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Official Full Name glycogen synthase kinase 3 alpha
Background This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimers disease. [provided by RefSeq, Oct 2011]
Synonyms GSK3A; glycogen synthase kinase 3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A;
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • S.frugiperda
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GSK3A-055H Recombinant Human GSK3A Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human GSK3A-1133H Recombinant Human Glycogen Synthase Kinase 3 Alpha E.coli N/A
    Human GSK3A-1234H Recombinant Human Glycogen Synthase Kinase 3 Alpha, His-tagged Insect Cell His
    Human GSK3A-13561H Recombinant Human GSK3A, GST-tagged E.coli GST
    Human GSK3A-1411H Recombinant Human GSK3 alpha (Active), GST-tagged Sf9 Insect Cell GST
    Human GSK3A-2648H Recombinant Human GSK3A, GST-tagged S.frugiperda GST
    Human GSK3A-325H Recombinant Human GSK3A, GST-tagged, Active Sf9 Insect Cell GST
    Human GSK3A-4397H Recombinant Human GSK3A Protein, GST-tagged Wheat Germ GST
    Human GSK3A-5723HCL Recombinant Human GSK3A 293 Cell Lysate HEK293 N/A
    Human GSK3A-634H Recombinant Human GSK3A protein, His & GST-tagged E.coli His/GST
    Mouse Gsk3a-3317M Recombinant Mouse Gsk3a Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Gsk3a-635M Recombinant Mouse Gsk3a protein, His & T7-tagged E.coli His/T7
    Mouse GSK3A-7317M Recombinant Mouse GSK3A Protein Mammalian Cell His
    Rat GSK3A-2727R Recombinant Rat GSK3A Protein Mammalian Cell His
    Rat Gsk3a-636R Recombinant Rat Gsk3a protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque GSK3A-1984R Recombinant Rhesus monkey GSK3A Protein, His-tagged Mammalian Cell His

    gsk3a involved in several pathways and played different roles in them. We selected most pathways gsk3a participated on our site, such as Chemokine signaling pathway, Dopaminergic synapse, Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with gsk3a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemokine signaling pathway LYN; VAV1; GNB4; GRK6; CX3CR1; RLN1; PAK1; GRK4; PIK3R3; GNG13
    Dopaminergic synapse CALML5; SLC6A3; GNAQ; ARRB2; COMT; PPP2R5E; CALML3; ITPR3; PPP3CC; CAMK2B
    Non-alcoholic fatty liver disease (NAFLD) PIK3R5; NDUFB3; LEP; NDUFB4; COX6A2; NDUFS4; NDUFA2; GSK3A; COX7A2L; NDUFV1

    gsk3a has several biochemical functions, for example, ATP binding, protein binding, protein kinase A catalytic subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gsk3a itself. We selected most functions gsk3a had, and list some proteins which have the same functions with gsk3a. You can find most of the proteins on our site.

    Function Related Protein
    protein binding NKX2-5; SENP6; TCTEX1D1; UPRT; ATP5F1; ZCCHC13; UBE2I; C9orf24; KLF10; LZTS2
    protein kinase A catalytic subunit binding PRKAR1B; GSK3A; PRKAR2B; GSK3B; PRKAR2A; CSK; PRKAR1A; RYR2; PKIA; EZR
    protein serine/threonine kinase activity MAP3K11; RPS6KA5; PKN1; TTBK2; NIM1K; MAPK8B; MARK2; PIK3CG; NEK3; CDC42BPB
    tau-protein kinase activity PRKAA1; MARK4; MARK2; PHKG1; CDK5; GSK3A; MARK1; CSNK1D; GSK3B; PHKG2

    gsk3a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gsk3a here. Most of them are supplied by our site. Hope this information will be useful for your research of gsk3a.


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