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  • Official Full Name
  • 2-aminoethanethiol (cysteamine) dioxygenase
  • Background
  • Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase;(ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to;form hypotaurine (Dominy et al., 2007 (PubMed 17581819)).
  • Synonyms
  • ADO; 2-aminoethanethiol (cysteamine) dioxygenase; C10orf22, chromosome 10 open reading frame 22; 2-aminoethanethiol dioxygenase; cysteamine dioxygenase; FLJ14547; cysteamine (2-aminoethanethiol) dioxygenase (ADO); C10orf22; DKFZp564C046
Cat.#:ADO-366HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADO Protein, GST-tagged
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Cat.#:ADO-1369MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ADO Protein
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Cat.#:ADO-253RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ADO Protein, His-tagged
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Cat.#:ADO-9007HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ADO 293 Cell Lysate
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Involved Pathway

ADO involved in several pathways and played different roles in them. We selected most pathways ADO participated on our site, such as Taurine and hypotaurine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Taurine and hypotaurine metabolism
GAD1; CDO1; GGT7; GGT5A; GGT5; BAAT; GAD1B; ADOB; CSAD; GGT1A
Metabolic pathways
ACER1; PIGL; NDUFB2; FUT2; CYP19A1B; XYLB; NDST1; GALNTL2; GRHPR; PIGK

Protein Function

ADO has several biochemical functions, for example, cysteamine dioxygenase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADO itself. We selected most functions ADO had, and list some proteins which have the same functions with ADO. You can find most of the proteins on our site.
Function
Related Protein
Function cysteamine dioxygenase activity
Related Protein ADO
Function metal ion binding
Related Protein IMPDH1A; STEAP3; HBB-Y; PVALB1; ZBTB46; PRKCZ; ZNF554; LHX8; ZNF502; ZGPAT

Interacting Protein

ADO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADO here. Most of them are supplied by our site. Hope this information will be useful for your research of ADO.
FYCO1

ADO Related Articles

Ahmed, S; Sami, A; et al. HER2-directed therapy: current treatment options for HER2-positive breast cancer. BREAST CANCER 22:101-116(2015).
Carneiro, BA; Meeks, JJ; et al. Emerging therapeutic targets in bladder cancer. CANCER TREATMENT REVIEWS 41:170-178(2015).