adora3
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  • Official Full Name
  • adenosine A3 receptor
  • Background
  • This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • ADORA3; adenosine A3 receptor; adenosine receptor A3; AD026; A3AR; A3R; AA3R; AA3R_HUMAN; AD 026; ADORA 3; ARA3; bA552M11.5; Gpcr2; RP11 552M11.7; TGPCR1; RP11-552M11.7
Cat.#:ADORA3-371HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADORA3 Protein
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Cat.#:ADORA3-372HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADORA3 Protein, GST-tagged
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Cat.#:Adora3-3165RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Adora3, His-tagged
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Cat.#:ADORA3-535RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ADORA3 Protein
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Cat.#:ADORA3-255RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ADORA3 Protein, His-tagged
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Cat.#:ADORA3-5727CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ADORA3
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Cat.#:ADORA3-12HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADORA3 lysate
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Cat.#:Kit-1106Tag:
Source (Host):Species:
Product nameEnteropeptidase/Enterokinase Activity Fluorometric Assay Kit
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Cat.#:Kit-2177Tag:
Source (Host):Species:
Product nameADORA3 CHO-K1 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-0978Tag:
Source (Host):Species:
Product nameER Alpha Competitor Assay, Red
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Involved Pathway

ADORA3 involved in several pathways and played different roles in them. We selected most pathways ADORA3 participated on our site, such as Adenosine P1 receptors, Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADORA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adenosine P1 receptors
ADORA2B; ADORA1; ADORA2A; ADORA3
Class A/1 (Rhodopsin-like receptors)
LPAR5A; SSTR2; CXCL11.8; UTS2; RLN3; S1PR1; PENK; NMUR1; PENKA; CXCR6
G alpha (i) signalling events
CCL19A.2; RGS20; CASR; AGT; CCR8; APPB; CXCR7B; CCR1; ADRA2A; RGS10
GPCR downstream signaling
OBSCN; INSL3; OR52B4; CCR8; ADRA2C; CXCR7B; ADORA2B; APLNR; ADM2A; ADRB3
GPCR ligand binding
PTH2; CCR8; EDN2; GPR77; NMB; TRH; CHRM5; OPN1LW2; CHRM1; LPAR2A
GPCRs, Class A Rhodopsin-like
GPR85; PTGDR2; CCR1; GPR12; GPR68; DRD3; OR10A5; GPR3; SSTR4; GPR63
GPCRs, Other
GPR176; VN1R1; ADORA3; GPR77; PROKR2; OR10A5; MRGPRH; CELSR1; S1PR1; VMN1R44
Neuroactive ligand-receptor interaction
LEP; ADRB3B; NPFFR2; TAAR13B; MC5RB; TACR3L; HTR1F; TAAR14J; CNR2; Gh

Protein Function

ADORA3 has several biochemical functions, for example, G-protein coupled adenosine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADORA3 itself. We selected most functions ADORA3 had, and list some proteins which have the same functions with ADORA3. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein coupled adenosine receptor activity
Related Protein ADORA2AB; ADORA3; ADORA2AA; P2RY12; ADORA1; ADORA2B; ADORA2A

Interacting Protein

ADORA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADORA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADORA3.
ab-meca; ib-meca

ADORA3 Related Gene Family

GPCRs