| MAPK signaling pathway |
CACNG1; IL1R2; CACNA1H; TAOK1; RAC3A; PPM1AA; MAP2K2; CACNA2D3; FGFR1A; LRRK2 |
| ErbB signaling pathway |
MAP2K2; CAMK2G1; MAPK3; PIK3R1; HRASA; CAMK2B; HBEGFA; PAK4; PRKCBB; MAPK10 |
| Ras signaling pathway |
PLA2G4D; AKT1; Fasl; GRIN2A; GNB4; RASA3; GNG10; RAC2; RASAL3; CALM3 |
| Rap signaling pathway |
PDGFRB; MAPK12; CDC42; FYB; MAP2K2; MLLT4; FGF19; LCP2; NGFR; ANGPT1 |
| cGMP-PKG signaling pathway |
LOC100328615; INS2; INS1; GNA12; INSR; GNAI3; VASP; PPP1R12A; GTF2IRD1; CALM3 |
| cAMP signaling pathway |
CALM2; RAC1; ATP1B3; CAMK4; HTR1B; AKT2; PDE3B; ATP1A3; PPP1CA; RAC3 |
| Chemokine signaling pathway |
CXCL10; ITK; CCR8; GNB3; IL-8; PF4; PARD3; GNG7; CXCR6; CCR1 |
| HIF- signaling pathway |
MKNK2; NOS2; IFNG; PFKFB3; VEGFA; GAPDH; FLT1; HMOX1; PDHA2; MAP2K1 |
| FoxO signaling pathway |
NLK2; CCND2; AKT3A; PDPK1B; MAPK13; GRB2A; FASLG; HRASA; GABARAPL2; GRB2B |
| Sphingolipid signaling pathway |
ACER1; GNAI3; MAPK10; PRKCZ; OPRD1; GNAI2; DEGS2; PIK3CB; SMPD1; PPP2CA |
| Phospholipase D signaling pathway |
INS; PIK3CD; GRM8; SYK; MRAS; PIK3CB; FCER1A; PRKCA; RRAS; MAP2K1 |
| Oocyte meiosis |
YWHAG; PPP3CCB; YWHAE1; PPP1CAB; PTTG1; RPS6KA3; PPP1CB; PRKACBB; CALM3A; SMC1AL |
| mTOR signaling pathway |
STRADA; DDIT4; INS; RPS6KA3; PIK3CG; RPTOR; MLST8; TNF; RPS6KB1B; PIK3R3A |
| PIK-Akt signaling pathway |
FGF6; CCNE1; LAMC1; ITGB6; PPP2R5B; FGF14; LAMB3; IL4R; PIK3CD; CCNE2 |
| Adrenergic signaling in cardiomyocytes |
CACNG4; SLC14A2; ADCY7; CACNA1DA; CACNG6A; ACTC1; PPP1CAB; TNNI3; ATF6B; TPMA |
| Vascular smooth muscle contraction |
PRKACAA; PRKCH; PRKCBA; MYL6B; AGTR1B; PPP1R12A; ADRA1BB; PLCB4; CALM2A; EDNRAA |
| Dorso-ventral axis formation |
MAP2K1; PPP1R2P9; ETS1; NOTCH2; GRB2; KRAS; CPEB1B; GRB2A; ETS2; PIWIL1 |
| TGF-beta signaling pathway |
PITX2; LFT2; IFNG1-2; BAMBIB; TGFB1A; ROCK2B; BMP7B; CUL1A; ID2A; INHBA |
| Axon guidance |
EFNA4; EPHA3; DUSP1; NFATC2; ARHGEF12; COL6A2; DUSP5; ARPC5; KCNQ3; DPYSL2 |
| VEGF signaling pathway |
PRKCG; KRAS; PRKCB; PTK2; PIK3R1; CDC42L2; VEGFA; RAC1; MAPKAPK2A; PXNA |
| Osteoclast differentiation |
NFKBIA; FCGR2A; PIK3R5; TNF; RAC1; SIRPG; LILRB4; STAT1; IFNGR1; AKT2 |
| Focal adhesion |
LAMB2; VEGFB; MYL5; RAP1B; PIK3R3A; ITGA10; BRAF; ITGA3; RHOA; CCND1 |
| Adherens junction |
CSNK2A2; SMAD3A; EGFRA; INSRB; BAIAP2A; NLK1; CDC42L2; WASB; ACTN3A; CTNNA3 |
| Gap junction |
GRM5; GJD2; PDGFRB; ADRB3B; PRKACA; DRD1A; PRKCBB; TUBA1B; GNAIA; CX43 |
| Signaling pathways regulating pluripotency of stem cells |
IL6ST; PIK3R3; HOXB1; KRAS; FZD8; SOX2; WNT1; AXIN1; MAPK1; MAP2K2 |
| Platelet activation |
ROCK1; PTGS1; P2RY12; RAP1A; SNAP23; ACTG1; ITGA2; PRKACB; MYLK; PTGIR |
| Toll-like receptor signaling pathway |
IFNB; AKT2L; PIK3R2; SPP1; TAB2; TRAF6; MAPK10; TLR1LA; CD86; MAP2K7 |
| NOD-like receptor signaling pathway |
HSP90AA1.2; IL1B; MAPK1; NFKBIA; PSTPIP1; TNF; LOC100033925; CXCL2; IL8L1; NLRP1 |
| Natural killer cell mediated cytotoxicity |
PRKCA; CD247; ULBP3; PPP3CB; KIR2DS4; FCGR4; PIK3CD; KIR2DS3; MAP2K1; ICAM2 |
| T cell receptor signaling pathway |
GRAP2; GSK3B; PIK3CG; PTPN6; PLCG1; MAPK3; TNF; RHOA; PPP3CA; MAPK1 |
| B cell receptor signaling pathway |
NFATC3; GSK3AB; cgr2b; INPP5D; PTPN6; CDK7; NRAS; PIK3CA; RASGRP3; NFKBIA |
| Fc epsilon RI signaling pathway |
PIK3R1; MAPK13; IL3; PIK3CD; GM-CSF; VAV3; FYN; INPP5D; VAV2; AKT2 |
| Fc gamma R-mediated phagocytosis |
WASF2; FCGR2A; BIN1; LIMK1; PIP5K1A; CFL1; VAV2; SPHK2; PIK3CA; RPS6KB1 |
| TNF signaling pathway |
MAP2K1; CXCL3; MAP2K7; LTA; RPS6KA5; TRAF3; IKBKG; TRAF5; TNFAIP3; MMP3 |
| Circadian entrainment |
GNGT1; GRIA2; GRIA1; GNB3; GUCY1B3; CAMK2G; GNG3; GNG4; PLCB2; GNB1 |
| Long-term potentiation |
RAF1; ITPR3; CAMK2G; RPS6KA1; PRKCA; RPS6KA6; PPP3R2; PLCB4; CAMK2A; EP300 |
| Neurotrophin signaling pathway |
MAP2K2; CALM1; RAPGEF1; MAGED1; NTRK1; RPS6KA2; IKBKB; NTRK2; MAPK3; PIK3CD |
| Retrograde endocannabinoid signaling |
GABRG3; RIMS1; GNAO1; MAPK8; GABRA6; GNGT1; GABRP; ITPR1; GRIA3; GNG8 |
| Glutamatergic synapse |
ITPR1; PLA2G4F; SLC17A8; Adcy4; GRIN3B; GNB1; PLA2G4C; GLS2; PPP3R2; GNG4 |
| Cholinergic synapse |
CHRM4; HRAS; GNAI3; GNB1; GNG8; KCNQ1; CHRM5; ITPR3; PRKACA; KCNJ12 |
| Serotonergic synapse |
GNG13; GNGT1; GNAI2; HTR1A; Casp3; HTR3E; GABRB2; HTR7; GNAQ; MAPK3 |
| Long-term depression |
RYR1; PRKG1; GRID2; GNA13; IGF1; IGF1R; GNAZ; CRHR1; ARAF; GNAI3 |
| Regulation of actin cytoskeleton |
GNA12; WASLA; ITGA10; PIP4K2B; MRAS; BAIAP2A; PIK3CB; RAC1; ACTN3; MLCK2 |
| Insulin signaling pathway |
AKT2; MAP2K2B; PTPRFB; GRB2; PPP1CBL; MAPK1; NRAS; LIPE; HRASB; PPP1R3C |
| GnRH signaling pathway |
MAPK13; CACNA1DA; MAP2K2B; CACNA1SA; CAMK2D2; MAP3K2; MAPK3; GNAQ; MAP2K2; ADCY1A |
| Progesterone-mediated oocyte maturation |
PRKACA; CPEB1; MAPK9; MAPK14B; RPS6KA6; PIK3R3; ANAPC5; ANAPC2; MAPK14A; MAPK13 |
| Estrogen signaling pathway |
ATF6B; GNAI3; SP1; PLCB2; PIK3R1; HSPA6; GNAI1; KCNJ6; MAPK1; GNAS |
| Melanogenesis |
WNT11B; CALM1A; ADCY1A; PRKCA; PLCB1; WNT7B; WNT6; POMC; GNAQ; WNT11 |
| Prolactin signaling pathway |
MAPK11; MAPK1; NEK3; PIK3CD; SHC2; PIK3CB; MAPK12; FOS; PRL; MAP2K2 |
| Thyroid hormone signaling pathway |
PRKCG; MED30; RXRA; KAT2A; STAT1; PLCD4; RCAN1; ACTG1; HDAC3; SIN3A |
| Oxytocin signaling pathway |
CACNG7; PIK3CB; NRAS; CACNA2D2; MYL6B; MYLK3; NPR1; PPP3R1; CAMK2B; CACNB2 |
| Type II diabetes mellitus |
SOCS3; PRKCE; IRS1; IRS4; INS-IGF2; PIK3R5; MTOR; INS2; PIK3CD; MAFA |
| Aldosterone-regulated sodium reabsorption |
KRAS; MAPK3; PIK3CB; PIK3CG; IGF1; ATP1A4; ATP1B3; HSD11B2; PIK3R3; PRKCG |
| Alzheimers disease |
MT-ATP6; NDUFA5; ATP5B; GRIN2C; ITPR1; NDUFA6; SDHB; ATP5F1; PPP3CC; NDUFA10 |
| Prion diseases |
FYN; LAMC1; CCL5; STIP1; C6; IL1A; C9; C8A; C1QC; PRKACG |
| Alcoholism |
CAMKK1; NPY; GRB2; SLC18A2; HDAC8; HIST2H2AA4; PPP1CA; DRD1A; GM14478; HIST1H2BK |
| Shigellosis |
IKBKB; PFN1; SRC; U2AF1L4; CTTN; RELA; FBXW11; ROCK1; MAD2L2; ELMO2 |
| Salmonella infection |
MAPK10; TLR4; RHOG; CXCL8B.3; MAPK8B; KLC4; MYH9; CXCL2; NLRC4; CCL4 |
| Pertussis |
MYD88; MAPK3; CALM1; GNAI3; CASP7; CALM2; ITGB1; CALML5; CFL2; C4BPB |
| Leishmaniasis |
NFKB1; IFNG; FCGR3A; ITGB2; TNF; C3; TGFB2; NCF2; HLA-DPA1; HLA-DMA |
| Chagas disease (American trypanosomiasis) |
PIK3R5; CCL3; RELA; CALR; GNA14; CD3E; CD3D; PPP2R2A; TGFB1; GNA15; TGFBR2 |
| Toxoplasmosis |
LAMB2; BIRC2; HLA-DQB1; IRAK1; TRAF6; H2-AB1; Toxoplasma Gondii Major Surface Antigen P30; BIRC7; HLA-DRB4; IRGM |
| Tuberculosis |
CALM4; FCGR3B; IRAK2; NFKB1; MAPK11; HLA-DRB4; RAB5B; IL1A; CAMK2D; PLK3 |
| Hepatitis C |
EIF2AK1; Ifna11; IFNAR2; CLDN23; TRAF6; CLDN16; PIK3CG; IFNA8; DDX58; IFN-a |
| Hepatitis B |
TICAM2; IFNA13; FAS; IFNA12; PIK3CB; NFKBIA; TRP53; TGFBR1; CASP9; IFNA1 |
| Influenza A |
PIK3R5; DNAJB1; RNASEL; TLR7; FURIN; IFNAR1; OAS1; ADAR; BMA1; NXF2 |
| Pathways in cancer |
PPARG; FOXO1; PIK3R2; GNGT1; PTCH2; FASLG; STAT3; PIAS2; EP300; MTOR |
| Viral carcinogenesis |
YWHAH; GTF2B; RELA; TRAF5; PKM; TRAF3; HIST1H4E; CDK1; HIST1H2BA; HIST1H2BJ |
| Proteoglycans in cancer |
PLAU; FZD9; TWIST2; PLCE1; MAPK3; FAS; WNT11; MTOR; EZR; GRB2 |
| MicroRNAs in cancer |
RDX; BMF; PLAU; RPS6KA5; RPTOR; EZH2; SHC1; HDAC4; MAPK7; HDAC1 |
| Colorectal cancer |
SMAD2; AXIN1; MAP2K1; MSH6; MLH1; AKT2; TCF7L2; GSK3B; TGFB2; RAF1 |
| Renal cell carcinoma |
FLCN; PAK1; TCEB2; TGFA; RAP1A; PDGFB; PIK3CG; MAP2K1; ARNT2; ARNT |
| Pancreatic cancer |
TGFB2; TGFBR1; BAD; NFKB1; SMAD2; PLD1; TRP53; PIK3R3; BRAF; TGFB3 |
| Endometrial cancer |
ERBB2; FOXO3; ARAF; AXIN2; CTNNA2; PIK3R3; CTNNA3; PIK3R5; ILK; MAP2K2 |
| Glioma |
CALM1; SHC4; ARAF; CCND1; RAF1; PRKCG; PIK3CD; PIK3R2; MAP2K2; NRAS |
| Prostate cancer |
SPRY1; SRD5A2; MAPK1; ARID1A; FGFR1; FOXA1; NFKBIA; AKT2; SOS1; TGFA |
| Thyroid cancer |
TRP53; PPARG; HRAS; PAX8; KRAS; RXRA; MAPK1; TP53; TFG; RXRG |
| Melanoma |
HRAS; FGF1; PIK3R1; PIK3CD; RAF1; ARAF; FGF19; TRP53; FGF14; IGF1R |
| Bladder cancer |
VEGFA; MMP9; KRAS; HBEGF; DAPK3; CCND1; CDH1; ERBB2; TYMP; CXCL8 |
| Chronic myeloid leukemia |
STAT5A; TRP53; TGFB3; BAD; MAPK1; HRAS; NFKB1; SOS1; AKT2; BCL2L1 |
| Acute myeloid leukemia |
KIT; STAT5B; TCF7; MAP2K2; SPI1; MAP2K1; CCND1; PIK3R2; RARA; GRB2 |
| Non-small cell lung cancer |
MAPK1; MAP2K2; TP53; PIK3R1; AKT2; MAPK3; PDPK1; AKT1; PRKCG; PRKCA |
| Central carbon metabolism in cancer |
SIRT3; PDHA2; PIK3R1; PTEN; NTRK1; PIK3CG; MAP2K1; PKM; PDHA1; PFKP |
| Choline metabolism in cancer |
AKT1; PDPK1; EGF; TSC1; TAE1; RPS6KB1; PIP5K1B; PDGFB; CHKB; PCYT1A |
