MAPK9

  • Official Full Name

    MAPK9 mitogen-activated protein kinase 9

  • Background

    Stress-activated Protein Kinases (SAPKs) are strongly activated in response to adverse stimuli such as heat and osmotic shock, UV light and other DNA-damaging reagents, and inhibitors of protein synthesis. They are also activated strongly in response to agonists that are released or produced under conditions of stress, such as proinflammatory cytokines. The SAPK1/jnk family consists of 3 isoforms:SAPK1 alpha/jnk2; SAPK1 beta/jnk3; SAPK1 beta/jnk1.
  • Synonyms

    MAPK9; mitogen-activated protein kinase 9; PRKM9; JNK2; Jun kinase; p54a; SAPK; MAPK 9; MAP kinase 9; c-Jun kinase 2; c-Jun N-terminal kinase 2; stress-activated protein kinase 1a; stress-activated protein kinase JNK2; JNK2A; JNK2B; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Antibody
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Rabbit
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • His|MBP
    • SUMO
    • Myc
    • DDK
    • N/A
    • N
    • No tag
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken MAPK9-6652C Recombinant Chicken MAPK9 Mammalian Cell His
    Human MAPK9-4485HCL Recombinant Human MAPK9 293 Cell Lysate HEK293 N/A
    Human CAB11582RH Rabbit Monoclonal Antibody to Human Mitogen-activated Protein Kinase 9 Rabbit N/A
    Human MAPK9-1349H Recombinant Human Mitogen-Activated Protein Kinase 9, His-tagged E.coli His
    Human MAPK9-5488H Recombinant Human Mitogen-Activated Protein Kinase 9 E.coli His
    Human MAPK9-4486HCL Recombinant Human MAPK9 293 Cell Lysate HEK293 N/A
    Human MAPK9-29670TH Recombinant Human MAPK9 Insect Cell N/A
    Human MAPK9-1266H Recombinant Human Mitogen-Activated Protein Kinase 9, His-tagged Insect Cell His
    Human MAPK9-45H Recombinant Human Mitogen-activated Protein Kinase 9 E.coli N/A
    Human MAPK9-4487HCL Recombinant Human MAPK9 293 Cell Lysate HEK293 N/A
    Human MAPK9-44H Recombinant Human Mitogen-activated Protein Kinase 9, His-tagged E.coli His
    Human MAPK9-238H Recombinant Human MAPK9 protein, His-tagged E.coli His
    Human MAPK9-1265H Recombinant Human Mitogen-Activated Protein Kinase 9 E.coli N/A
    Human MAPK9-2421H Recombinant Human MAPK9 Protein, His-tagged E.coli N-His
    Human MAPK9-1581H Recombinant Human MAPK9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MAPK9-1267H Recombinant Human Mitogen-Activated Protein Kinase 9 E.coli N/A
    Human MAPK9-2746H Recombinant Human MAPK9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MAPK9-1052H Recombinant Human Mitogen-Activated Protein Kinase 9, GST-Tagged Sf9 Insect Cell GST
    Human MAPK9-3206H Recombinant Human MAPK9 protein, His-SUMO-tagged E.coli His-SUMO
    Human MAPK9-155H Recombinant Human MAPK9 protein, His/MBP-tagged E.coli His/MBP
    Human MAPK9-1138H Recombinant Human MAPK9 Protein (M1-E364), Tag Free E.coli No tag
    Human MAPK9-1139H Recombinant Human MAPK9 Protein (M1-E364), His tagged E.coli His
    Mouse Mapk9-3948M Recombinant Mouse Mapk9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat Mapk9-1053R Recombinant Rat Mitogen-Activated Protein Kinase 9, GST-Tagged E.coli GST
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • MAPK9 Related Signal Pathway

    MAPK9 involved in several pathways and played different roles in them. We selected most pathways MAPK9 participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathwayMAPK12;CACNA1H;FGF2;FGF11;RAC1B;Fgf15;NTRK2;MAX;MAP2K2A
    ErbB signaling pathwayRPS6KB2;SOS1;ERBB3B;ABL1;PAK2B;PAK1;AREGB;CAMK2A;PIK3R5
    Ras signaling pathwayPdgfa&Pdgfb;FOXO4;PIK3CG;GAB2;PAK6;FGF3;GRB2;RELA;REL
    cAMP signaling pathwayBDNF;LIPE;CREB3L3;MAPK9;GABBR1;ACOX1;PDE4C;PIK3CA;ARAP3
    FoxO signaling pathwayFOXG1A;AKT2L;RAG2;MAPK14A;GRM1;PIK3R3;TNFSF10;TGFB1A;CDKN1BB
    Sphingolipid signaling pathwayTNF;PLD1;CERS5;PRKCB;GAB2;RELA;S1PR5;KRAS;ACER1
    Protein processing in endoplasmic reticulumHSP90B1;DNAJC5G;UBQLN4;CAPN2B;TUSC3;MAP2K7;DNAJB1B;BAK1;SAR1B
    Wnt signaling pathwaySFRP1A;DAAM2;NKD2B;PORCNL;DVL3A;WNT9B;PRKACBB;RAC3B;RAC2
    Osteoclast differentiationLILRA2;PIK3R5;FCGR3B;STAT1;LILRB2;IL1A;TGFBR2;FYN;GAB2
    Focal adhesionPTK2AA;COL24A1;LAMB3;LAMB4;PRKCA;CAPN2A;CAPN2;PTEN;PDGFA
    Toll-like receptor signaling pathwayIFNA12;MAP2K2B;IFNA6;IL-8;PIK3R3B;CCL3L3;IFNA14;IFNA10;TLR4BB
    NOD-like receptor signaling pathwayMAPK14A;IL6;RELA;TNF;NLRP1;IL18;NFKBIAA;IL8L2;CASPA
    RIG-I-like receptor signaling pathwayMAPK14A;Ifna15;MAPK9;TMEM173;MAPK14B;MAPK10;TNF;TRADD;IFNA4
    T cell receptor signaling pathwayCDC42;CD3G;MAP2K7;TNF;GRAPA;PPP3CB;PAK7;MAPK13;MAP3K7
    Fc epsilon RI signaling pathwayMAP2K2;LCP2;PLA2G4B;MAPK1;AKT1;GAB2;MAPK11;PIK3R3;INPP5D
    TNF signaling pathwayMAPK3;TRADD;NFKBIA;PIK3R1;MAPK10;MAPK13;IL6;MMP9;ATF4
    Neurotrophin signaling pathwayMAPK3;NGFRAP1;ARHGDIB;MAPK7;SHC4;MAPK9;PIK3CD;MAPK12;SH2B1
    Retrograde endocannabinoid signalingMAPK8;PRKCB;GABRG3;SLC17A7;Adcy4;GABRA5;GABRA4;GNG13;PTGS2
    Dopaminergic synapseITPR3;PPP2R1B;PPP2R3C;PPP2R2D;ITPR1;GNG3;GSK3A;PRKACG;COMT
    Inflammatory mediator regulation of TRP channelsPRKACG;TRPV4;ASIC1;CYP2C55;PLA2G4D;PIK3CG;PLCB4;CYP2C38;ALOX12E
    Insulin signaling pathwayPKLR;TRIP10A;INSRA;PPP1R3CA;PYGMA;SOCS3;ACACA;PIK3CA;PPP1CAB
    GnRH signaling pathwayCALM3A;PRKACG;MAP2K1;CACNA1DA;MAP2K2;MAPK8B;NRAS;RAF1;MAPK9
    Progesterone-mediated oocyte maturationHSP90AA1;CDC23;AKT1;MAD1L1;RAF1;SPDYA;PRKACBB;RPS6KA6;PIK3R2
    Prolactin signaling pathwaySOCS3;FOS;GRB2;INS1;MAP2K1;IRF1;SHC2;PPIB;SIRPA
    Adipocytokine signaling pathwayAKT2L;PCK1;RXRB;RXRGA;IRS4;RXRG;G6PCA.1;G6PC2;PTPN11B
    Type II diabetes mellitusADIPOQ;MAPK1;PIK3CD;SOCS2;SLC2A2;IRS2;PIK3R1;INSR;HKDC1
    Insulin resistanceSLC27A1B;MLXIPL;CRTC2;PRKCBB;CD36;PIK3CG;PPP1R3CB;MAPK9;RELA
    Non-alcoholic fatty liver disease (NAFLD)NDUFA1;INS1;NDUFC1;NDUFB5;LEP;PPARA;SREBF1;NDUFS5;GSK3B
    Epithelial cell signaling in Helicobacter pylori infectionCDC42;NFKBIA;RELA;F11R;PTPN11;SRC;IKBKG;ATP6V1C2;PLCG1
    ShigellosisMAPK8;U2AF1L4;PFN4;MAPK13;IKBKG;NFKBIB;ITGB1;RAC1;RELA
    Salmonella infectionNOS2;ACTB1;IL-8;DYNC1I1;MYD88;MAPK12;MAPK9;TLR5B;WASB
    PertussisIL1A;CASP7;NFKB1;C1QA;MAPK10;C4BPA;TRAF6;C4A;CALM2
    Chagas disease (American trypanosomiasis)IL1B2;NFKB1;PLCB3;GNA15;MAPK10;Il2;PLCB1;PIK3CD;IL-8
    ToxoplasmosisBIRC8;PIK3CB;PIK3CD;IKBKG;HSPA2;IFNGR2;CD40;MAPK12;GNAO1
    TuberculosisFADD;AKT2;FCGR3B;C3;CEBPG;ATP6V0C;TGFB2;IFNA7;CALM2
    Hepatitis CIFN-a;TLR3;IFNA16;NR1H3;TRADD;OCLN;CLDN15;PIK3R3;NFKBIA
    Hepatitis BELK1;TP53;IFNAR1;PRKCB;DDX3X;IKBKB;Fasl;TNF;RAF1
    Influenza AIL12B;TNFRSF1A;MAP2K1;HLA-DQA2;IL18;BLA;ACTB;NXF3;IFNGR2
    Herpes simplex infectionEIF2S1B;MAPK8B;PTPN11A;SRPK1A;HNRPKL;MHC2DEB;JAK2A;SRSF3;TAF3
    Epstein-Barr virus infectionHLA-DRB5;PIK3CD;STAT3;PIK3R1;MAPK8;SFPI1;IL10RB;HLA-F;POLR3GL
    Pathways in cancerFGF8;EGLN3;CXCL12;RUNX1;MLH1;FH;FZD1;FGF5;RALB
    Colorectal cancerPIK3R1;TGFBR1;BAD;ARAF;SMAD4;RHOA;DCC;MSH2;PIK3CA
    Pancreatic cancerSMAD3;VEGFA;CDC42;BRAF;TP53;SMAD4;BCL2L1;TGFB3;MAP2K1
    Choline metabolism in cancerSLC22A3;MAP2K2;MAPK10;PRKCG;PPAP2B;SLC44A1;FOS;SLC44A2;WASF3

    MAPK9 has several biochemical functions, for example, ATP binding, JUN kinase activity, cysteine-type endopeptidase activator activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK9 itself. We selected most functions MAPK9 had, and list some proteins which have the same functions with MAPK9. You can find most of the proteins on our site.

    Function Related Protein
    ATP bindingNLRP4C;CAMK2A;HELZ2;MOV10;CDK13;MAPK8B;HSPA8;RAF1B;SMC1AL
    JUN kinase activityMAPK9;MAPK8;ALPK2;MAPK10
    cysteine-type endopeptidase activator activity involved in apoptotic processBAD;NLRP1;CARD8;PYCARD;BCL2L13;MAPK9;CASP1;CTSC;CTSH
    mitogen-activated protein kinase kinase kinase bindingMARVELD3;MAPK9;MAP3K11;MAP4K2;CDC37;TRAF2;MAPK1;MAPK8IP3;MAP2K1
    protein bindingTTC23L;PSMD3;KIF22;CNTNAP4;BANF1;MAL2;FBXW7;TMEM171;UBE2G2
    transcription factor bindingNKX2-1;RNF4;WWP2;APBB2;PARP1;CD34;AHR;IGHMBP2;TFDP1B

    MAPK9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK9 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK9.

    ARRB2; ARRB1; WDR62; SF3B4; CEP44

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