| Description : |
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
123.97 kDa |
| Protein Length : |
893 amino acids |
| AA Sequence : |
MATEEFIIRIPPYHYIHVLDQNSNV SRVEVGPKTYIRQDNERVLFAPMRM VTVPPRHYCTVANPVSRDAQGLVLF DVTGQVRLRHADLEIRLAQDPFPLY PGEVLEKDITPLQVVLPNTALHLKA LLDFEDKDGDKVVAGDEWLFEGPGT YIPRKEVEVVEIIQATIIRQNQALR LRARKECWDRDGKERVTGEEWLVTT VGAYLPAVFEEVLDLVDAVILTEKT ALHLRARRNFRDFRGVSRRTGEEWL VTVQDTEAHVPDVHEEVLGVVPITT LGPHNYCVILDPVGPDGKNQLGQKR VVKGEKSFFLQPGEQLEQGIQDVYV LSEQQGLLLRALQPLEEGEDEEKVS HQAGDHWLIRGPLEYVPSAKVEVVE ERQAIPLDENEGIYVQDVKTGKVRA VIGSTYMLTQDEVLWEKELPPGVEE LLNKGQDPLADRGEKDTAKSLQPLA PRNKTRVVSYRVPHNAAVQVYDYRE KRARVVFGPELVSLGPEEQFTVLSL SAGRPKRPHARRALCLLLGPDFFTD VITIETADHARLQLQLAYNWHFEVN DRKDPQETAKLFSVPDFVGDACKAI ASRVRGAVASVTFDDFHKNSARIIR TAVFGFETSEAKGPDGMALPRPRDQ AVFPQNGLVVSSVDVQSVEPVDQRT RDALQRSVQLAIEITTNSQEAAAKH EAQRLEQEARGRLERQKILDQSEAE KARKELLELEALSMAVESTGTAKAE AESRAEAARIEGEGSVLQAKLKAQA LAIETEAELQRVQKVRELELVYARA QLELEVSKAQQLAEVEVKKFKQMTE AIGPSTIRDLAVAGPEMQVKLLQSL GLKSTLITDGSTPINLFNTAFGLLG MGPEGQPLGRRVASGPSPGEGISPQ SAQAPQAPGDNHVVPVLR |
| Applications : |
ELISA; WB-Re; AP; Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
