EFNA3

  • Official Full Name

    ephrin-A3

  • Overview

    This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin.
  • Synonyms

    EFNA3; ephrin-A3; EPLG3; Ehk1 L; LERK3; EFL-2; LERK-3; EHK1 ligand; ligand of eph-related kinase 3; eph-related receptor tyrosine kinase ligand 3; EFL2; Ehk1-L;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Human
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • hFc
  • His
  • Fc Chimera
  • Fc|His
  • GST
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EFNA3-160H Active Recombinant Human/Cynomolgus EFNA3 protein(Gln23-Ser213), hFc-tagged HEK293 C-hFc Gln23-Ser213
Human EFNA3-3812H Active Recombinant Human Ephrin-A3 Human N/A
Human EFNA3-177H Active Recombinant Human EFNA3, Fc Chimera Mammalian cells Fc Chimera
Human EFNA3-178H Active Recombinant Human EFNA3, Fc Chimera, Biotinylated Mammalian cells Fc Chimera
Human EFNA3-196H Active Recombinant Human EFNA3 protein, hFc-tagged HEK293 hFc Met1-Ser213
Human EFNA3-28626TH Recombinant Human EFNA3 Wheat Germ N/A 238 amino acids
Human EFNA3-3151H Recombinant Human EFNA3 protein(Met1-Ser213), His-tagged HEK293 C-His Met1-Ser213
Human EFNA3-699H Active Recombinant Human EFNA3 protein(Met 1-Ser 213) HEK293 N/A Met 1-Ser 213
Human EFNA3-1609H Recombinant Human Ephrin-A3 Mammalian cells N/A
Human EFNA3-3099H Recombinant Human EFNA3 Protein, GST-tagged Wheat Germ GST
Human EFNA3-155H Active Recombinant Human EFNA3 protein, His-tagged HEK293 His Met 1-Ser 213
Human EFNA3-579H Recombinant Human ephrin-A3, His-tagged E.coli His
Human EFNA3-77H Recombinant Human EFNA3, Fc-His tagged Human Cell Fc/His
Human EFNA3-2437HCL Recombinant Human EFNA3 cell lysate Human Cell N/A
Human EFNA3-230H Recombinant Human EFNA3 Protein, His-tagged HEK293 His 238
Human EFNA3-140HF Recombinant Full Length Human EFNA3 Protein In Vitro Cell Free System 238 amino acids
Human EFNA3-182H-B Recombinant Human EFNA3 Protein Pre-coupled Magnetic Beads HEK293
Human EFNA3-4217HF Recombinant Full Length Human EFNA3 Protein, GST-tagged In Vitro Cell Free System GST 238 amino acids
Human EFNA3-182H Recombinant Human EFNA3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EFNA3-231H Recombinant Human EFNA3 Protein, Fc-tagged HEK293 Fc 238
Human EFNA3-3316H Recombinant Human EFNA3 Protein (Gln23-Ser211), C-His tagged Mammalian cells C-His Gln23-Ser211
Mouse Efna3-630M Active Recombinant Mouse Efna3 Protein, Fc Chimera Mammalian cells Fc
Mouse Efna3-4055M Active Recombinant Mouse Efna3 protein, His-tagged HEK293 His Met1-Ser205
Mouse EFNA3-2160MCL Recombinant Mouse EFNA3 cell lysate Human Cell N/A
Mouse Efna3-5643M Recombinant Mouse Efna3 Protein (Gln23-Gly206), C-Fc tagged Mammalian cells C-Fc Gln23-Gly206
Mouse Efna3-28M Recombinant Mouse Efna3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Efna3-28M-B Recombinant Mouse Efna3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EFNA3-1392R Recombinant Rhesus monkey EFNA3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EFNA3-1217R Recombinant Rhesus Macaque EFNA3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EFNA3-1217R-B Recombinant Rhesus Macaque EFNA3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

EFNA3 involved in several pathways and played different roles in them. We selected most pathways EFNA3 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFNA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceABLIM2;EPHA6;DPYSL3;NCK2;AP2A1;EPHA1;EPHB1;AP2B1;PTPRA
Developmental BiologySPAG9;NTN1B;CNTN6;KCNQ2;WDR83;EZRA;NR5A1;SDCBP;MED19
EPH-Ephrin signalingEPHA2A;EFNB3;SHB;EFNB1;EFNB3B;EFNB2A;AP2S1;EFNB2;AP2B1
EPH-ephrin mediated repulsion of cellsEFNA5;EFNB1;AP2A2;EFNB2;EFNB3B;EPHA2;CLTB;EFNA2A;EPHA2A
EPHA forward signalingEFNA3;EFNA2;EPHA2;BLK;CRKL;EFNA5;ARHGEF15;EFNA1
EPHA-mediated growth cone collapseEPHA4A;EFNA1A;EFNA1B;EFNA5;EPHA10;EFNA3;EFNA1;EFNA2;EPHA2A
MicroRNAs in cancerPRKCE;RASSF1;EZH2;HDAC1;TRP63;PLAU;SOX4;TRIM71;HOXD10
PI3K-Akt signaling pathwayLOC608458;CSF1;PIK3AP1;CSF1R;CDC37;CSH1;COMP;LAMC3;EFNA2

EFNA3 has several biochemical functions, for example, ephrin receptor binding, protein binding, transmembrane-ephrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EFNA3 itself. We selected most functions EFNA3 had, and list some proteins which have the same functions with EFNA3. You can find most of the proteins on our site.

Function Related Protein
ephrin receptor bindingEPHA7;SHC1;EFNA3B;SIPA1L1;FYN;CDK5;CRK;GRB2;EFNA2
protein bindingNBN;PPP1R12A;FAM49B;NHLRC2;ZNF576;MAP3K14;INSIG1;SMIM3;ADAM23
transmembrane-ephrin receptor activityEFNB3;EPHA10;EPHB1;EPHB2;EPHA1;EPHA5;EFNA3;EFNA4;EPHA4

EFNA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFNA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFNA3.

MEOX2; NOTCH2NL; PRSS23

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