Native Human C-Reactive Protein

• Cat.No.: CRP-8056H
• Product Overview: Human C-Reactive Protein was purified from Human Pleural Fluid.

Specification

• Species: Human
• Source: Human Pleural Fluid
• Tag: Non
• Description: C-Reactive Protein (CRP) is a pentameric serum protein belonging to the pentraxin family that is comprised of five identical about 23 kDa subunits. CRP is a positive acute phase reactant, the levels of which increase modestly in humans in response to inflammation, tissue injury or disease. The acute phase response develops in a wide range of acute and chronic inflammatory conditions like bacterial, viral, or fungal infections; rheumatic and other inflammatory diseases; malignancy; and tissue injury or necrosis.
• Form: Liquid solution in 0.05M Tris buffer containing 0.25M NaCl
• Molecular Mass: 115 kDa
• Purity: >98% by SDS-PAGE
• Stability: 2 years
• Storage: 2-8 °C
• Concentration: Typically >1.0 mg/mL

Gene Information

• Gene Name: CRP C-reactive protein, pentraxin-related [ Homo sapiens ]
• Official Symbol: CRP
• Synonyms: CRP; C-reactive protein, pentraxin-related; C-reactive protein; pentraxin 1; PTX1; MGC88244; MGC149895
• Gene ID: 1401
• mRNA Refseq: NM_000567
• Protein Refseq: NP_000558
• MIM: 123260
• UniProt ID: P02741
• Chromosome Location: 1q21-q23
• Pathway: Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: Gram-positive bacterial cell surface binding; binding; cholesterol binding; choline binding; low-density lipoprotein particle binding; metal ion binding; protein binding; protein homodimerization activity