cela3b
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  • Official Full Name
  • chymotrypsin-like elastase family, member 3B
  • Background
  • Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
  • Synonyms
  • CELA3B; chymotrypsin-like elastase family, member 3B; E1; CBPP; EL-1; ELA3B; chymotrypsin-like elastase family member 3B; elastase 1; protease E; elastase-3B; proteinase E; elastase IIIB; fecal elastase 1; OTTHUMP00000002837; pancreatic elastase 1; elastase 3B, pancreatic; pancreatic endopeptidase E; cholesterol-binding pancreatic protease
Cat.#:CELA3B-2422MTag:His/Myc
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse CELA3B Protein (28-269 aa), His-Myc-tagged
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Cat.#:CELA3B-1163HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CELA3B protein, His-tagged
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Cat.#:CELA3B-256HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CELA3B protein, GST-tagged
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Cat.#:CELA3B-257HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CELA3B protein, GST-tagged
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Cat.#:CELA3B-65HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CELA3B, His-tagged
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Cat.#:Cela3b-125MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cela3b protein, His-tagged
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Cat.#:CELA3B-3271MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CELA3B Protein
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Cat.#:Cela3b-1164RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cela3b protein, His-tagged
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Cat.#:CELA3B-809RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CELA3B Protein, His-tagged
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Cat.#:CELA3B-25PTag:
Source (Host):Species:Pig
Product nameNative Porcine Elastase Protein
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Cat.#:CELA3B-7591HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CELA3B 293 Cell Lysate
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Involved Pathway

CELA3B involved in several pathways and played different roles in them. We selected most pathways CELA3B participated on our site, such as Pancreatic secretion, Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with CELA3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pancreatic secretion
PLA2G12B; ATP1B4; Slc4a2; CTRL; Adcy4; RAB3D; Car2; ATP2B4; PLA2G2A; ITPR3
Protein digestion and absorption
PGA4; ELN; SLC1A5; PRSS1; ATP1A2; SLC7A8; KCNE3; SLC1A1; SLC8A1; XPNPEP2

Protein Function

CELA3B has several biochemical functions, for example, peptidase activity, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CELA3B itself. We selected most functions CELA3B had, and list some proteins which have the same functions with CELA3B. You can find most of the proteins on our site.
Function
Related Protein
Function peptidase activity
Related Protein UNC5CL; MASP2; DHH; GM12824; METAP2B; CTS7; PROCA; METAP2A; CASPA; LTA4H
Function serine-type endopeptidase activity
Related Protein F7; TMPRSS15; CMA1; F2; MMP2; PRSS28; PCSK7; KLK1; MBTPS1; FAP