Recombinant Human GSK3A Protein, GST-tagged

Cat.No. : GSK3A-4397H
Product Overview : Human GSK3A full-length ORF (AAH27984.1, 1 a.a. - 483 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : Glycogen synthase kinase 3-alpha (GSK3A; EC {2.7.1.37}) is a multifunctional protein serine kinase, homologous to Drosophila shaggy (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase (see GYS1, {138570}) and transcription factors (e.g., JUN, {165160}). It also plays a role in the WNT ({164820}) and PI3K (see PIK3CG, {601232}) signaling pathways (see review by {1:Ali et al. (2001)}).[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 77.4 kDa
AA Sequence : MSGGGPSGGGPGGSGRARTSSFAEP GGGGGGGGGGPGGSASGPGGTGGGK ASVGAMGGGVGASSSGGGPGGSGGG GSGGPGAGTSFPPPGVKLGRDSGKV TTVVATLGQGPERSQEVAYTDIKVI GNGSFGVVYQARLAETRELVAIKKV LQDKRFKNRELQIMRKLDHCNIVRL RYFFYSSGEKKDELYLNLVLEYVPE TVYRVARHFTKAKLTIPILYVKVYM YQLFRSLAYIHSQGVCHRDIKPQNL LVDPDTAVLKLCDFGSAKQLVRGEP NVSYICSRYYRAPELIFGATDYTSS IDVWSAGCVLAELLLGQPIFPGDSG VDQLVEIIKVLGTPTREQIREMNPN YTEFKFPQIKAHPWTKVFKSRTPPE AIALCSSLLEYTPSSRLSPLEACAH SFFDELRCLGTQLPNNRPLPPLFNF SAGELSIQPSLNAILIPPHLRSPAG TTTLTPSSQALTETPTSSDWQSTDA TPTLTNSS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GSK3A glycogen synthase kinase 3 alpha [ Homo sapiens ]
Official Symbol : GSK3A
Synonyms : GSK3A; glycogen synthase kinase 3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A; DKFZp686D0638;
Gene ID : 2931
mRNA Refseq : NM_019884
Protein Refseq : NP_063937
MIM : 606784
UniProt ID : P49840

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
08/12/2020

    Its high purity and integrity ensure reliable and reproducible results, minimizing any potential variability in my experimental outcomes.

    09/18/2019

      This aspect is crucial in maintaining the scientific rigor of my studies and strengthens the validity of my research findings.

      04/10/2019

        the manufacturer's commitment to continuous improvement and innovation is evident in their constant efforts to enhance the GSK3A protein.

        Q&As (5)

        Ask a question
        In what ways is GSK3A linked to diabetes? 09/27/2021

        GSK3A is implicated in insulin signaling and glucose metabolism, and its dysregulation is associated with insulin resistance, a key feature of type 2 diabetes.

        Can GSK3A inhibitors have an impact on mood disorders? 11/16/2019

        Yes, GSK3A is implicated in pathways associated with mood regulation, and inhibitors are being investigated for their potential in treating mood disorders.

        Are there GSK3A modulators being explored for anti-inflammatory therapies? 08/28/2019

        Yes, there is ongoing research to develop GSK3A modulators as potential anti-inflammatory agents.

        How does GSK3A contribute to inflammatory conditions? 04/25/2017

        GSK3A is involved in inflammatory signaling pathways, and its activity is linked to the regulation of inflammatory responses.

        Are there any clinical interventions targeting GSK3A for diabetes management? 04/02/2016

        Researchers are investigating the potential of GSK3A inhibitors to improve insulin sensitivity and glucose homeostasis in diabetes.

        Ask a Question for All GSK3A Products

        Required fields are marked with *

        My Review for All GSK3A Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /
        • Service lnquiry:

        Stay Updated on the Latest Bioscience Trends