Recombinant Chicken AMH protein, His-tagged
Cat.No. : | AMH-1764C |
Product Overview : | Recombinant Chicken AMH aa. (Thr409~Arg644) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Chicken |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 32kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Thr409~Arg644 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >96% |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200μg/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Isoelectric Point : | 7.1 |
Gene Name : | AMH anti-Mullerian hormone [ Gallus gallus (chicken) ] |
Official Symbol : | AMH |
Synonyms : | AMH; anti-Mullerian hormone; muellerian-inhibiting factor |
Gene ID : | 395887 |
mRNA Refseq : | NM_205030.1 |
Protein Refseq : | NP_990361.1 |
UniProt ID : | Q788U7 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAMH interacts with hormones like FSH and estrogen to modulate the balance between follicular development and follicle selection.
AMH expression is influenced by genetic variations and epigenetic modifications that can contribute to inter-individual differences in AMH levels.
AMH inhibits the development of M眉llerian ducts in males, promoting the differentiation of Sertoli cells and the formation of the male reproductive system.
Deficiency or overexpression of AMH can lead to reproductive abnormalities, such as altered fertility, impaired gonadal development, or disorders of sexual differentiation.
In females, AMH plays a role in regulating the regression of M眉llerian ducts and inhibiting follicular development.
Modulating AMH signaling pathways may hold therapeutic potential for infertility treatments and the management of reproductive disorders by manipulating follicular development or regulating reproductive organ development.
Dysregulation of AMH has been associated with reproductive disorders, including polycystic ovary syndrome (PCOS) characterized by increased AMH levels, and disorders of sexual development (DSD) associated with AMH deficiency or insensitivity.
AMH levels can serve as a valuable biomarker for assessing ovarian reserve and predicting ovarian response to fertility treatments like in vitro fertilization (IVF).
AMH expression is tightly regulated during gonadal development and sex determination, primarily controlled by the transcription factors involved in testis development, such as SRY (Sex-determining Region Y) protein.
AMH activates the transforming growth factor-beta (TGF-尾) signaling pathway, which plays a crucial role in regulating reproductive organ development and functions.
Customer Reviews (3)
Write a reviewReduced assay optimization time for faster results.
High-throughput compatibility for efficient data acquisition.
Stable reagents for long-term assay reproducibility.
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