MAPK1-918H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant Human MAPK1 protein (Met 1-Ser 360), fused with the GST tag at the N-terminus, was expressed inInsect cells.
Description :
Mitogen-activated protein kinase 1, also known as Extracellular signal-regulated kinase 2, ERK-2, and MAPK1, is a member of the protein kinase superfamily and MAP kinase subfamily. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. MKP-3 is a dual specificity phosphatase exclusively specific to MAPK1 for its substrate recognition and dephosphorylating activity. The activation of MAPK1 requires its phosphorylation by upstream kinases.
Source :
Insect cells.
Molecular Mass :
The recombinant human ERK2/GST chimera consists of 585 amino acids and predicts a molecular mass of 67 kDa as estimated in SDS-PAGE under reducing conditions.
Predicted N Terminal :
Met.
Purity :
> 98 % as determined by SDS-PAGE.
Formulation :
Lyophilized from sterile 50mM Tris , 100 mM Nacl, 0.5mM PMSF, 10%Glycerol, pH 8.0.
Endotoxin :
< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution :
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Storage And Stability :
Samples are stable for up to twelve months from date of receipt at -700C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.