Recombinant Human UCHL3 Protein (E2-A230), His tagged
Cat.No. : | UCHL3-0361H |
Product Overview : | Recombinant Human 6His-TEV-GG-UCHL3(E2-A230 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3'', and exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory. Can hydrolyze UBB(+1), a mutated form of ubiquitin which is not effectively degraded by the proteasome and is associated with neurogenerative disorders. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid |
Protein Length : | E2-A230 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) [ Homo sapiens (human) ] |
Official Symbol : | UCHL3 |
Synonyms : | UCHL3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin thiolesterase; ubiquitin thioesterase L3; UCH-L3; |
Gene ID : | 7347 |
mRNA Refseq : | NM_006002 |
Protein Refseq : | NP_005993 |
MIM : | 603090 |
UniProt ID : | P15374 |
Products Types
◆ Recombinant Protein | ||
UCHL3-2303H | Recombinant Human UCHL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Uchl3-609R | Recombinant Rat Uchl3 Protein, His-tagged | +Inquiry |
UCHL3-6075R | Recombinant Rat UCHL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
UCHL3-0362H | Recombinant Human UCHL3 Protein (E2-A230), Tag Free | +Inquiry |
Uchl3-6820M | Recombinant Mouse Uchl3 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
UCHL3-534HCL | Recombinant Human UCHL3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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