Recombinant Human MVP Protein (2-893 aa), His-SUMO-tagged

• Cat.No.: MVP-673H
• Product Overview: Recombinant Human MVP Protein (2-893 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Transport. Protein Description: Full Length of Mature Protein.

Specification

• Description: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-Cytoplasmic domain transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 115.2 kDa
• Protein length: 2-893 aa
• AA Sequence: ATEEFIIRIPPYHYIHVLDQNSNVS RVEVGPKTYIRQDNERVLFAPMRMV TVPPRHYCTVANPVSRDAQGLVLFD VTGQVRLRHADLEIRLAQDPFPLYP GEVLEKDITPLQVVLPNTALHLKAL LDFEDKDGDKVVAGDEWLFEGPGTY IPRKEVEVVEIIQATIIRQNQALRL RARKECWDRDGKERVTGEEWLVTTV GAYLPAVFEEVLDLVDAVILTEKTA LHLRARRNFRDFRGVSRRTGEEWLV TVQDTEAHVPDVHEEVLGVVPITTL GPHNYCVILDPVGPDGKNQLGQKRV VKGEKSFFLQPGEQLEQGIQDVYVL SEQQGLLLRALQPLEEGEDEEKVSH QAGDHWLIRGPLEYVPSAKVEVVEE RQAIPLDENEGIYVQDVKTGKVRAV IGSTYMLTQDEVLWEKELPPGVEEL LNKGQDPLADRGEKDTAKSLQPLAP RNKTRVVSYRVPHNAAVQVYDYREK RARVVFGPELVSLGPEEQFTVLSLS AGRPKRPHARRALCLLLGPDFFTDV ITIETADHARLQLQLAYNWHFEVND RKDPQETAKLFSVPDFVGDACKAIA SRVRGAVASVTFDDFHKNSARIIRT AVFGFETSEAKGPDGMALPRPRDQA VFPQNGLVVSSVDVQSVEPVDQRTR DALQRSVQLAIEITTNSQEAAAKHE AQRLEQEARGRLERQKILDQSEAEK ARKELLELEALSMAVESTGTAKAEA ESRAEAARIEGEGSVLQAKLKAQAL AIETEAELQRVQKVRELELVYARAQ LELEVSKAQQLAEVEVKKFKQMTEA IGPSTIRDLAVAGPEMQVKLLQSLG LKSTLITDGSTPINLFNTAFGLLGM GPEGQPLGRRVASGPSPGEGISPQS AQAPQAPGDNHVVPVLR
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: MVP major vault protein [ Homo sapiens ]
• Official Symbol: MVP
• Synonyms: MVP; major vault protein; LRP; VAULT1
• Gene ID: 9961
• mRNA Refseq: NM_005115
• Protein Refseq: NP_005106
• MIM: 605088
• UniProt ID: Q14764