Recombinant Human MAPK9 protein, His-tagged

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Recombinant Human MAPK9 protein, His-tagged

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Cat.No. : MAPK9-238H
Product Overview : Recombinant Human MAPK9 fused with His tag at N-terminal was expressed in E.coli.
Description : The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Source : E.coli
Species : Human
Tag : His
Form : 50mM Tris, pH8.0, 8M Urea.
Molecular Mass : 44 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : MAPK9 mitogen-activated protein kinase 9 [ Homo sapiens ]
Official Symbol : MAPK9
Synonyms : MAPK9; mitogen-activated protein kinase 9; PRKM9; JNK2; Jun kinase; p54a; SAPK; MAPK 9; MAP kinase 9; c-Jun kinase 2; c-Jun N-terminal kinase 2; stress-activated protein kinase 1a; stress-activated protein kinase JNK2; JNK2A; JNK2B; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA;
Gene ID : 5601
mRNA Refseq : NM_139069
Protein Refseq : NP_620708
MIM : 602896
UniProt ID : P45984

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