Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

PSENEN

  • Official Full Name

    presenilin enhancer gamma secretase subunit

  • Overview

    Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimers disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Synonyms

    PSENEN; presenilin enhancer gamma secretase subunit; PEN2; PEN-2; MDS033; MSTP064; gamma-secretase subunit PEN-2; presenilin enhancer 2 homolog; hematopoietic stem/progenitor cells protein MDS033;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Dictyostelium discoideum (Slime mold)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In vitro E. coli expression system
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PSENEN-2005H Recombinant Human PSENEN, GST-tagged E.coli GST 1-101aa
Human PSENEN-2789HCL Recombinant Human PSENEN 293 Cell Lysate HEK293 N/A
Human PSENEN-2467H Recombinant Human PSENEN Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-101aa
Mouse PSENEN-13547M Recombinant Mouse PSENEN Protein Mammalian Cell His
Mouse Psenen-5172M Recombinant Mouse Psenen Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PSENEN-7202M-B Recombinant Mouse PSENEN Protein Pre-coupled Magnetic Beads HEK293
Mouse PSENEN-7202M Recombinant Mouse PSENEN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PSENEN-4760R Recombinant Rat PSENEN Protein Mammalian Cell His
Rat PSENEN-4419R Recombinant Rat PSENEN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PSENEN-4419R-B Recombinant Rat PSENEN Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL6288BF Recombinant Full Length Bovine Gamma-Secretase Subunit Pen-2(Psenen) Protein, His-Tagged E.coli expression system His Full Length (1-101)
Dictyostelium discoideum (Slime mold) RFL10580DF Recombinant Full Length Dictyostelium Discoideum Probable Gamma-Secretase Subunit Pen-2(Psenen) Protein, His-Tagged E.coli expression system His Full Length (1-97)
Mus musculus (Mouse) RFL22065MF Recombinant Full Length Mouse Gamma-Secretase Subunit Pen-2(Psenen) Protein, His-Tagged E.coli expression system His Full Length (1-101)
Rattus norvegicus (Rat) RFL17837RF Recombinant Full Length Rat Gamma-Secretase Subunit Pen-2(Psenen) Protein, His-Tagged E.coli expression system His Full Length (1-101)
Rhesus Macaque PSENEN-3645R Recombinant Rhesus monkey PSENEN Protein, His-tagged Mammalian Cell His
Rhesus Macaque PSENEN-3463R Recombinant Rhesus Macaque PSENEN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PSENEN-3463R-B Recombinant Rhesus Macaque PSENEN Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PSENEN-11617Z Recombinant Zebrafish PSENEN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PSENEN Related Research Area

PSENEN involved in several pathways and played different roles in them. We selected most pathways PSENEN participated on our site, such as Notch signaling pathway, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSENEN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Notch signaling pathwayNOTCH3;MFNG;CTBP1;KAT2B;RBPJL;DLC;DTX2;CTBP2A;DVL3A
Alzheimers diseaseSNCA;NDUFB4;TNF;MAPK3;NDUFB11;COX8A;NDUFB8;UQCRC1;Casp3

PSENEN has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSENEN itself. We selected most functions PSENEN had, and list some proteins which have the same functions with PSENEN. You can find most of the proteins on our site.

Function Related Protein
protein bindingGTF3C4;IWS1;CNO;PPP1R1A;PSMA4;KISS1R;HLCS;MKI67;RPH3A

PSENEN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSENEN here. Most of them are supplied by our site. Hope this information will be useful for your research of PSENEN.

NCSTN; FTL; TMED10; CREB3; THBD; APH1A

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All PSENEN Products

Required fields are marked with *

My Review for All PSENEN Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends