GATA2

  • Official Full Name

    GATA binding protein 2

  • Background

    This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
  • Synonyms

    GATA2; GATA binding protein 2; DCML; IMD21; NFE1B; MONOMAC; endothelial transcription factor GATA-2;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Arg
    • Flag
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Price
    Human GATA2-28983TH Recombinant Human GATA2 Wheat Germ N/A
    Human GATA2-136H Recombinant Human GATA2 protein, Arginine-tagged E.coli Arg
    Human GATA2-476H Recombinant Human GATA2 Protein, His-tagged E.coli His
    Human GATA2-28285TH Recombinant Human GATA2 Wheat Germ N/A
    Human GATA2-6013HCL Recombinant Human GATA2 293 Cell Lysate HEK293 N/A
    Human GATA2-4745H Recombinant Human GATA2 Protein, GST-tagged Wheat Germ GST
    Human GATA2-181HF Recombinant Full Length Human GATA2 Protein In Vitro Cell Free System
    Human GATA2-962H-B Recombinant Human GATA2 Protein Pre-coupled Magnetic Beads HEK293
    Human GATA2-962H Recombinant Human GATA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human GATA2-602H Recombinant Human GATA2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human GATA2-1252HFL Recombinant Full Length Human GATA2 Protein, C-Flag-tagged Mammalian cells Flag
    Human GATA2-5465HF Recombinant Full Length Human GATA2 Protein, GST-tagged In Vitro Cell Free System GST
    Human GATA2-2792H Recombinant Human GATA2 Protein (Pro175-Gly480), His tagged E.coli His
    Mouse GATA2-6223M Recombinant Mouse GATA2 Protein Mammalian Cell His
    Mouse Gata2-477M Recombinant Mouse Gata2 Protein, His-tagged E.coli His
    Mouse GATA2-3482M-B Recombinant Mouse GATA2 Protein Pre-coupled Magnetic Beads HEK293
    Mouse Gata2-3160M Recombinant Mouse Gata2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse GATA2-3482M Recombinant Mouse GATA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Chicken GATA2-1186C Recombinant Chicken GATA2 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • GATA2 Related Articles
    • GATA2 Related Research Area

    GATA2 involved in several pathways and played different roles in them. We selected most pathways GATA2 participated on our site, such as Adipogenesis, Factors involved in megakaryocyte development and platelet production, HIF-1-alpha transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    AdipogenesisCREB1;CYP26A1;PIANP;EGR2;KLF7A;E2F1;MEF2AA;BMP3;EBF1
    Factors involved in megakaryocyte development and platelet productionGATA1;KIF3B;NFE2;DOCK6;KIFC1;DOCK9;ZFPM1;IRF1B;HBG2
    HIF-1-alpha transcription factor networkTFF3;ENG;CP;NPM1;GATA2;ADM;PLIN2;COPS5;NDRG1
    HemostasisRHOGA;CAP1;SERPINB8;HBBE3;F13A1B;GRB7;CXADR;ESAMA;CFD
    IL-3 Signaling PathwayKCNIP3;SPI1B;GATA2A;GATA1;CISH;BMX;GATA1A;PILRB;GSK3AB
    Regulation of Androgen receptor activityNR2C1;KAT7;NR2C2;SRY;APPBP2;SENP1;SMARCA2;TRIM24;GATA2
    SIDS Susceptibility PathwaysCTCF;MBD1;POU2F2;CHRFAM7A;KCNH2;CREM;KCNJ8;ECE1;RUNX3
    Signaling events mediated by HDAC Class INR2C1;PRMT5;TFCP2;MXD1;GATA2;SIRT2;FKBP3;WDR77;SIRT7

    GATA2 has several biochemical functions, for example, C2H2 zinc finger domain binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GATA2 itself. We selected most functions GATA2 had, and list some proteins which have the same functions with GATA2. You can find most of the proteins on our site.

    Function Related Protein
    C2H2 zinc finger domain bindingWT1;HMGA2;GATA2;EBF1;GATA1;LEF1;EHMT2;U2AF2;EHMT1
    RNA polymerase II distal enhancer sequence-specific DNA bindingREL;BACH1A;GZF1;HNRNPC;CREB1;NR5A2;SFPI1;SIX3;FLI1
    RNA polymerase II regulatory region sequence-specific DNA bindingDBP;MYOG;SNAI1;GLIS1;RXRA;PHF21B;CREB3;SATB1;TBX20
    RNA polymerase II transcription factor bindingMTA2;DHX9;WWP2;ID4;SPOP;KDM1A;Ar;ZFPM2A;GSC
    chromatin bindingTMPOA;SMARCD1;UBTF;ZMYND11;FOXO1;ARX;TOX4;WHSC1;EGR2
    enhancer sequence-specific DNA bindingGATA2;MYT1;SOX11;LDB1;ATF2;HMGB2;ISL1;XBP1;TFAP2B
    protein bindingDYNC1LI1;CDKN2B;LIMK1;RHPN1;CTNNA3;STX7;ATRNL1;MAPK3;RASSF2
    transcription factor activity, sequence-specific DNA bindingETS2;TGIF1;MYCB;RERE;ZFP28;PRDM1;Ar;FOXJ1B;WNT5A
    transcription factor bindingCXXC5;DAXX;PARK7;NEUROD1;RNF222;ERCC3;PPARGC1A;MDFI;DR1
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingNFATC3;POU1F1;ESR1;NKX2-8;PATZ1;MYC;MITF;MYOCD;OTX1
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingMAFGA;MAFF;MYOCD;ATF1;CREBBP;MAFBA;EAF2;HOXD8;ATF3
    zinc ion bindingISL1L;GATA1A;PRICKLE2B;NAPEPLD;CAD;APOBEC2A;TRIM39;CPA2;TRAF4

    GATA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GATA2.

    Lmo2; PSMA3; TRIM23; KRTAP10-9; PRR20C; GOLGA2

    Plymate, SR; Bhatt, RS; et al. Taxane Resistance in Prostate Cancer Mediated by AR-Independent GATA2 Regulation of IGF2. CANCER CELL 27:158-159(2015).
    Chou, J; Lutskiy, M; et al. Presence of hypogammaglobulinemia and abnormal antibody responses in GATA2 deficiency. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 134:223-226(2014).
    • Q&As
    • Reviews

    Q&As (0)

    Ask a question

    Customer Reviews (0)

    Write a review

    Ask a Question for All GATA2 Products

    Required fields are marked with *

    My Review for All GATA2 Products

    Required fields are marked with *

    logo

    Stay Updated on the
    Latest Bioscience Trends

    Copyright © 2023 Creative BioMart. All Rights Reserved.

    Terms and Conditions        Privacy Policy