levels.
AMH inhibits the development of M眉llerian ducts in males, promoting the differentiation of Sertoli cells and the formation of the male reproductive system.
Deficiency or overexpression of AMH can lead to reproductive abnormalities, such as altered fertility, impaired gonadal development, or disorders of sexual differentiation.
In females, AMH plays a role in regulating the regression of M眉llerian ducts and inhibiting follicular development.
Modulating AMH signaling pathways may hold therapeutic potential for infertility treatments and the management of reproductive disorders by manipulating follicular development or regulating reproductive organ development.
Dysregulation of AMH has been associated with reproductive disorders, including polycystic ovary syndrome (PCOS) characterized by increased AMH levels, and disorders of sexual development (DSD) associated with AMH deficiency or insensitivity.
AMH levels can serve as a valuable biomarker for assessing ovarian reserve and predicting ovarian response to fertility treatments like in vitro fertilization (IVF).
AMH expression is tightly regulated during gonadal development and sex determination, primarily controlled by the transcription factors involved in testis development, such as SRY (Sex-determining Region Y) protein.
AMH activates the transforming growth factor-beta (TGF-尾) signaling pathway, which plays a crucial role in regulating reproductive organ development and functions.
Customer Reviews (3)
Write a reviewReduced assay optimization time for faster results.
High-throughput compatibility for efficient data acquisition.
Stable reagents for long-term assay reproducibility.
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