actb1

ACTB1 is predicted to function as a structural constituent of the postsynaptic actin cytoskeleton.

 The actin cytoskeleton, with the involvement of ACTB1, is responsible for various cellular processes such as cell shape maintenance, cell movement, intracellular transport, and cell division.

Mutations in ACTB1 have been implicated in Baraitser-Winter syndrome and autosomal dominant nonsyndromic deafness 20.

ACTB1 is predicted to be active in actin filament formation.

ACTB1 provides structural support and stability to the actin cytoskeleton.

ACTB1, as a component of the actin cytoskeleton, provides the necessary structure and dynamics for cell migration by facilitating the formation and remodeling of actin filaments at the leading edge of migrating cells.

ACTB1, as a key component of the actin cytoskeleton, is involved in facilitating intracellular transport by providing tracks for motor proteins to move along and by participating in the organization and dynamics of cellular transport pathways.

The localization of ACTB1 in dense bodies and focal adhesions suggests its involvement in cell structure and adhesion processes.

ACTB1 is involved in various cellular processes, such as cell migration, cell division, and intracellular transport.

ACTB1 is orthologous to the human gene ACTB (actin beta), which shares similarity and is involved in cytoskeletal organization and cellular processes.

ACTB1 expression in the eye suggests its involvement in maintaining the structural integrity and function of ocular tissues, such as the lens and the retina.

ACTB1 is predicted to be located in several cellular components, including the actin cytoskeleton, dense body, and focal adhesion.

ACTB1 likely plays a role in the cytoskeletal organization and cellular processes of hematopoietic cells, which are responsible for the production and maturation of blood cells.

Dysregulation of ACTB1 expression in the liver, such as elevated levels observed in certain cancers, may contribute to liver tumorigenesis and affect cellular processes related to liver function and metabolism.

ACTB1 is expressed in several structures and tissues, including the eye, hematopoietic cells, liver, male organism, and pleuroperitoneal region.

In addition to Baraitser-Winter syndrome and autosomal dominant nonsyndromic deafness 20, mutations in ACTB1 have also been associated with other conditions such as dilated cardiomyopathy and intellectual disability.

ACTB1 plays a role in focal adhesion, which is important for cell adhesion to the extracellular matrix and for transmitting mechanical signals between the cell and its environment.

The involvement of ACTB1 in the pleuroperitoneal region suggests its potential role in the development and maintenance of tissues in this region, which includes the membranes surrounding the lungs and the peritoneal cavity.

Mutations in ACTB1 can disrupt the normal function of the actin cytoskeleton, leading to the characteristic features and brain abnormalities observed in Baraitser-Winter syndrome.

 ACTB1 is involved in DNA repair processes through its association with actin-related proteins, which participate in chromatin remodeling and facilitate DNA repair activities.