alox8
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  • Official Full Name
  • arachidonate 8-lipoxygenase
  • Synonyms
  • ALOX8;arachidonate 8-lipoxygenase;ENSMUSG00000020891;8-LOX;8S-LOX;Alox15b;11;11 B4;arachidonate 15-lipoxygenase B;arachidonate 15-lipoxygenase B;15-LOX-2;15-LOX-B;8S-lipoxygenase;15-lipoxygenase 2;arachidonate 15-lipoxygenase type II;arachidonate 15-lipoxygenase, second type;EC 1.13.11.33;
Cat.#:ALOX8-1569MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ALOX8 Protein
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Involved Pathway

Alox8 involved in several pathways and played different roles in them. We selected most pathways Alox8 participated on our site, such as Arachidonic acid metabolism, Metabolic pathways, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Alox8 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Arachidonic acid metabolism
PLA2G4A; ALOX5AP; ALOX8; GPX7; CYP4A11; DPEP2; GPX5; CYP2Y3; CYP2J6; ALOX15B
Metabolic pathways
PLA2G12A; B3GNT2; PIGC; PPAP2C; FUT2; NDUFS1; ADSSL1; PYCRL; MAOA; PDHA2
Serotonergic synapse
HTR3C; PLA2G4F; NRAS; PTGS1; PLCB2; SLC18A2; PLA2G4C; CYP2C39; ITPR3; ALOX8

Protein Function

Alox8 has several biochemical functions, for example, 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity, 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity, 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Alox8 itself. We selected most functions Alox8 had, and list some proteins which have the same functions with Alox8. You can find most of the proteins on our site.
Function
Related Protein
Function 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity
Related Protein ALOX8
Function 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity
Related Protein ALOX8
Function 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity
Related Protein ALOX8
Function 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity
Related Protein ALOX8
Function 2-aminobiphenyl-2,3-diol 1,2-dioxygenase activity
Related Protein ALOX8
Function 2,2,3-trihydroxybiphenyl dioxygenase activity
Related Protein ALOX8
Function 2,3-dihydroxy DDT 1,2-dioxygenase activity
Related Protein ALOX8
Function 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity
Related Protein ALOX8
Function 2,3-dihydroxy-p-cumate dioxygenase activity
Related Protein ALOX8
Function 2,3-dihydroxydiphenyl ether dioxygenase activity
Related Protein ALOX8
Function 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity
Related Protein ALOX8
Function 2-aminophenol 1,6-dioxygenase activity
Related Protein ALOX8
Function 2-mercaptobenzothiazole dioxygenase activity
Related Protein ALOX8
Function 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity
Related Protein ALOX8
Function 3,4-dihydroxyphenanthrene dioxygenase activity
Related Protein ALOX8
Function 3,5-dichlorocatechol 1,2-dioxygenase activity
Related Protein ALOX8
Function 3-hydroxy-2-naphthoate 2,3-dioxygenase activity
Related Protein ALOX8
Function 4,5-dihydroxybenzo(a)pyrene dioxygenase activity
Related Protein ALOX8
Function 4,5-dihydroxypyrene dioxygenase activity
Related Protein ALOX8
Function 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity
Related Protein ALOX8
Function 4-hydroxycatechol 1,2-dioxygenase activity
Related Protein ALOX8
Function 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity
Related Protein ALOX8
Function 5-aminosalicylate dioxygenase activity
Related Protein ALOX8
Function 7,8-dihydroxy benzo(a)pyrene dioxygenase activity
Related Protein ALOX8
Function 9,10-dihydroxybenzo(a)pyrene dioxygenase activity
Related Protein ALOX8
Function arachidonate 15-lipoxygenase activity
Related Protein ALOX8; ALOX15B; ALOX15
Function arachidonate 8(R)-lipoxygenase activity
Related Protein ALOX8
Function arachidonate 8(S)-lipoxygenase activity
Related Protein ALOX8; ALOX15B
Function benzo(a)pyrene 11,12-dioxygenase activity
Related Protein ALOX8
Function benzo(a)pyrene 4,5-dioxygenase activity
Related Protein ALOX8
Function benzo(a)pyrene 7,8-dioxygenase activity
Related Protein ALOX8
Function benzo(a)pyrene 9,10-dioxygenase activity
Related Protein ALOX8
Function calcium ion binding
Related Protein ZZEF1; PLCD1B; MAN1A1; PPP2R3A; MMP16; ACTN2; HPCAL1; S100B; GUCA1E; HPCA
Function carbazole 1,9a-dioxygenase activity
Related Protein ALOX8
Function catechol dioxygenase activity
Related Protein ALOX8
Function chlorocatechol 1,2-dioxygenase activity
Related Protein ALOX8
Function dihydroxydibenzothiophene dioxygenase activity
Related Protein ALOX8
Function dihydroxyfluorene dioxygenase activity
Related Protein ALOX8
Function dioxygenase activity
Related Protein ALOX5A; MINA; BCO1; ASPHD1; ALKBH7; KDM4D; KDM4C; KDM3B; ALOX5B.2; PTGS2
Function diphenyl ether 1,2-dioxygenase activity
Related Protein ALOX8
Function hydroquinone 1,2-dioxygenase activity
Related Protein ALOX8
Function iron ion binding
Related Protein PAH; CYP4V7; EGLN1; CYP2H1; CYP2N13; HBAD; CYP2A7; TPH1A; TMEM195; CYP4A14
Function linoleate 13S-lipoxygenase activity
Related Protein ALOX12; ALOX15B; ALOX8
Function lipid binding
Related Protein ACBD4; FABP11A; APODA.2; SEC14L3; FABP1A; CRABP2A; DNM1L; PEX3; CYTH1; GLTP
Function metal ion binding
Related Protein CYBASC3; CBFA2T3; HGS; ITGA7; APTX; DPF2L; ZFP804A; CREB5; NAALADL1; SP7
Function oxidoreductase activity
Related Protein ALDH3A2B; KDM1A; RDH8B; G6PDX; SRD5A3; SDR16C5A; NOS2B; CYP19A1B; GFOD2; GPX4A
Function oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Related Protein P4HA2; ALOX5B.2; ALOX12E; ADOB; ALOX12B; P4HA3; BCO2; P4HA1B; ALOX5B.3; ADOA
Function p-cumate 2,3-dioxygenase activity
Related Protein ALOX8
Function phenanthrene dioxygenase activity
Related Protein ALOX8
Function phenanthrene-4-carboxylate dioxygenase activity
Related Protein ALOX8
Function protocatechuate 3,4-dioxygenase type II activity
Related Protein ALOX8
Function pyrene dioxygenase activity
Related Protein ALOX8
Function pyridine-3,4-diol dioxygenase activity
Related Protein ALOX8
Function styrene dioxygenase activity
Related Protein ALOX8
Function tetrachlorobenzene dioxygenase activity
Related Protein ALOX8

Alox8 Related Articles

Kawajiri, H; Piao, YS; et al. Synthesis of 8,9-leukotriene A(4) by murine 8-lipoxygenase. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 338:144-148(2005).
Furstenberger, G; Marks, F; et al. Arachidonate 8(S)-lipoxygenase. PROSTAGLANDINS & OTHER LIPID MEDIATORS 68-9:235-243(2002).