"C" Related Products

Recombinant Hepatitis B Virus C protein, His-tagged

Cat.No.: C -76H
Product Overview: The E.coli derived recombinant protein contains the HBV core immunodominant region amino acids 1-186, and fused to a His tag at N- terminus.
Description: Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA(pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.
Source: E. coli
Species: Hepatitis B Virus
Tag : His
Form: 25mM Tris-HCl pH-8.0, 1.5 mM EDTA, 1.5mM Urea & 50% glycerol.
Protein length: amino acids 1-186
Purity: HBV Core protein is >90% pure as determined by 10% PAGE (Coomassie staining).
Usage: The products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Specificity: Immunoreactive with sera HBV-infected individuals.
Storage: HBV Core protein although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Shipping: Ice Packs
Gene Name: C precore; HBe antigen; PreC; HBeAg; precore protein; external core antigen; HBeAg; p25 [ Hepatitis B virus ]
Official Symbol: C
Synonyms: C; precore; HBe antigen; PreC; HBeAg; precore protein; external core antigen; HBeAg; p25; pre-capsid protein; C0 uORF; capsid protein
Gene ID: 944568
Protein Refseq: YP_009173857.1
UniProt ID: P03146

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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