Recombinant Human GSK3A Protein, GST-tagged
Cat.No. : | GSK3A-4397H |
Product Overview : | Human GSK3A full-length ORF (AAH27984.1, 1 a.a. - 483 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | Glycogen synthase kinase 3-alpha (GSK3A; EC {2.7.1.37}) is a multifunctional protein serine kinase, homologous to Drosophila shaggy (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase (see GYS1, {138570}) and transcription factors (e.g., JUN, {165160}). It also plays a role in the WNT ({164820}) and PI3K (see PIK3CG, {601232}) signaling pathways (see review by {1:Ali et al. (2001)}).[supplied by OMIM |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 77.4 kDa |
AA Sequence : | MSGGGPSGGGPGGSGRARTSSFAEP GGGGGGGGGGPGGSASGPGGTGGGK ASVGAMGGGVGASSSGGGPGGSGGG GSGGPGAGTSFPPPGVKLGRDSGKV TTVVATLGQGPERSQEVAYTDIKVI GNGSFGVVYQARLAETRELVAIKKV LQDKRFKNRELQIMRKLDHCNIVRL RYFFYSSGEKKDELYLNLVLEYVPE TVYRVARHFTKAKLTIPILYVKVYM YQLFRSLAYIHSQGVCHRDIKPQNL LVDPDTAVLKLCDFGSAKQLVRGEP NVSYICSRYYRAPELIFGATDYTSS IDVWSAGCVLAELLLGQPIFPGDSG VDQLVEIIKVLGTPTREQIREMNPN YTEFKFPQIKAHPWTKVFKSRTPPE AIALCSSLLEYTPSSRLSPLEACAH SFFDELRCLGTQLPNNRPLPPLFNF SAGELSIQPSLNAILIPPHLRSPAG TTTLTPSSQALTETPTSSDWQSTDA TPTLTNSS |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GSK3A glycogen synthase kinase 3 alpha [ Homo sapiens ] |
Official Symbol : | GSK3A |
Synonyms : | GSK3A; glycogen synthase kinase 3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A; DKFZp686D0638; |
Gene ID : | 2931 |
mRNA Refseq : | NM_019884 |
Protein Refseq : | NP_063937 |
MIM : | 606784 |
UniProt ID : | P49840 |
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◆ Lysates | ||
GSK3A-5723HCL | Recombinant Human GSK3A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewIts high purity and integrity ensure reliable and reproducible results, minimizing any potential variability in my experimental outcomes.
This aspect is crucial in maintaining the scientific rigor of my studies and strengthens the validity of my research findings.
the manufacturer's commitment to continuous improvement and innovation is evident in their constant efforts to enhance the GSK3A protein.
Q&As (5)
Ask a questionGSK3A is implicated in insulin signaling and glucose metabolism, and its dysregulation is associated with insulin resistance, a key feature of type 2 diabetes.
Yes, GSK3A is implicated in pathways associated with mood regulation, and inhibitors are being investigated for their potential in treating mood disorders.
Yes, there is ongoing research to develop GSK3A modulators as potential anti-inflammatory agents.
GSK3A is involved in inflammatory signaling pathways, and its activity is linked to the regulation of inflammatory responses.
Researchers are investigating the potential of GSK3A inhibitors to improve insulin sensitivity and glucose homeostasis in diabetes.
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