Recombinant Full Length Human MVP Protein, C-Flag-tagged

• Cat.No.: MVP-1081HFL
• Product Overview: Recombinant Full Length Human MVP Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 99.1 kDa
• AA Sequence: MATEEFIIRIPPYHYIHVLDQNSNV SRVEVGPKTYIRQDNERVLFAPMRM VTVPPRHYCTVANPVSRDAQ GLVLFDVTGQVRLRHADLEIRLAQD PFPLYPGEVLEKDITPLQVVLPNTA LHLKALLDFEDKDGDKVVAG DEWLFEGPGTYIPRKEVEVVEIIQA TIIRQNQALRLRARKECWDRDGKER VTGEEWLVTTVGAYLPAVFE EVLDLVDAVILTEKTALHLRARRNF RDFRGVSRRTGEEWLVTVQDTEAHV PDVHEEVLGVVPITTLGPHN YCVILDPVGPDGKNQLGQKRVVKGE KSFFLQPGEQLEQGIQDVYVLSEQQ GLLLRALQPLEEGEDEEKVS HQAGDHWLIRGPLEYVPSAKVEVVE ERQAIPLDENEGIYVQDVKTGKVRA VIGSTYMLTQDEVLWEKELP PGVEELLNKGQDPLADRGEKDTAKS LQPLAPRNKTRVVSYRVPHNAAVQV YDYREKRARVVFGPELVSLG PEEQFTVLSLSAGRPKRPHARRALC LLLGPDFFTDVITIETADHARLQLQ LAYNWHFEVNDRKDPQETAK LFSVPDFVGDACKAIASRVRGAVAS VTFDDFHKNSARIIRTAVFGFETSE AKGPDGMALPRPRDQAVFPQ NGLVVSSVDVQSVEPVDQRTRDALQ RSVQLAIEITTNSQEAAAKHEAQRL EQEARGRLERQKILDQSEAE KARKELLELEALSMAVESTGTAKAE AESRAEAARIEGEGSVLQAKLKAQA LAIETEAELQRVQKVRELEL VYARAQLELEVSKAQQLAEVEVKKF KQMTEAIGPSTIRDLAVAGPEMQVK LLQSLGLKSTLITDGSTPIN
  LFNTAFGLLGMGPEGQPLGRRVASG PSPGEGISPQSAQAPQAPGDNHVVP VLRTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: MVP major vault protein [ Homo sapiens (human) ]
• Official Symbol: MVP
• Synonyms: LRP; VAULT1
• Gene ID: 9961
• mRNA Refseq: NM_005115.5
• Protein Refseq: NP_005106.2
• MIM: 605088
• UniProt ID: Q14764