| Description : |
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
99.1 kDa |
| AA Sequence : |
MATEEFIIRIPPYHYIHVLDQNSNV SRVEVGPKTYIRQDNERVLFAPMRM VTVPPRHYCTVANPVSRDAQGLVLF DVTGQVRLRHADLEIRLAQDPFPLY PGEVLEKDITPLQVVLPNTALHLKA LLDFEDKDGDKVVAGDEWLFEGPGT YIPRKEVEVVEIIQATIIRQNQALR LRARKECWDRDGKERVTGEEWLVTT VGAYLPAVFEEVLDLVDAVILTEKT ALHLRARRNFRDFRGVSRRTGEEWL VTVQDTEAHVPDVHEEVLGVVPITT LGPHNYCVILDPVGPDGKNQLGQKR VVKGEKSFFLQPGEQLEQGIQDVYV LSEQQGLLLRALQPLEEGEDEEKVS HQAGDHWLIRGPLEYVPSAKVEVVE ERQAIPLDENEGIYVQDVKTGKVRA VIGSTYMLTQDEVLWEKELPPGVEE LLNKGQDPLADRGEKDTAKSLQPLA PRNKTRVVSYRVPHNAAVQVYDYRE KRARVVFGPELVSLGPEEQFTVLSL SAGRPKRPHARRALCLLLGPDFFTD VITIETADHARLQLQLAYNWHFEVN DRKDPQETAKLFSVPDFVGDACKAI ASRVRGAVASVTFDDFHKNSARIIR TAVFGFETSEAKGPDGMALPRPRDQ AVFPQNGLVVSSVDVQSVEPVDQRT RDALQRSVQLAIEITTNSQEAAAKH EAQRLEQEARGRLERQKILDQSEAE KARKELLELEALSMAVESTGTAKAE AESRAEAARIEGEGSVLQAKLKAQA LAIETEAELQRVQKVRELELVYARA QLELEVSKAQQLAEVEVKKFKQMTE AIGPSTIRDLAVAGPEMQVKLLQSL GLKSTLITDGSTPINLFNTAFGLLG MGPEGQPLGRRVASGPSPGEGISPQ SAQAPQAPGDNHVVPVLRTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
