• Official Full Name
  • major vault protein
  • Background
  • This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
  • Synonyms
  • MVP; major vault protein; LRP; lung resistance related protein; VAULT1; lung resistance-related protein
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MVP Protein (2-893 aa), His-SUMO-tagged
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MVP, GST-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human MVP, MYC/DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MVP, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MVP protein, His & T7-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MVP Protein
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MVP
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MVP
Source (Host):Species:Human
Product nameRecombinant Human MVP 293 Cell Lysate

Protein Function

MVP has several biochemical functions, for example, protein binding, protein kinase binding, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MVP itself. We selected most functions MVP had, and list some proteins which have the same functions with MVP. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein C1QBP; ERP27; ARAP1; BCL2L13; GRIA2; ATXN1; PTTG1; BRCA2; HEY1; PDLIM5
Function protein kinase binding
Related Protein BCL2L14; LATS1; MAP3K13; TBL2; FBXO7; CDC42; TEX14; NEK9; AP2A2; ATG13
Function protein phosphatase binding
Related Protein HSP90B1; DRD1A; GNB2L1; PIK3R2; TP53; ROS1; MAP3K5; SKAP1; ANAPC4; DRD1

Interacting Protein

MVP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MVP here. Most of them are supplied by our site. Hope this information will be useful for your research of MVP.
PLSCR1; YWHAZ; MT-CYB; HP; EPHX2; KPNA2; CKAP4; NNT; GIT2; q7cl30_yerpe; deoB; yhdL; clpB; q81za2_bacan; POT1; q9wmx2-pro_0000037548; pi3p

MVP Related Articles

Cai, M; Zhu, F; et al. Expression, purification and glycosylation analysis of chicken infectious bursal disease virus VP2 in yeast. IRANIAN JOURNAL OF VETERINARY RESEARCH 14:211-219(2013).
Termine, C; Trotti, R; et al. Mitral valve prolapse and abnormalities of haemostasis in children and adolescents with migraine with aura and other idiopathic headaches: a pilot study. ACTA NEUROLOGICA SCANDINAVICA 122:91-96(2010).