|Official Full Name||C-reactive protein, pentraxin-related|
|Background||The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]|
|Synonyms||CRP; C-reactive protein, pentraxin-related; PTX1; C-reactive protein; pentraxin 1;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CRP involved in several pathways and played different roles in them. We selected most pathways CRP participated on our site, such as Classical antibody-mediated complement activation, Complement cascade, Creation of C4 and C2 activators, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Classical antibody-mediated complement activation||C1rb; IgG3; CRP; IGKV1-5; IGKC; IGLC2|
|Complement cascade||GZMM; C1rb; FCN1; BFB; IGKC; CFHL3; IGLC2; CFHL1; MASP2; HBL3|
|Creation of C4 and C2 activators||FCN2; C1rb; IGKC; FCN1; IGLC2; HBL3; CRP; FCN3; IgG3; MASP2|
|IL6-mediated signaling events||JUNB; LMO4; CRP; PIAS3|
|Immune System||NOD1; LILRB5; DCTN3; LRSAM1; DUSP3; FCGR1B; BTLA; EIF4G2A; KIF22; IFI16|
|Initial triggering of complement||IgG3; MASP2; FCN2; FCN1; CRP; GZMM; FCN3; HBL3; BFB; CFD|
|Innate Immune System||TAX1BP1B; CLEC4A; CFHL3; DEFA1; FCN2; CTSK; TXNIP; CFHL2; CLEC4D; CRP|
|Selenium Pathway||SAA2; TXNRD2; CRP; SAA4; ALOX5AP; SERPINA3; SELT; PRDX2; SELK; TXNRD3IT1|
CRP has several biochemical functions, for example, calcium ion binding, choline binding, complement component C1q binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRP itself. We selected most functions CRP had, and list some proteins which have the same functions with CRP. You can find most of the proteins on our site.
|calcium ion binding||PLSCR3; AKR1C1; VSNL1A; TESCB; Npnt; PTBP3; SCUBE3; PCDH2AB2; CLEC3B; CALM3A|
|choline binding||CRP; SLC5A7; CHKA; BCHE|
|complement component C1q binding||CD93; C4A; PTX3; C1QBP; CRP; CALR; APCS|
|low-density lipoprotein particle binding||SCARF1; LDLR; SCARB1; CDH13; ANKRA2; MSR1; CRP; SORL1; PCSK9; THBS1|
|low-density lipoprotein particle receptor binding||MMP13; APOEA; SYT1; CRP; PCSK9; ARRB2; APOB; LDLRAP1; APOE; AP2M1|
|protein binding||OIP5; DAPP1; TELO2; GPX7; CD200R4; TBC1D24; PDCD2; KANK2; TBX15; TRIM43|
|NOT virion binding||CRP|
CRP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRP here. Most of them are supplied by our site. Hope this information will be useful for your research of CRP.
GMPPA; spa; FCN2; FCGR2A; FCGR2C; GLUD1; MAPK3; MAPK1; RPL13A; MAPK8IP2; DGCR14; LAMC3