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MVP

  • Official Full Name

    major vault protein

  • Overview

    This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
  • Synonyms

    MVP; major vault protein; LRP; lung resistance related protein; VAULT1; lung resistance-related protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MVP-1768H Recombinant Human MVP protein, His & T7-tagged E.coli His/T7 Ala2~Pro272 (Accession # Q14764)
Human MVP-1117H Recombinant Human MVP, GST-tagged E.coli GST 544-893aa
Human MVP-1115H Recombinant Human MVP, GST-tagged Wheat Germ GST
Human MVP-1116H Recombinant Human MVP, MYC/DDK-tagged HEK293 Myc/DDK
Human MVP-4050HCL Recombinant Human MVP 293 Cell Lysate HEK293 N/A
Human MVP-673H Recombinant Human MVP Protein (2-893 aa), His-SUMO-tagged E.coli His/SUMO 2-893 aa
Human MVP-6998HF Recombinant Full Length Human MVP Protein, GST-tagged In Vitro Cell Free System GST 893 amino acids
Human MVP-1131HFL Recombinant Full Length Human MVP, Flag-tagged Mamanlian cells Flag
Human MVP-998H Recombinant Human MVP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MVP-3723H Recombinant Human MVP protein, His-tagged E.coli His 544-893 aa
Human MVP-5987H Recombinant Human MVP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MVP-1081HFL Recombinant Full Length Human MVP Protein, C-Flag-tagged Mammalian cells Flag
Human MVP-1456H-B Recombinant Human MVP Protein Pre-coupled Magnetic Beads HEK293
Human MVP-5381H Recombinant Human MVP Protein (Ala2-Pro272), N-His tagged E.coli N-His Ala2-Pro272
Human MVP-1456H Recombinant Human MVP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Mvp-4230M Recombinant Mouse Mvp Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat MVP-3829R Recombinant Rat MVP Protein Mammalian Cell His
Rat MVP-3488R Recombinant Rat MVP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MVP-3488R-B Recombinant Rat MVP Protein Pre-coupled Magnetic Beads HEK293
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) RFL31092MF Recombinant Full Length Methanocaldococcus Jannaschii Hyperpolarization-Activated Voltage-Gated Potassium Channel(Mvp) Protein, His-Tagged E.coli expression system His Full Length (1-209)
Zebrafish MVP-11472Z Recombinant Zebrafish MVP Mammalian Cell His
Chicken MVP-1480C Recombinant Chicken MVP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MVP Related Articles

MVP involved in several pathways and played different roles in them. We selected most pathways MVP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MVP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MVP has several biochemical functions, for example, protein binding, protein kinase binding, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MVP itself. We selected most functions MVP had, and list some proteins which have the same functions with MVP. You can find most of the proteins on our site.

Function Related Protein
protein bindingSCHIP1;TBXA2R;TRMT112;CNTF;RAB13;MAMSTR;RPTOR;FAM13C;TWIST1
protein kinase bindingTEX14;THY1;CDK5;KAT2B;JIP1;CDC25A;GDF3;AKAP7;DNM2
protein phosphatase bindingMVP;ITGA1;JAK3;VRK3;EIF2AK3;JUP;ANAPC4;SKAP1;MET

MVP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MVP here. Most of them are supplied by our site. Hope this information will be useful for your research of MVP.

PLSCR1; YWHAZ; MT-CYB; HP; EPHX2; KPNA2; CKAP4; NNT; GIT2; q7cl30_yerpe; deoB; yhdL; clpB; q81za2_bacan; POT1; q9wmx2-pro_0000037548; pi3p

Cai, M; Zhu, F; et al. Expression, purification and glycosylation analysis of chicken infectious bursal disease virus VP2 in yeast. IRANIAN JOURNAL OF VETERINARY RESEARCH 14:211-219(2013).
Termine, C; Trotti, R; et al. Mitral valve prolapse and abnormalities of haemostasis in children and adolescents with migraine with aura and other idiopathic headaches: a pilot study. ACTA NEUROLOGICA SCANDINAVICA 122:91-96(2010).
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