CRP

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CRP

Official Full Name C-reactive protein, pentraxin-related
Background The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
Synonyms CRP; C-reactive protein, pentraxin-related; PTX1; C-reactive protein; pentraxin 1;
    • Species :
    • Canine
    • Cat
    • Cattle
    • Chicken
    • Dog
    • Equine
    • Guinea pig
    • Human
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • Canine Serum
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Human Plasma
    • Human Pleural Fluid
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Normal Rhesus Monkey Serum
    • NS0
    • Plasma
    • Rabbit Serum
    • Rat Serum
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • S
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CRP-008H Recombinant Human CRP Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human CRP-04H Recombinant Human CRP Protein, His-tagged HEK293 His
    Human CRP-111H Recombinant Human C-reactive Protein, Pentraxin-related E.coli N/A
    Human CRP-1165HCL Recombinant Human CRP cell lysate Human Cell N/A
    Human CRP-1904H Recombinant Human CRP Protein, GST-tagged Wheat Germ GST
    Human CRP-226H Recombinant Human CRP Protein NS0
    Human CRP-26069TH Recombinant Human CRP E.coli N/A
    Human CRP-26070TH Recombinant Human CRP, His-tagged E.coli His
    Human CRP-3322H Recombinant Human CRP Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CRP-4303H Native Human C-reactive Protein Human Plasma N/A
    Human CRP-508H Recombinant Human CRP Protein (Met1-Pro224), Biotinylated HEK293 N/A
    Human CRP-5299H Native Human C-Reactive Protein, Pentraxin-Related Human Pleural Fluid N/A
    Human CRP-7313H Recombinant Human CRP protein, His-tagged HEK293 His
    Human CRP-78H Human C-Reactive Protein Reference standard N/A
    Human CRP-8056H Native Human C-Reactive Protein Human Pleural Fluid N/A
    Human CRP-8057H Native C-Reactive Protein Human Pleural Fluid N/A
    Human CRP-8374H Native Human CRP Plasma N/A
    Human CRP-8544H Recombinant Human CRP, None tagged Human Cell N/A
    Human CRP-8H Human CRP Reference Standard N/A
    Human CRP-904HG GMP Recombinant Human CRP protein, His-tagged HEK293 His
    Mouse CRP-2292MCL Recombinant Mouse CRP cell lysate Human Cell N/A
    Mouse Crp-2319M Recombinant Mouse Crp Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Crp-3291M Recombinant Mouse Crp, His tagged Human Cell His
    Mouse Crp-34M Mouse C-Reactive Protein Reference Standard N/A
    Mouse Crp-7774M Recombinant Mouse Crp protein, His-tagged E.coli His
    Rat CRP-1945RCL Recombinant Rat CRP cell lysate Human Cell N/A
    Rat Crp-231R Recombinant Rat Crp protein, His-tagged Mammalian cells His
    Rat Crp-358R Recombinant Rat Crp Protein, His-tagged Insect Cell His
    Rat Crp-4095R Recombinant Rat Crp, His tagged Human Cell His
    Rat Crp-5382R Native Rat C-Reactive Protein, Petaxin Related Rat Serum N/A
    Rat Crp-75R Rat CRP Reference Standard N/A
    Rat Crp-7776R Recombinant Rat Crp protein, His & T7-tagged E.coli His/T7
    Rat CRP-8059R Native Rat Serum C-Reactive Protein Rat Serum N/A
    Rhesus Macaque CRP-159M Native Rhesus Monkey C-Reactive Protein Normal Rhesus Monkey Serum N/A
    Dog CRP-18D Dog C-Reactive Protein Reference Standard N/A
    Canine CRP-5330H Native Canine CRP protein Canine Serum N/A
    Canine CRP-59C Native Canine C-Reactive Protein Canine Serum N/A
    Rabbit CRP-158R Native Rabbit C-Reactive Protein Rabbit Serum N/A
    Chicken CRP-3391C Recombinant Chicken CRP Mammalian Cell His
    Rabbit CRP-65R Rabbit C-Reactive Protein Reference Standard N/A
    Chicken CRP-7772C Recombinant Chicken CRP protein, His & T7-tagged E.coli His/T7
    Rabbit CRP-7777R Recombinant Rabbit CRP protein, His-tagged E.coli His
    Zebrafish CRP-4437Z Recombinant Zebrafish CRP Mammalian Cell His
    Equine CRP-27H Horse C-Reactive Protein Reference Standard N/A
    Pig CRP-59P Pig C-Reactive Protein Reference Standard N/A
    Cattle CRP-7771C Recombinant Cattle CRP protein, His & T7-tagged E.coli His/T7
    Guinea pig Crp-7773G Recombinant Guinea pig Crp protein, His & S-tagged E.coli His/S
    Pig CRP-7775P Recombinant Pig CRP protein, His-tagged E.coli His
    Cat CRP-8C Cat C-Reactive Protein Reference Standard N/A

    CRP involved in several pathways and played different roles in them. We selected most pathways CRP participated on our site, such as Classical antibody-mediated complement activation, Complement cascade, Creation of C4 and C2 activators, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Classical antibody-mediated complement activation C1rb; IgG3; CRP; IGKV1-5; IGKC; IGLC2
    Complement cascade GZMM; C1rb; FCN1; BFB; IGKC; CFHL3; IGLC2; CFHL1; MASP2; HBL3
    Creation of C4 and C2 activators FCN2; C1rb; IGKC; FCN1; IGLC2; HBL3; CRP; FCN3; IgG3; MASP2
    IL6-mediated signaling events JUNB; LMO4; CRP; PIAS3
    Immune System NOD1; LILRB5; DCTN3; LRSAM1; DUSP3; FCGR1B; BTLA; EIF4G2A; KIF22; IFI16
    Initial triggering of complement IgG3; MASP2; FCN2; FCN1; CRP; GZMM; FCN3; HBL3; BFB; CFD
    Innate Immune System TAX1BP1B; CLEC4A; CFHL3; DEFA1; FCN2; CTSK; TXNIP; CFHL2; CLEC4D; CRP
    Selenium Pathway SAA2; TXNRD2; CRP; SAA4; ALOX5AP; SERPINA3; SELT; PRDX2; SELK; TXNRD3IT1

    CRP has several biochemical functions, for example, calcium ion binding, choline binding, complement component C1q binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRP itself. We selected most functions CRP had, and list some proteins which have the same functions with CRP. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PLSCR3; AKR1C1; VSNL1A; TESCB; Npnt; PTBP3; SCUBE3; PCDH2AB2; CLEC3B; CALM3A
    choline binding CRP; SLC5A7; CHKA; BCHE
    complement component C1q binding CD93; C4A; PTX3; C1QBP; CRP; CALR; APCS
    low-density lipoprotein particle binding SCARF1; LDLR; SCARB1; CDH13; ANKRA2; MSR1; CRP; SORL1; PCSK9; THBS1
    low-density lipoprotein particle receptor binding MMP13; APOEA; SYT1; CRP; PCSK9; ARRB2; APOB; LDLRAP1; APOE; AP2M1
    protein binding OIP5; DAPP1; TELO2; GPX7; CD200R4; TBC1D24; PDCD2; KANK2; TBX15; TRIM43
    NOT virion binding CRP

    CRP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRP here. Most of them are supplied by our site. Hope this information will be useful for your research of CRP.

    GMPPA; spa; FCN2; FCGR2A; FCGR2C; GLUD1; MAPK3; MAPK1; RPL13A; MAPK8IP2; DGCR14; LAMC3

    Vashist, SK; Schneider, EM; et al. Graphene-based rapid and highly-sensitive immunoassay for C-reactive protein using a smartphone-based colorimetric reader. BIOSENSORS & BIOELECTRONICS 66:169-176(2015).
    Ahmed, N; Petersson, A; et al. Tumor necrosis factor mediates temporomandibular joint bone tissue resorption in rheumatoid arthritis. ACTA ODONTOLOGICA SCANDINAVICA 73:232-240(2015).

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