Recombinant Human GSK3A protein, His & GST-tagged
Cat.No. : | GSK3A-634H |
Product Overview : | Recombinant Human GSK3A aa. (Gln115~Leu409 (Accession # P49840)) fused with N-terminal His & GST tag was produced in E. coli cells. |
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Description : | This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. |
Source : | E. coli |
Species : | Human |
Tag : | His&GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 65.8kDa |
Protein length : | Gln115~Leu409 (Accession # P49840) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 7.3. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | GSK3A glycogen synthase kinase 3 alpha [ Homo sapiens (human) ] |
Official Symbol : | GSK3A |
Synonyms : | GSK3A; glycogen synthase kinase 3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A |
Gene ID : | 2931 |
mRNA Refseq : | NM_019884.2 |
Protein Refseq : | NP_063937.2 |
UniProt ID : | P49840 |
Products Types
◆ Recombinant Protein | ||
GSK3A-0315H | Recombinant Human GSK3A Protein (S2-S483), Tag Free | +Inquiry |
GSK3A-3962M | Recombinant Mouse GSK3A Protein, His (Fc)-Avi-tagged | +Inquiry |
GSK3A-055H | Recombinant Human GSK3A Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Gsk3a-3317M | Recombinant Mouse Gsk3a Protein, Myc/DDK-tagged | +Inquiry |
GSK3A-0316H | Recombinant Human GSK3A Protein (S2-S483), GST tagged | +Inquiry |
◆ Lysates | ||
GSK3A-5723HCL | Recombinant Human GSK3A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewIts high purity and integrity ensure reliable and reproducible results, minimizing any potential variability in my experimental outcomes.
This aspect is crucial in maintaining the scientific rigor of my studies and strengthens the validity of my research findings.
the manufacturer's commitment to continuous improvement and innovation is evident in their constant efforts to enhance the GSK3A protein.
Q&As (5)
Ask a questionGSK3A is implicated in insulin signaling and glucose metabolism, and its dysregulation is associated with insulin resistance, a key feature of type 2 diabetes.
Yes, GSK3A is implicated in pathways associated with mood regulation, and inhibitors are being investigated for their potential in treating mood disorders.
Yes, there is ongoing research to develop GSK3A modulators as potential anti-inflammatory agents.
GSK3A is involved in inflammatory signaling pathways, and its activity is linked to the regulation of inflammatory responses.
Researchers are investigating the potential of GSK3A inhibitors to improve insulin sensitivity and glucose homeostasis in diabetes.
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