AMPD1

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AMPD1

Official Full Name adenosine monophosphate deaminase 1
Background Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Synonyms AMPD1; adenosine monophosphate deaminase 1; adenosine monophosphate deaminase 1 (isoform M); AMP deaminase 1; AMPD isoform M; MAD; MADA; skeletal muscle AMPD; AMPD; myoadenylate deaminase; adenosine monophosphate deaminase-1 (muscle)
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • HEK293T Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Ampd1-1615M Recombinant Mouse Ampd1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human AMPD1-8877H Recombinant Human AMPD1 protein, MYC/DDK-tagged HEK293T Cells Myc/DDK
    Human AMPD1-3428H Recombinant Human AMPD1, His-tagged E.Coli or Yeast His
    Human AMPD1-754H Recombinant Human AMPD1 protein, GST-tagged Wheat Germ GST
    Human AMPD1-8877HCL Recombinant Human AMPD1 293 Cell Lysate HEK293 N/A
    Rat Ampd1-3429R Recombinant Rat Ampd1, His-tagged E.Coli or Yeast His
    Rat AMPD1-657R Recombinant Rat AMPD1 Protein Mammalian Cell His
    Zebrafish AMPD1-11138Z Recombinant Zebrafish AMPD1 Mammalian Cell His

    AMPD1 involved in several pathways and played different roles in them. We selected most pathways AMPD1 participated on our site, such as Purine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMPD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism NME2A; AMPD2; FHIT; PDE4A; PRPS1B; NME1; PKM2; RRM2B; HDDC3; PKLR
    Metabolic pathways TPI1A; ST6GAL1; GLCE; HPSE; SAT1A.1; AZIN2; AMPD3B; ATP6AP1B; LPIN1; PLA2G3

    AMPD1 has several biochemical functions, for example, AMP deaminase activity, metal ion binding, myosin heavy chain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMPD1 itself. We selected most functions AMPD1 had, and list some proteins which have the same functions with AMPD1. You can find most of the proteins on our site.

    Function Related Protein
    AMP deaminase activity AMPD3B; AMPD1; AMPD2; AMPD3
    metal ion binding PPP4CA; ZNF821; KCNIP3A; IGFBP3; NUDT19; MUTYH; GALNT10; MGAT1; C6AST4; ARG2
    myosin heavy chain binding PDLIM2; AMPD1; CORO1A; MYBPC3; MYL12B; MYL9; MYL2

    AMPD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMPD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AMPD1.

    C1QTNF9; GABARAP; MAP1LC3B; GABARAPL1; MAP1LC3A

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