anxa5
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  • Official Full Name
  • annexin A5
  • Background
  • The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some;of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a;phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in;cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental;anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin;CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein;product with a molecular weight of about 35 kDa.
  • Synonyms
  • ANXA5; annexin A5; ANX5, ENX2; CBP-I; PAP-I; VAC-alpha; annexin V; annexin-5; anchorin CII; endonexin II; lipocortin V; calphobindin I; thromboplastin inhibitor; vascular anticoagulant-alpha; placental anticoagulant protein 4; placental anticoagulant prot
Cat.#:ANXA5-1124HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human ANXA5 Protein, His-tagged
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Cat.#:ANXA5-26600THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA5, His-tagged
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Cat.#:ANXA5-112HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA5, GST-tagged
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Cat.#:ANXA5-19HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA5 protein, GST-tagged
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Cat.#:ANXA5-635HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ANXA5 protein, GST-tagged
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Cat.#:ANXA5-6861HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA5, None tagged
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Cat.#:ANXA5-6912HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A5
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Cat.#:ANXA5-1717MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ANXA5 Protein
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Cat.#:Anxa5-324MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Anxa5 protein, His-tagged
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Cat.#:Anxa5-313RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Anxa5 Protein, His-tagged
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Cat.#:Anxa5-3497RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Anxa5, His-tagged
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Cat.#:ANXA5-691RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ANXA5 Protein
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Cat.#:ANXA5-298CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ANXA5 Protein, His-tagged
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Cat.#:ANXA5-310CTag:His
Source (Host):E. coliSpecies:Chicken
Product nameRecombinant Chicken ANXA5 Protein, His-tagged
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Cat.#:ANXA5-3182CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ANXA5
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Cat.#:ANXA5-1430HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A5, His-tagged
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Cat.#:ANXA5-2623HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A5, APC
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Cat.#:ANXA5-2624HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A5, Biotin
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Cat.#:ANXA5-2625HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A5, FITC
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Cat.#:ANXA5-2626HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A5, PE
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Cat.#:ANXA5-8830HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ANXA5 293 Cell Lysate
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Involved Pathway

ANXA5 involved in several pathways and played different roles in them. We selected most pathways ANXA5 participated on our site, such as Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Prostaglandin Synthesis and Regulation
ANXA6; S100A10; ANXA2; S100A6; ANXA3; ANXA4; ANXA5; CC10

Protein Function

ANXA5 has several biochemical functions, for example, calcium ion binding, calcium-dependent phospholipid binding, peptide hormone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA5 itself. We selected most functions ANXA5 had, and list some proteins which have the same functions with ANXA5. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein PRKCSH; SVEP1; NOTCH2; PLA2G2A; S100A7; RCVRN; PCDH2G8; PKD2; CAPN3B; SYT17
Function calcium-dependent phospholipid binding
Related Protein DOC2B; SYT1A; PLA2G4A; ANXA2B; SYT5B; ANXA13L; SYT1; ANXA5A; C2CD4A; SYT11A
Function peptide hormone binding
Related Protein AGTR2; GALR2; MC3R; HCRTR1; ECE1; GHSR; GHR; INHBA; ANXA5; GIPR
Function phospholipase inhibitor activity
Related Protein ANGPTL3; ANXA5; ANXA2A; ANXA1B; ANXA4; APOC1; ANXA1C; ANXA1A; ANXA2B; ANXA3B
Function phospholipid binding
Related Protein BIN2; PREX1; APOEA; OSBPL1A; SMURF1; ARHGAP26; SDPR; NUP35; BAD; PTAFR
Function protein binding
Related Protein JAM3; WT1; CTCFL; PARP1; BPIFA2; ZAK; ADRBK1; APOD; HILPDA; KCTD13
Function receptor tyrosine kinase binding
Related Protein TOB1; ANGPT2; ANGPT4; PTPN1; NRG3; PTPN11; PCNA; ANGPT2A; GNB2L1; Flt3l

Interacting Protein

ANXA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA5.
TINF2; Eif5b; Atrx; Bod1l1; Pds5a; Bles03; Dnmt1; yopM; FDFT1; TERF1; SUPT4H1; EIF4G1; TERF2; ispH; trmFO; TERF2IP; LAMC3; polg_hcvjf_rna

ANXA5 Related Articles

Rogenhofer, N; Engels, L; et al. Lower Incidence of M2/ANXA5 Carriage in Recurrent Pregnancy Loss Patients With Elevated Lipoprotein(a) Levels. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 20:706-709(2014).
Haeckel, A; Appler, F; et al. XTEN-Annexin A5: XTEN Allows Complete Expression of Long-Circulating Protein-Based Imaging Probes as Recombinant Alternative to PEGylation. JOURNAL OF NUCLEAR MEDICINE 55:508-514(2014).