ANXA5 Protein


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Official Full Name annexin A5
Background The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some;of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a;phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in;cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental;anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin;CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein;product with a molecular weight of about 35 kDa.
Synonyms ANXA5; annexin A5; ANX5, ENX2; CBP-I; PAP-I; VAC-alpha; annexin V; annexin-5; anchorin CII; endonexin II; lipocortin V; calphobindin I; thromboplastin inhibitor; vascular anticoagulant-alpha; placental anticoagulant protein 4; placental anticoagulant prot
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Cynops pyrrhogaster
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293F
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    • N-His
    • N-His&GST
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANXA5-1430H Recombinant Human Annexin A5, His-tagged E.coli His
    Human ANXA5-1124H Recombinant Human ANXA5 Protein, His-tagged Yeast His
    Human ANXA5-112H Recombinant Human ANXA5, GST-tagged E.coli GST
    Human ANXA5-19H Recombinant Human ANXA5 protein, GST-tagged E.coli GST
    Human ANXA5-2623H Recombinant Human Annexin A5, APC E.coli N/A
    Human ANXA5-2624H Recombinant Human Annexin A5, Biotin E.coli N/A
    Human ANXA5-2625H Recombinant Human Annexin A5, FITC E.coli N/A
    Human ANXA5-2626H Recombinant Human Annexin A5, PE E.coli N/A
    Human ANXA5-26600TH Recombinant Human ANXA5 protein, His-tagged E.coli His
    Human ANXA5-635H Recombinant Human ANXA5 protein, GST-tagged Wheat Germ GST
    Human ANXA5-6861H Recombinant Human ANXA5 protein E.coli
    Human ANXA5-6912H Recombinant Human Annexin A5 E.coli N/A
    Mouse ANXA5-1717M Recombinant Mouse ANXA5 Protein Mammalian Cell His
    Mouse Anxa5-324M Recombinant Mouse Anxa5 protein, His-tagged E.coli His
    Rat Anxa5-313R Recombinant Rat Anxa5 Protein, His-tagged E.coli His
    Rat Anxa5-3497R Recombinant Rat Anxa5, His-tagged E.Coli or Yeast His
    Rat ANXA5-691R Recombinant Rat ANXA5 Protein Mammalian Cell His
    Cynomolgus Monkey ANXA5-298C Recombinant Cynomolgus ANXA5 Protein, His-tagged Mammalian Cell His
    Chicken ANXA5-310C Recombinant Chicken ANXA5 Protein, His-tagged E.coli His
    Chicken ANXA5-3182C Recombinant Chicken ANXA5 Mammalian Cell His
    Human ANXA5-8830HCL Recombinant Human ANXA5 293 Cell Lysate HEK293 N/A
    Rat Anxa5-168R Recombinant Rat Anxa5 Protein, His-tagged E.coli N-His
    Human ANXA5-169H Recombinant Human ANXA5 Protein, His-tagged HEK293F N-His
    Human ANXA5-170H Recombinant Human ANXA5 Protein, His-tagged E.coli N-His
    Human ANXA5-171H Recombinant Human ANXA5 Protein, His&GST-tagged E.coli N-His&GST
    Cynops pyrrhogaster ANXA5-2521C Recombinant Cynops pyrrhogaster ANXA5 protein, His-tagged E.coli His
    Human ANXA5-001H Recombinant Human ANXA5 Protein, His-tagged E.coli His
    Human ANXA5-4705H Recombinant Human ANXA5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Anxa5-609M Recombinant Mouse Anxa5 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Anxa5-7163M Recombinant Mouse Anxa5 Protein, His-tagged E.coli His
    Chicken ANXA5-01C Recombinant Chicken ANXA5 Protein tagged Yeast

    ANXA5 involved in several pathways and played different roles in them. We selected most pathways ANXA5 participated on our site, such as Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Prostaglandin Synthesis and Regulation ANXA2; CC10; ANXA6; S100A6; S100A10; ANXA4; ANXA3; ANXA5

    ANXA5 has several biochemical functions, for example, calcium ion binding, calcium-dependent phospholipid binding, peptide hormone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA5 itself. We selected most functions ANXA5 had, and list some proteins which have the same functions with ANXA5. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PLCB1; PCDHAC2; EDEM2; S100A7; PCDH15B; PLCB3; C1rb; CABYR; EHD2; ANXA5A
    calcium-dependent phospholipid binding SYTL1; ANXA6; ANXA11; SYT12; SYT11A; SYTL4; SYT1A; ANXA8; SYT1; ANXA13
    peptide hormone binding GALR3; MC3R; AGTR1B; INHBA; NPR2; PTH1RA; MC4R; EDNRB; ANXA5; AGTR1A
    phospholipase inhibitor activity ANXA2B; ANXA1C; APOC1; ANXA1A; SNCB; ANGPTL3; ANXA4; ANXA3A; ANXA3B; ANXA1B
    phospholipid binding LPAR3; APOE; PICALMB; SPTB; DAPP1; ANXA1; ABCG1; BPIFC; NR5A2; NBEA
    protein binding ZNF625; IFNGR1; CRCP; NLRP3; MGST1; TOMM7; DNAJA2; TLX3; SMAD4; SEPT1
    receptor tyrosine kinase binding PTPN11; TOB1; FNTA; DOCK4; Flt3l; DNAJA3; NRG1; PTPN2; PLCG1; GNB2L1

    ANXA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA5.

    TINF2; Eif5b; Atrx; Bod1l1; Pds5a; Bles03; Dnmt1; yopM; FDFT1; TERF1; SUPT4H1; EIF4G1; TERF2; ispH; trmFO; TERF2IP; LAMC3; polg_hcvjf_rna

    Rogenhofer, N; Engels, L; et al. Lower Incidence of M2/ANXA5 Carriage in Recurrent Pregnancy Loss Patients With Elevated Lipoprotein(a) Levels. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 20:706-709(2014).
    Haeckel, A; Appler, F; et al. XTEN-Annexin A5: XTEN Allows Complete Expression of Long-Circulating Protein-Based Imaging Probes as Recombinant Alternative to PEGylation. JOURNAL OF NUCLEAR MEDICINE 55:508-514(2014).

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