| Species : |
Human |
| Source : |
Mammalian Cells |
| Tag : |
Fc |
| Protein Length : |
1-560 aa |
| Description : |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. |
| Form : |
Lyophilized |
| Molecular Mass : |
85.57 kDa |
| Purity : |
> 90% by SDS-PAGE |
| Application : |
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Storage : |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for frequent use. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
| Storage Buffer : |
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Shipping : |
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
