Recombinant Full Length Human AMH Protein, Fc tagged

• Cat.No.: AMH-8822HFL
• Product Overview: Recombinant Full Length Human AMH Protein with Fc tag was expressed in Mammalian Cells.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Fc
• Protein Length: 1-560 aa
• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.
• Form: Lyophilized
• Molecular Mass: 85.57 kDa
• Purity: > 90% by SDS-PAGE
• Application: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for frequent use. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: AMH anti-Mullerian hormone [ Homo sapiens (human) ]
• Official Symbol: AMH
• Synonyms: AMH; anti-Mullerian hormone; MIF; MIS; muellerian-inhibiting factor; Mullerian inhibiting factor; Mullerian inhibiting substance; anti-Muellerian hormone; muellerian-inhibiting substance
• Gene ID: 268
• mRNA Refseq: NM_000479
• Protein Refseq: NP_000470
• MIM: 600957
• UniProt ID: P03971