mapk9
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  • Official Full Name
  • MAPK9 mitogen-activated protein kinase 9
  • Background
  • Stress-activated Protein Kinases (SAPKs) are strongly activated in response to adverse stimuli such as heat and osmotic shock, UV light and other DNA-damaging reagents, and inhibitors of protein synthesis. They are also activated strongly in response to agonists that are released or produced under conditions of stress, such as proinflammatory cytokines. The SAPK1/jnk family consists of 3 isoforms:SAPK1 alpha/jnk2; SAPK1 beta/jnk3; SAPK1 beta/jnk1.
  • Synonyms
  • MAPK9; mitogen-activated protein kinase 9; PRKM9; JNK2; Jun kinase; p54a; SAPK; MAPK 9; MAP kinase 9; c-Jun kinase 2; c-Jun N-terminal kinase 2; stress-activated protein kinase 1a; stress-activated protein kinase JNK2; JNK2A; JNK2B; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA;
Cat.#:MAPK9-5488HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9
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Cat.#:MAPK9-44HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-activated Protein Kinase 9, His-tagged
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Cat.#:MAPK9-155HTag:His|MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAPK9 protein, His/MBP-tagged
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Cat.#:MAPK9-238HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human MAPK9 protein, His-tagged
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Cat.#:MAPK9-29670THTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human MAPK9
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Cat.#:MAPK9-45HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-activated Protein Kinase 9
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Cat.#:MAPK9-617HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human MAPK9, His tagged
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Cat.#:MAPK9-6652CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MAPK9
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Cat.#:MAPK9-1052HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9, GST-Tagged
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Cat.#:MAPK9-1265HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9
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Cat.#:MAPK9-1266HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9, His-tagged
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Cat.#:MAPK9-1267HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9
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Cat.#:MAPK9-1349HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase 9, His-tagged
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Cat.#:Mapk9-1053RTag:GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Mitogen-Activated Protein Kinase 9, GST-Tagged
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Cat.#:MAPK9-4485HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MAPK9 293 Cell Lysate
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Cat.#:MAPK9-4486HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MAPK9 293 Cell Lysate
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Cat.#:MAPK9-4487HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MAPK9 293 Cell Lysate
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Involved Pathway

MAPK9 involved in several pathways and played different roles in them. We selected most pathways MAPK9 participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
MAP3K6; TAOK3; GRB2; MAPK3; MEF2CB; FGFR4; CACNA1DA; RAF1; PDGFRA; TAB2
ErbB signaling pathway
AKT2L; PIK3CG; PRKCA; PRKCBA; SHC3; PIK3R5; MAP2K4; CAMK2D; MAPK1; CBLB
Ras signaling pathway
PLA2G3; SHC4; ABL2; PLD1; NGF; LOC608458; MET; FGF22; FGF19; INS2
cAMP signaling pathway
RAC1; CAMK2A; SOX9; SLC9A1; AKT2; FSHB; PAK1; PTGER3; GNAI3; PIK3R1
FoxO signaling pathway
BCL6A; IGF1R; PCK1; G6PC2; MAPK12; PLK4; PLK2B; PTENA; MAPK13; PCK2
Sphingolipid signaling pathway
BCL2; BID; MAP3K5; PPP2R1B; BDKRB2; PPP2R1A; SGPP2; FCER1A; GAB2; SPHK1
Protein processing in endoplasmic reticulum
BAG1; SEL1L; UBQLNL; SSR4; RNF185; SEL1L2; HSPA4L; MAN1C1; MAPK8; UBXN6
Wnt signaling pathway
RHOA; PPP3CCA; PRICKLE2B; RAC3A; NKD1; FZD5; NFATC1; GSK3AA; CAMK2G; PLCB2
Osteoclast differentiation
BTK; SYK; MAPK9; ACP5; LILRA3; LCK; CSF1R; CYBA; NOX3; TYROBP
Focal adhesion
COL4A6; COL1A1A; ZYX; RHOB; VASPA; MYL2; PPP1CAB; PXN; CHAD; VAV3
Toll-like receptor signaling pathway
IRF5; IFNA17; PIK3R5; AKT3A; IFNA12; IFNPHI3; STAT1A; TAB2; CCL3L1; MAPK14B
NOD-like receptor signaling pathway
MAPK8B; HSP90AA1; MAP3K7; LOC100033925; SUGT1; BIRC2; IL6; NFKB1; PSTPIP1B; CCL5
RIG-I-like receptor signaling pathway
MAPK8B; MAPK12; RELA; TP-1; IFNA21; FADD; IFNA4; RNF125; IFNW1; MAPK13
T cell receptor signaling pathway
PIK3CB; CD8B1; MAPK1; PAK7; CBLB; PIK3CA; PDPK1; PPP3R1; NFKBIB; NFKB1
Fc epsilon RI signaling pathway
PDPK1; BTK; SOS1; RAC3; RAF1; GAB2; IL5; HRAS; RAC1; AKT1
TNF signaling pathway
PIK3CB; CCL20; MAPK10; MAP2K4; TRADD; TRAF3; PIK3R1; Casp3; FAS; RPS6KA5
Neurotrophin signaling pathway
CAMK4; FOXO3; IRS1; NGFRAP1; CAMK2A; PDPK1; TP53; SHC1; RAC1; TRP53
Retrograde endocannabinoid signaling
MAPK10; MAPK9; GABRA5; GRIA2; GABRG2; GABRA3; SLC17A8; MAPK8; GNAI3; GABRD
Dopaminergic synapse
PPP2R3A; GNB1; GNAL; PPP1CB; PPP2R1A; GRIA1; MAPK10; CREB3; CALML5; PPP2R5B
Inflammatory mediator regulation of TRP channels
PLA2G4F; IL1RAP; NTRK1; PTGER2; PRKACB; ASIC1; PLA2G4D; MAPK12; CALML5; BDKRB2
Insulin signaling pathway
GRB2; TSC1A; IRS1; IKBKB; PTPN1; AKT2; FBP2; MKNK1; PHKA2; INPP5K
GnRH signaling pathway
PRKACA; GNRH3; PRKACBB; RAF1; CALM1A; MAPK14A; PRKACAB; MAP3K2; GNRHR2; MAPK11
Progesterone-mediated oocyte maturation
ARAF; CDC25A; RPS6KA1; CDC16; BUB1; MAPK13; RPS6KAL; ANAPC5; CPEB4; MAPK11
Prolactin signaling pathway
INS2; SHC3; MAPK12; PIK3R5; MAPK11; PRLR; SOS1; PRP2; MAP2K2; NEK3
Adipocytokine signaling pathway
CHUK; TNFRSF1A; SLC2A4; IRS1; JAK2B; LEPA; TRAF2; RXRA; PRKAB1; PPARA
Type II diabetes mellitus
PKLR; MAPK3; TNF; HKDC1; PIK3R5; INSR; MAPK1; MTOR; SOCS1; PDX1
Insulin resistance
PCK2; PRKCBA; PPP1CBL; PTPN11A; PRKAA2; MAPK8A; SREBF1; IKBKB; G6PC3; SLC27A4
Non-alcoholic fatty liver disease (NAFLD)
NR1H3; UQCRH; INS; KCNA3; PPARA; Casp3; AKT1; NDUFA2; CDC42; RAC1
Epithelial cell signaling in Helicobacter pylori infection
NFKBIA; ATP6V1B2; IKBKB; ATP6V0C; JAM2; ATP6V0D1; MAP2K4; LYN; MET; MAPK8
Shigellosis
NFKBIA; NFKB1; ELMO1; HCLS1; PFN3; SRC; RELA; ROCK1; PFN4; ACTG1
Salmonella infection
PFN2; PYCARD; MAPK8; WAS; MYH9; MAPK12B; MAPK12; FLNA; TLR5B; IFNGR2
Pertussis
C1S; ITGAM; PYCARD; CXCL5; CALM4; CFL2; MYD88; FOS; IRAK4; GNAI1
Chagas disease (American trypanosomiasis)
C1QB; MAPK8; Fasl; Il2; SMAD2; TGFB3; TLR6; PPP2R1A; PIK3CB; CCL3
Toxoplasmosis
BAD; MAPK11; CD40LG; HLA-DQB1; AKT1; TGFB2; RELA; IL12A; MAPK9; PIK3R1
Tuberculosis
MYD88; HLA-DRA; HLA-DQA2; CAMK2B; HLA-DQB1; HLA-DMB; AKT1; IFNA16; FCGR4; IL6
Hepatitis C
IFNA5; IFN-a; AKT1; GRB2; TRAF2; RAF1; TLR3; STAT3; BAD; TRAF6
Hepatitis B
PIK3R1; BIRC5; TICAM2; IRF7; APAF1; TLR2; MAVS; MAPK9; CREB5; MAPK1
Influenza A
PRKCA; IL6; IKBKE; IRF7; PABPN1L; HSPA1L; HLA-DOB; EIF2AK2; TMPRSS4; IRF9
Herpes simplex infection
IKBKG; MHC2A; TLR2-2; IFNGR1; IFNGR2; TAB2; NFKBIAA; HLA-DQB1; CLOCKA; NFKBIAB
Epstein-Barr virus infection
MDM2; NEDD4; STAT3; PSMC2; TBPL1; PSMD11; IFNG; H2-Q10; PIK3CB; VIM
Pathways in cancer
PTGER4; WNT5A; SLC2A1; PIK3CD; FGFR1; MMP9; BAD; FGF4; PTK2; CASP8
Colorectal cancer
CYCS; BAD; GSK3B; CCND1; TGFB3; RAC1; BAX; MLH1; AKT1; MAP2K1
Pancreatic cancer
CDC42; PIK3R2; BRCA2; MAPK10; MAPK8; CCND1; BAD; MAPK9; TGFBR2; AKT1
Choline metabolism in cancer
PLCG1; HIF1A; PIK3R2; RAC3; EIF4EBP1; SLC22A2; NRAS; DGKQ; PRKCA; PIK3CB

Protein Function

MAPK9 has several biochemical functions, for example, ATP binding, JUN kinase activity, cysteine-type endopeptidase activator activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK9 itself. We selected most functions MAPK9 had, and list some proteins which have the same functions with MAPK9. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein SNRK; JAK2; SGK196; CDK16; STRC; LACE1A; JAK1; PKM; CAMKVB; MKI67
Function JUN kinase activity
Related Protein ALPK2; MAPK9; MAPK10; MAPK8
Function cysteine-type endopeptidase activator activity involved in apoptotic process
Related Protein CASP1; CTSC; CTSH; BCL2L13; GNB2L1; NOD1; NLRP12; BAD; NLRP1; MAPK9
Function mitogen-activated protein kinase kinase kinase binding
Related Protein MAPK1; STK38; PPEF2; CDC42; DUSP19; MAP4K2; TCF3; MAPK9; MARVELD3; MAP2K1
Function protein binding
Related Protein EIF2B4; cgr2b; NAMPT; COG1; SNX33; GPS1; PARL; NOP10; SPEG; UCHL5
Function transcription factor binding
Related Protein BCL10; UBE2I; TBX5; MED12; CEBPA; KAT8; RB1; MLXIPL; PAX6; TBL1X

Interacting Protein

MAPK9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK9 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK9.
ARRB2; ARRB1; WDR62; SF3B4; CEP44