MAPK12 Protein, mitogen-activated protein kinase 12


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Official Full Name mitogen-activated protein kinase 12
Background Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
Synonyms MAPK12; mitogen-activated protein kinase 12; SAPK3; ERK6; p38gamma; PRKM12; SAPK 3; ERK-6; MAPK 12; MAP kinase 12; MAP kinase p38 gamma; stress-activated protein kinase 3; mitogen-activated protein kinase 3; extracellular signal-regulated kinase 6; mitoge
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK12-001HCL Recombinant Human MAPK12 cell lysate Insect Cell N/A
    Human MAPK12-1264H Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged Insect Cell His
    Human MAPK12-1343H Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged E.coli His
    Human MAPK12-169H Recombinant Human MAPK12 Protein, His-tagged E.coli His
    Human MAPK12-264H Recombinant Human MAPK12, Gly & Pro tagged Insect Cell His
    Human MAPK12-279H Recombinant Human MAPK12, His-GST tagged Insect Cell His
    Human MAPK12-27H Recombinant Human MAPK12 protein, GST-tagged Insect Cell GST
    Human MAPK12-30H Recombinant human biotinylated MAPK12, His-tagged E.coli His
    Human MAPK12-31377TH Recombinant Human MAPK12 N/A
    Human MAPK12-31378TH Recombinant Human MAPK12, His-tagged E.coli His
    Human MAPK12-375H Recombinant Human MAPK12, GST-tagged, Active Sf9 Insect Cell GST
    Human MAPK12-738H Recombinant Human Mitogen-activated Protein Kinase 12 E.coli N/A
    Mouse MAPK12-9528M Recombinant Mouse MAPK12 Protein Mammalian Cell His
    Rat MAPK12-3572R Recombinant Rat MAPK12 Protein Mammalian Cell His

    MAPK12 involved in several pathways and played different roles in them. We selected most pathways MAPK12 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FGF3; ELK1; NTRK2; MEF2C; NFKB1; RRAS; IL1R1; CACNA1B; MAP2K7; GRB2
    Rap signaling pathway GNAI3; ITGB2L; FGF6; PDGFB; ITGAM; PLCB2; ITGB3; FGF10; ANGPT4; KITLG
    FoxO signaling pathway CDKN2B; PCK1; CDKN1BA; PTENA; IL6; SLC2A4; TGFB2; BCL6A; GADD45BB; SMAD2
    Sphingolipid signaling pathway ASAH1; PLD1; PRKCE; RAC1; TRAF2; PPP2R1A; AKT2; SPTLC3; SMPD2; BAX
    Oocyte meiosis CALM1A; YWHAE; MAD2L1; BTRC; YWHAG1; PPP3CA; CAMK2G1; YWHAE1; ADCY1B; CDC26
    Adrenergic signaling in cardiomyocytes MAPK12; CACNG7; PPP2R2B; TPM1; VMHC; PPP2R1A; PRKACAA; ADCY7; CACNB3; CAMK2D2
    VEGF signaling pathway BAD; PPP3CA; CDC42L; RAC1B; PPP3CCA; PLCG2; KRAS; RAF1A; RAC3; MAP2K2A
    Osteoclast differentiation TNF; TNFRSF11B; LCP2; MAPK9; CYBA; MAPK8; FCGR2C; IL1B; TRAF2; LILRA5
    Signaling pathways regulating pluripotency of stem cells SMAD1; PIK3CG; MAPK13; FGFR2; GSK3B; SMARCAD1; HRAS; BMP4; ID2; BMPR1B
    Platelet activation LYN; GP5; F2RL3; FCER1G; ARHGEF1; ITPR1; PRKACG; GP6; ACTG1; P2RX1
    Toll-like receptor signaling pathway MAP3K7; IFNA14; MAP2K2B; TAB2; IL1B; IRF5; MAP2K1; IFNA3; AKT3A; TLR4
    NOD-like receptor signaling pathway NAIP1; MAPK8B; MAPK8A; CARD18; ERBB2IP; TRIP6; PSTPIP1A; CARD9; CASP5; MAPK10
    RIG-I-like receptor signaling pathway IL8L1; RNF207B; Ifna11; IFNA1; NFKBIA; TRADD; NFKB1; OTUD5; IFNA12; RIPK1
    T cell receptor signaling pathway PIK3CA; NCK1; HRAS; SLA1; CARD11; PIK3R1; CD28; PAK2; NFATC1; GRAPA
    Fc epsilon RI signaling pathway PDPK1; GRB2; RAC1; RAC3; PRKCA; HRAS; FCER1G; IL3; LAT; PIK3R5
    TNF signaling pathway VCAM1; MMP9; CREB5; MAPK3; TRAF5; MAP3K14; IL18R1; CASP7; CCL20; CXCL1
    Leukocyte transendothelial migration CLDN7; RAC1; RHOA; GNAI2; ACTN4; CLDN20; CDH5; MYL5; F11R; PIK3R5
    Neurotrophin signaling pathway CAMK2G; SORT1; PTPN11; MAGED1; CAMK2D; NGFRAP1; PIK3R3; RIPK2; AKT2; ARHGDIB
    Retrograde endocannabinoid signaling MAPK3; GABRD; MAPK13; GABRB1; GNB1; GABRR2; GABRB2; GABRG1; GABRB3; SLC17A7
    Dopaminergic synapse ATF4; CAMK2B; PPP2R1A; GNG5; PRKACG; CAMK2G; GNAL; MAPK12; DRD5; GRIA1
    Inflammatory mediator regulation of TRP channels CYP2J6; PIK3R2; CYP2C50; CYP2C55; CALM3; GNAS; CYP2C54; CALML3; PPP1CC; Adcy4
    GnRH signaling pathway ATF4; RAF1A; CDC42L; HRASB; GRB2A; PLA2G4A; SRC; NRAS; PRKACBA; CALM3A
    Progesterone-mediated oocyte maturation MAPK14B; AKT2; GNAI1; INSB; PRKACBA; MAPK8; GNAI2; INS2; RPS6KA3A; CPEB4
    Prolactin signaling pathway PIK3R2; MAPK3; SLC2A2; LHCGR; STAT1; SHC4; SIRPA; SHC1; SOCS2; TNFRSF11A
    Amyotrophic lateral sclerosis (ALS) APAF1; CAT; GRIA2; TOMM40; PPP3CA; BID; BCL2L1; GRIN2B; PRPH; BAX
    Epithelial cell signaling in Helicobacter pylori infection ATP6V1G1; ATP6V1C1; IKBKB; ATP6V1B2; MAPK11; ATP6V0C; MAPK8; CCL5; ATP6V0A4; ATP6V1A
    Salmonella infection TLR4BA; RELA; MAPK14B; PFN3; DYNC2H1; RAB7; ROCK1; ACTB2; LBP; IL8L1
    Pertussis Il23a; FOS; Itgam&Itgb2; NOS2; AMCF-II; CFL2; GM5077; NFKB1; GNAI3; NLRP3
    Leishmaniasis MAPK12; MAPK13; CR1; MAPK1; TGFB2; ITGB2; TRAF6; NFKB1; IRAK4; IL1A
    Chagas disease (American trypanosomiasis) CD247; Il2; IKBKG; PPP2CA; Fasl; IL12B; TGFB3; CALR; CCL2; GNAS
    Toxoplasmosis MAP3K7; HLA-DMB; MAPK10; MAPK8; TGFB1; STAT1; IFNG; HLA-DQB1; LAMA1; MAPK9
    Tuberculosis TRADD; MAPK11; CLEC4E; RAB5B; CALML3; ATP6V0B; BCL2; CAMK2G; RAB5C; Casp3
    Hepatitis C PPP2R2B; IFNB1; PIK3R1; IFNA17; STAT3; TNF; EIF2AK3; NR1H3; IFNAR2; BAD
    Influenza A IL12A; HLA-DQA2; EIF2AK1; TNFRSF10A; PRSS1; OAS1; BLA; PML; MAP2K1; TLR4
    Epstein-Barr virus infection EIF2AK4; ENTPD1; POLR2H; POLR2L; HLA-C; IL10RB; PSMD1; EIF2AK1; YWHAG; PLCG2
    Proteoglycans in cancer PPP1CC; ITPR1; PRKACA; GPC1; WNT1; FZD6; FZD7; ACTG1; RAF1; FZD5

    MAPK12 has several biochemical functions, for example, ATP binding, MAP kinase activity, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK12 itself. We selected most functions MAPK12 had, and list some proteins which have the same functions with MAPK12. You can find most of the proteins on our site.

    Function Related Protein
    MAP kinase activity MAPK12B; MAPK12; MAPK1; MAPK12A; MAPK7; MAPK8B; MAPK4; MAPK14A; MAPK14; NLK1
    magnesium ion binding DUT; CDC42BPG; IDH2; ITPK1; PTENA; SRPK2; ZAK; MTPAP; RRAGC; WEE2
    protein binding ANKRD27; VPS52; BDKRB2; FSTL1; BTF3; NOL9; POLD1; FCN3; S100B; SMARCC2
    protein serine/threonine kinase activity TESK1; PRKCZ; NLK1; PRKCI; ERN1; CLK2; HIPK4; CSNK1E; RPS6KC1; ROCK2B

    MAPK12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK12 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK12.


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