mapk9
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  • Official Full Name
  • MAPK9 mitogen-activated protein kinase 9
  • Background
  • Stress-activated Protein Kinases (SAPKs) are strongly activated in response to adverse stimuli such as heat and osmotic shock, UV light and other DNA-damaging reagents, and inhibitors of protein synthesis. They are also activated strongly in response to agonists that are released or produced under conditions of stress, such as proinflammatory cytokines. The SAPK1/jnk family consists of 3 isoforms:SAPK1 alpha/jnk2; SAPK1 beta/jnk3; SAPK1 beta/jnk1.
  • Synonyms
  • MAPK9; mitogen-activated protein kinase 9; PRKM9; JNK2; Jun kinase; p54a; SAPK; MAPK 9; MAP kinase 9; c-Jun kinase 2; c-Jun N-terminal kinase 2; stress-activated protein kinase 1a; stress-activated protein kinase JNK2; JNK2A; JNK2B; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA;
Cat.#:MAPK9-5488HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9
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Cat.#:MAPK9-44HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-activated Protein Kinase 9, His-tagged
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Cat.#:MAPK9-155HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAPK9 protein, His/MBP-tagged
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Cat.#:MAPK9-238HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human MAPK9 protein, His-tagged
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Cat.#:MAPK9-29670THTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human MAPK9
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Cat.#:MAPK9-45HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-activated Protein Kinase 9
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Cat.#:MAPK9-617HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human MAPK9, His tagged
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Cat.#:MAPK9-6652CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MAPK9
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Cat.#:MAPK9-1052HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9, GST-Tagged
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Cat.#:MAPK9-1265HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9
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Cat.#:MAPK9-1266HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9, His-tagged
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Cat.#:MAPK9-1267HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9
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Cat.#:MAPK9-1349HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9, His-tagged
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Cat.#:Mapk9-1053RTag:GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Mitogen-Activated Protein Kinase 9, GST-Tagged
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Cat.#:MAPK9-4485HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MAPK9 293 Cell Lysate
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Cat.#:MAPK9-4486HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MAPK9 293 Cell Lysate
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Cat.#:MAPK9-4487HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MAPK9 293 Cell Lysate
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Involved Pathway

MAPK9 involved in several pathways and played different roles in them. We selected most pathways MAPK9 participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
CACNB2A; IL1R2; MAPK4; ZAK; CACNA1C; GADD45BB; RAP1A; ATF4; GADD45G; CACNA2D4
ErbB signaling pathway
PIK3CB; RAF1B; GRB2A; GSK3B; BRAF; PAK2B; PRKCB; BTC; NRG2B; PIK3R3
Ras signaling pathway
SHC2; PIK3R1; PLA1A; ANGPT1; KITLG; PIK3R3; ANGPT4; ETS1; CALML3; FGF14
cAMP signaling pathway
VAV2; AKT1; ROCK2; GRIN2C; NPY1R; HHIP; MAPK10; FFAR2; GIPR; HTR1B
FoxO signaling pathway
FOXO6; KLF2B; TGFBR2; CCND2; PIK3R1; MAPK3; STK11; PIK3CG; MAPK8A; GRB2
Sphingolipid signaling pathway
FCER1A; TNF; AKT2; SPTLC2; NSMAF; BCL2; MAPK9; PLD2; ABCC1; ROCK1
Protein processing in endoplasmic reticulum
DAD1; HERPUD1; CANX; PRKCSH; BAX; CUL1B; SSR4; SEC24C; SELS; BCL2A
Wnt signaling pathway
WNT6; BAMBIB; WIF1; CAMK2D1; PPP3R1; RHOAA; RAC3B; CCND1; PPARD; CSNK2A2A
Osteoclast differentiation
IKBKG; NOX3; GRB2; MAPK3; CAMK4; IKBKB; IFNGR2; LILRA5; NFKBIA; TNFRSF1A
Focal adhesion
FLNC; COL5A2A; MAPK8A; STYK1; LAMB1A; PDGFA; RHOAD; CAV2; COL4A6; SHC2
Toll-like receptor signaling pathway
PIK3CB; TRAF6; IFNAR2; CRFB2; MAPK12B; MAP2K2A; IL12BA; MAPK13; CD86; TLR2-1
NOD-like receptor signaling pathway
SUGT1; CARD9; CCL2; SGUT1; HSP90AA1; LOC100033925; RIPK2; NFKBIB; MAPK12A; NAIP6
RIG-I-like receptor signaling pathway
PIN1; MAP3K1; MAPK9; RELA; IKBKB; TRAF3; IFNPHI1; PL10; IFNA7; CXCL10
T cell receptor signaling pathway
CBLB; NFKBIA; IKBKG; GRB2; SHB; PTPN6; NCK2; PDCD1; PLCG1; TNF
Fc epsilon RI signaling pathway
MAPK10; PIK3R5; GM-CSF; FYN; PIK3R2; RAC2; FCER1G; PIK3CG; PDPK1; KRAS
TNF signaling pathway
BIRC3; IKBKG; CCL2; IL1B; IL6; SOCS3; RPS6KA4; CXCL1; FAS; RIPK1
Neurotrophin signaling pathway
MAP2K2; CALM2; SH2B2; PIK3CB; ATF4; RAP1B; MAGED1; GSK3B; HRAS; PLCG2
Retrograde endocannabinoid signaling
GRM1; GNG13; MAPK10; GABRG1; GABRD; GNAI3; PLCB2; GNG11; PRKCB; GNB1
Dopaminergic synapse
PPP3CA; CALM3; GNAL; SLC18A1; DRD4; PRKCG; PPP3CB; GNAI1; GNGT2; GNGT1
Inflammatory mediator regulation of TRP channels
MAPK10; TRPV2; PRKCA; TRPV3; ASIC3; P2RY2; CAMK2D; PLA2G4A; TRPV1; HTR2C
Insulin signaling pathway
TSC2; PPP1CAA; PRKAR2B; CALM2B; RHEB; SH2B2; INSR; BRAF; MKNK2B; NRAS
GnRH signaling pathway
ELK1; ITPR1; CAMK2A; MAPK14B; CAMK2D2; PLD1A; MAP3K4; PLCB3; RAF1B; PRKCA
Progesterone-mediated oocyte maturation
PRKACAB; BUB1; FZR1; CDC25C; CDH1-A; CPEB2; KRAS; CDC26; BRAF; ANAPC5
Prolactin signaling pathway
GRB2; SOS1; INS; PPIB; MAPK12; PIK3R5; MAPK11; PIK3CB; TH; MAP2K1
Adipocytokine signaling pathway
TNFRSF1B; ACSL4A; TNF; IRS4; CHUK; ACSL1B; AKT1; ADIPOQB; G6PCA.1; PPARGC1A
Type II diabetes mellitus
INS2; MTOR; SOCS3; SOCS1; IKBKB; PIK3CA; PIK3CG; MAFA; PDX1; PIK3R3
Insulin resistance
SLC27A3; RPS6KA1; PYGB; SLC27A2; PTPN11B; FOXO1B; PRKAB1B; PRKAB1; AKT3A; PRKAG1
Non-alcoholic fatty liver disease (NAFLD)
COX8C; UQCRFS1; PRKAG2; NDUFB2; NDUFS1; NDUFB6; NDUFB10; RAC1; NDUFB9; EIF2AK3
Epithelial cell signaling in Helicobacter pylori infection
IKBKB; PLCG1; F11R; ATP6V1G3; ATP6V0C; MAPK10; CXCL1; ATP6V1H; MAPK12; ATP6V0E1
Shigellosis
MAPK9; ATG5; VCL; RHOG; NFKBIA; MAD2L2; ITGA5; PFN1; IKBKB; NFKB1
Salmonella infection
WAS; RAC1A; PKN2; KLC1; DYNC1LI2; RELA; CXCL8B.3; MAPK11; RAC1; MYD88
Pertussis
CXCL5; ITGAM; IL6; C4BPB; MAPK12; IL23; GM5077; ITGB2; AMCF-II; C2
Chagas disease (American trypanosomiasis)
TLR4; TGFB2; MAP2K4; TLR2; IL6; AKT1; CXCL8; FAS; MYD88; CCL3L1
Toxoplasmosis
HLA-DPA1; HSPA1B; HSPA8; MAPK9; IFNGR1; MAPK12; CASP8; GNAO1; Toxoplasma Gondii Major Surface Antigen P30; H2-AA
Tuberculosis
PPP3R1; FCGR3A; IFNA10; PMAP-36; IL18; FCGR2B; ITGAM; MRC2; ATP6V0D2; CLEC7A
Hepatitis C
HRAS; PPP2R2D; MAPK3; CLDN9; PPARA; CLDN4; ARAF; OAS1; SOS1; KRAS
Hepatitis B
FOS; Ifna15; ATF4; CCNE1; DDX3X; TLR2; CASP9; DDB2; PIK3R3; MMP9
Influenza A
TNF; PIK3CD; DDX39B; IL1A; IL8L1; MX1; TNFRSF10C; CXCL8; PML; NXT2
Herpes simplex infection
SRSF7; HLA-F; CASP3A; IFNA1; PPP1CAB; CUL1B; PER1A; CYCSB; HLA-DRB1; TRAF2
Epstein-Barr virus infection
POLR2H; POLR3G; PSMC1; DDX58; HSPA1B; POLR3K; HLA-A; POLR3E; H2-Q10; PSMD2
Pathways in cancer
GNAI1; FGF4; GNB3; APPL1; GNB2; RAC3; SPI1; NFKB1; TPM3; CCNA1
Colorectal cancer
PIK3CB; MAPK9; TGFBR1; RALGDS; PIK3R3; BAD; SMAD4; KRAS; CCND1; ARAF
Pancreatic cancer
NFKB1; PIK3CB; BCL2L1; TGFBR1; TGFBR2; RAF1; RALGDS; STAT3; CCND1; STAT1
Choline metabolism in cancer
KRAS; PLA2G4C; RAC3; PIP5K1C; PIK3CA; CHKB; PLA2G4D; SOS1; PCYT1A; SLC44A1

Protein Function

MAPK9 has several biochemical functions, for example, ATP binding, JUN kinase activity, cysteine-type endopeptidase activator activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK9 itself. We selected most functions MAPK9 had, and list some proteins which have the same functions with MAPK9. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CPS1; UBE2KB; TRPV1; MAPK1; MYO1C; GSK3B; PRKACAA; DAPK1; ADRBK1; OBSCN
Function JUN kinase activity
Related Protein ALPK2; MAPK10; MAPK9; MAPK8
Function cysteine-type endopeptidase activator activity involved in apoptotic process
Related Protein NOD1; GNB2L1; CASP1; RPS27L; MAPK9; BAD; CTSC; NLRP12; NLRP1; PYCARD
Function mitogen-activated protein kinase kinase kinase binding
Related Protein MAP3K11; TRAF6; CDC37; STK38; PPEF2; CDC42; TRAF2; MAPK1; MAP2K1; DUSP19
Function protein binding
Related Protein DRD1A; TRAPPC6A; CCDC12; RBM5; CALB1; PRKRIP1; KCNS2; NR2F2; PRKCB; CBL
Function transcription factor binding
Related Protein TMEM173; GTF2A1; NR0B1; SIX2; RB1; CEBPA; HEY1; LCOR; HDAC1; HDAC4

Interacting Protein

MAPK9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK9 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK9.
ARRB2; ARRB1; WDR62; SF3B4; CEP44