|Official Full Name||glycogen synthase kinase 3 alpha|
|Background||This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimers disease. [provided by RefSeq, Oct 2011]|
|Synonyms||GSK3A; glycogen synthase kinase 3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
gsk3a involved in several pathways and played different roles in them. We selected most pathways gsk3a participated on our site, such as Chemokine signaling pathway, Dopaminergic synapse, Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with gsk3a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Chemokine signaling pathway||LYN; VAV1; GNB4; GRK6; CX3CR1; RLN1; PAK1; GRK4; PIK3R3; GNG13|
|Dopaminergic synapse||CALML5; SLC6A3; GNAQ; ARRB2; COMT; PPP2R5E; CALML3; ITPR3; PPP3CC; CAMK2B|
|Non-alcoholic fatty liver disease (NAFLD)||PIK3R5; NDUFB3; LEP; NDUFB4; COX6A2; NDUFS4; NDUFA2; GSK3A; COX7A2L; NDUFV1|
gsk3a has several biochemical functions, for example, ATP binding, protein binding, protein kinase A catalytic subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gsk3a itself. We selected most functions gsk3a had, and list some proteins which have the same functions with gsk3a. You can find most of the proteins on our site.
|ATP binding||MTHFS; BBS10; PRKAG2; SMC3; NADK; ITM2C; CCT8; DDX39AA; MINK1; RPS6KA3B|
|protein binding||NKX2-5; SENP6; TCTEX1D1; UPRT; ATP5F1; ZCCHC13; UBE2I; C9orf24; KLF10; LZTS2|
|protein kinase A catalytic subunit binding||PRKAR1B; GSK3A; PRKAR2B; GSK3B; PRKAR2A; CSK; PRKAR1A; RYR2; PKIA; EZR|
|protein serine/threonine kinase activity||MAP3K11; RPS6KA5; PKN1; TTBK2; NIM1K; MAPK8B; MARK2; PIK3CG; NEK3; CDC42BPB|
|tau-protein kinase activity||PRKAA1; MARK4; MARK2; PHKG1; CDK5; GSK3A; MARK1; CSNK1D; GSK3B; PHKG2|
gsk3a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gsk3a here. Most of them are supplied by our site. Hope this information will be useful for your research of gsk3a.
YWHAG; AXIN1; GSKIP; FRAT1; DEAF1; LRP6; HSP90AB1; ZDHHC17; saicar; APP