Recombinant Human Mitogen-Activated Protein Kinase 9, His-tagged

• Cat.No.: MAPK9-1266H
• Product Overview: Recombinanthuman full length MAPK9, His-tagged. Activated by coexpression with untaggedMAP2K7 and subsequently purified using Ni-NTA chromatography followed by ionexchange chromatography.

Specification

• Cat. No.: MAPK9-1266H
• Description: MAPK9is an enzyme that in humans is encoded by the MAPK9 gene.The protein encodedby this gene is a member of the MAP kinase family. MAP kinases act as anintegration point for multiple biochemical signals, and are involved in awide variety of cellular processes such as proliferation, differentiation,transcription regulation and development.
• Source: Insect cells
• Species: Human
• Form: Liquid in50 mM Tris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mMDTT + 50% glycerol.
• Molecular Weight: 52.2 kDa
• Purity: ≥ 90% as determinedby SDS-PAGE analysis
• Specific Activity: 93 nmoleof phosphate transferred to ATF2 substrate per minute per mg of total proteinat 30°C. Activity determined at a final protein concentration of 3.33 μg/ml.
• Concentration: 0.17mg/ml
• Storage: Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: MAPK9
• Function: ATP binding; JUN kinaseactivity; MAP kinase activity; nucleotide binding; protein binding; proteinserine/threonine kinase activity; transferase activity

Gene Information

• Gene Name: MAPK9mitogen-activated protein kinase 12 [ Homosapiens ]
• Synonyms: MAPK9;mitogen-activated protein kinase 9; JNK2;SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; JNK2BETA; p54aSAPK; JNK2ALPHA; Junkinase; MAP kinase 9; c-Jun kinase 2; OTTHUMP00000161542; OTTHUMP00000161543;c-Jun N-terminal kinase 2; stress-activated protein kinase JNK2;mitogen-activated protein kinase 9 isoform JNK2 alpha2; EC 2.7.11.24;Mitogen-activated protein kinase 9; Stress-activated protein kinase JNK2; OTTHUMP00000224159;OTTHUMP00000224168; OTTHUMP00000224169; OTTHUMP00000224170
• Gene ID: 5601
• mRNA Refseq: NM_001135044
• Protein Refseq: NP_001128516
• MIM: 602896
• UniProt ID: P45984
• Chromosome Location: 5q35
• Pathway: Adipocytokine signalingpathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pyloriinfection; ErbB signaling pathway; Fc epsilon RI signaling pathway; Focaladhesion; GnRH signaling pathway; Insulin signaling pathway; MAPK signalingpathway; Neurotrophin signaling pathway; Pancreatic cancer; Pathways incancer; RIG-I-like receptor signaling pathway; T cell receptor signalingpathway; Toll-like receptor signaling pathway; Type II diabetes mellitus; Wntsignaling pathway