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ABCC9

Official Full Name

ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Overview

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants.
Synonyms

ABCC9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; SUR2; ABC37; CANTU; CMD1O; ATFB12;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.Coli or Yeast
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ABCC9-3732H	Recombinant Human ABCC9, His-tagged	E.Coli or Yeast	His	1549	Inquiry
Mouse	Abcc9-3734M	Recombinant Mouse Abcc9, His-tagged	E.Coli or Yeast	His	1533	Inquiry
Rat	ABCC9-409R	Recombinant Rat ABCC9 Protein	Mammalian Cell	His		Inquiry
Rat	ABCC9-64R	Recombinant Rat ABCC9 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	ABCC9-64R-B	Recombinant Rat ABCC9 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	ABCC9-3267Z	Recombinant Zebrafish ABCC9	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

ABCC9 involved in several pathways and played different roles in them. We selected most pathways ABCC9 participated on our site, such as ABC transporters, ABC-family proteins mediated transport, ATP sensitive Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCC9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
ABC transporters	ABCC8;CFTR;ABCB1A;ABCC4;ABCB9;ABCD3A;ABCB8;ABCB5;SUR2A
ABC-family proteins mediated transport	ABCE1;ABCB8;ABCA4A;EIF2S1;ABCC9;ABCC2;KCNJ11;ABCG4B;ABCD3B
ATP sensitive Potassium channels	KCNJ11;ABCC9;KCNJ8
Inwardly rectifying K+ channels	KCNJ8;KCNJ1A.3;KCNJ10;KCNJ1A.4;KCNJ14;KCNJ15;KCNJ1A.5;KCNJ11;ABCC9
Neuronal System	KCNMB2;DDX1;BCHE;SLC6A1A;KCNK1B;KCNJ8;KCNC2;KCNJ1A.1;PPFIA2
Potassium Channels	KCNH5A;KCNA10;KCNA1;KCNH1B;KCNH2;KCNB1;KCNC4;KCNAB2;KCNF1
Transmembrane transport of small molecules	ANO6;MAGT1;SLC38A5B;SLC9A8;SLC43A2;SLC6A20B;RHBG;SLC6A6A;SLC4A4A

ABCC9 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCC9 itself. We selected most functions ABCC9 had, and list some proteins which have the same functions with ABCC9. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	ACTC1;ABCB1;ATP1A1A.3;HK1;TAE1;KCNJ10;RFC4;CDK6;KIF22
ATPase activity, coupled to transmembrane movement of substances	ABCA1;ABCC9;ABCG3;ABCA7;ATP6V1D;ABCG5;ABCD1;ABCC1;ABCA1B
ion channel binding	PANX1;SCN5A;ACTN2;RNF207;SCN3B;KCNH1;SRI;RANGRF;KCND3
potassium channel activity	KCNG4A;KCNK1B;KCNH5;AQP1;KCNK9;TRPM5;KCNK1A;KCNC3B;KCNQ2
potassium channel regulator activity	KCNAB2;KCNMB1;KCNS3;NEDD4L;KCNIP1;KCNMB2;ARPP19;KCNV1;KCNMB4
sulfonylurea receptor activity	ABCC8;ABCC9
transporter activity	ABCA1B;SLC25A31;RBP5;SV2C;SLC5A3A;PTGDSB;STEAP1;FABP7A;VPS9D1

ABCC9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCC9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCC9.

KCNJ11