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Official Full Name ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Background The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are;proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the;mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to;regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that;encode different protein isoforms.
Synonyms UCHL3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin thiolesterase; ubiquitin thioesterase L3; UCH-L3
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Rabbit
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CAB11622RH Rabbit Monoclonal Antibody to Human Ubiquitin Carboxyl-Terminal Esterase L3 Rabbit N/A
    Human UCHL3-1518H Recombinant Human UCHL3, His-tagged Human His
    Human UCHL3-169H Recombinant Human UCHL3 E.coli N/A
    Human UCHL3-180H Recombinant Human UCHL3, GST-tagged E.coli GST
    Human UCHL3-3090H Recombinant Human UCHL3, His tagged E.coli His
    Human UCHL3-534HCL Recombinant Human UCHL3 293 Cell Lysate HEK293 N/A
    Mouse Uchl3-4073M Recombinant Mouse Uchl3, His tagged E.coli His
    Rat Uchl3-1810R Recombinant Rat Uchl3, His tagged E.coli His
    Rat Uchl3-609R Recombinant Rat Uchl3 Protein, His-tagged E.coli His
    Rat UCHL3-6419R Recombinant Rat UCHL3 Protein Mammalian Cell His
    Rhesus Macaque UCHL3-5086R Recombinant Rhesus monkey UCHL3 Protein, His-tagged Mammalian Cell His
    Chicken UCHL3-6388C Recombinant Chicken UCHL3 Mammalian Cell His
    Zebrafish UCHL3-3009Z Recombinant Zebrafish UCHL3 Mammalian Cell His

    UCHL3 involved in several pathways and played different roles in them. We selected most pathways UCHL3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with UCHL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome Degradation RBCK1; UBE2V2; ASB4; ASB3; HECTD3; FBXO3; ARIH2; LRSAM1; WWP1; IWS1

    UCHL3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by UCHL3 itself. We selected most functions UCHL3 had, and list some proteins which have the same functions with UCHL3. You can find most of the proteins on our site.

    Function Related Protein
    peptidase activity ELA2L; PSMA6A; AZU1; GZME; CAPN2L; MALT1; SPCS3; PSMA6B; FURIN; MPND
    protein binding IGF1; AMFR; GRK6; FIBPB; POP7; MAP2K2; PLAU; AMMECR1; MYCN; CREB3L1
    ubiquitin binding FAN1; D17WSU92E; C6orf106; KCNS1; VPS36; UBR5; SQSTM1; UBE2NB; NUP62; OTUB1
    ubiquitin-specific protease activity OTUD5A; USP37; USP40; USP12; FAM105B; DUB1; USP27X; USP48; USP43; OTUD5B

    UCHL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UCHL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of UCHL3.

    UBB; Smad1; SMAD1; COPS6; COPS5; CLPB; USP20; ATXN7L3; POGK; NSG2; pi3p

    Sarveswari, S; Vijayakumar, V; et al. Synthesis of 4-Hydroxy-2(1H)-Quinolone Derived Chalcones, Pyrazolines and Their Antimicrobial, In Silico Antimalarial Evaluations. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 175:43-64(2015).
    Hung, FF; To, WP; et al. Water-Soluble Luminescent Cyclometalated Gold(III) Complexes with cis-Chelating Bis(N-Heterocyclic Carbene) Ligands: Synthesis and Photophysical Properties. CHEMISTRY-A EUROPEAN JOURNAL 20:8604-8614(2014).

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