Active Recombinant Full Length Human GSK3A Protein, GST-tagged
Cat.No. : | GSK3A-9932HF |
Product Overview : | Full-length human GSK3α [1-483(end) amino acids of accession number NP_063937.2] was expressed as N-terminal GST-fusion protein (78 kDa) using baculovirus expression system. GST-GSK3α was purified by using glutathione sepharose chromatography. |
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Source : | Insect (sf21) |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5 |
Bio-activity : | The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000. |
Protein length : | 1-483 |
Purity : | 56% |
Applications : | SDS-PAGE |
Storage : | Store at -80C. Avoid repeating freeze-thaws. |
Gene Name : | glycogen synthase kinase 3 alpha |
Official Symbol : | GSK3A |
Synonyms : | GSK3A |
Protein Refseq : | NP_063937.2 |
UniProt ID : | P49840 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewIts high purity and integrity ensure reliable and reproducible results, minimizing any potential variability in my experimental outcomes.
This aspect is crucial in maintaining the scientific rigor of my studies and strengthens the validity of my research findings.
the manufacturer's commitment to continuous improvement and innovation is evident in their constant efforts to enhance the GSK3A protein.
Q&As (5)
Ask a questionGSK3A is implicated in insulin signaling and glucose metabolism, and its dysregulation is associated with insulin resistance, a key feature of type 2 diabetes.
Yes, GSK3A is implicated in pathways associated with mood regulation, and inhibitors are being investigated for their potential in treating mood disorders.
Yes, there is ongoing research to develop GSK3A modulators as potential anti-inflammatory agents.
GSK3A is involved in inflammatory signaling pathways, and its activity is linked to the regulation of inflammatory responses.
Researchers are investigating the potential of GSK3A inhibitors to improve insulin sensitivity and glucose homeostasis in diabetes.
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