CBX4

  • Official Full Name

    chromobox homolog 4
  • Synonyms

    CBX4;chromobox homolog 4;chromobox homolog 4 (Drosophila Pc class);E3 SUMO-protein ligase CBX4;hPC2;NBP16;NS5ATP1 binding protein 16;Pc class 2 homolog (Drosophila);PC2;Pc class 2 homolog;polycomb 2 homolog;NS5ATP1-binding protein 16;chromobox
Cat.# Product name Source (Host) Species Tag Protein Length Price
CBX4-10769H Recombinant Human CBX4, GST-tagged E.coli Human GST 1-290a.a.
CBX4-0482H Recombinant Human CBX4 Protein, GST-Tagged Wheat Germ Human GST
CBX4-11764Z Recombinant Zebrafish CBX4 Mammalian Cells Zebrafish His
CBX4-6210C Recombinant Chicken CBX4 Mammalian Cells Chicken His
CBX4-7803HCL Recombinant Human CBX4 293 Cell Lysate HEK293 Human Non
CBX4-2780HF Recombinant Full Length Human CBX4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 290 amino acids

    Involved Pathway

    CBX4 involved in several pathways and played different roles in them. We selected most pathways CBX4 participated on our site, such as C-MYB transcription factor network,Cellular Senescence,Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular responses to stress DNAJC7,UBN1,TXN2,HIF1AN,HSBP1A,HIST3H2BB,AGO3,LAMTOR2,PHC3,EGLN1B
    SUMO E3 ligases SUMOylate target proteins NSMCE1,PHC3,PHC2,PHC1,CBX8,SMC6,SMC5,EID3,RING1,SCMH1
    Regulation of retinoblastoma protein GSC,MYOD1,ELF1,BRD2,ATF7,SMARCB1,BGLAP,AATF,CKM
    Post-translational protein modification DPAGT1,SMC5,ADAMTS15,MUC5AC,PIGK,SAE1,ST6GALNAC1.2,TRAPPC6B,B3GNT6,ARSF
    Oxidative Stress Induced Senescence SUZ12B,SUZ12A,PHC3,RNF2,BMI1B,TNIK,EED,CBX8A,SUZ12,PHC1
    Cellular Senescence HIST3H2BB,BMI1B,CABIN1,HIST1H1A,H1F0,RBBP7,SUZ12B,EHMT2,CBX6,CDKN2D
    C-MYB transcription factor network TOM1,LECT2,CEBPA,MYOD1,SMARCA2,CSF1R,CDK6,CREBBP,SKI,SLC25A3
    Metabolism of proteins ODAM,FBXW9,IGFBP6A,TOMM20,GALNT5,GNE,PIGK,MUC13,CTSH,CPB2

    Protein Function

    CBX4 has several biochemical functions, for example, SUMO binding,SUMO transferase activity,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBX4 itself. We selected most functions CBX4 had, and list some proteins which have the same functions with CBX4. You can find most of the proteins on our site.

    Function Related Protein
    transcription regulatory region DNA binding TFEB,BCL11B,KCNA3,NCOR1,SALL3B,TBP,FOXA1,CITED1,SP1,PAX2
    phosphoprotein binding SRC,PRKCSH,RB1,SNCA,TRPV1,YWHAB,PAFAH1B1,SERPINB1A,TOX3,SFN
    single-stranded RNA binding TLR7,SNRPC,A1CF,ANXA1,DDX58,CBX7,POLR2G,IFIH1,AGO2,LSM14A
    transcription corepressor activity SSX1,SKOR2,HIPK2,SMYD1,MXD1,ARHGAP35,ZFPM1,HDAC5,JAZF1,WWTR1
    ligase activity RCHY1,RTCD1,TRIM22,ATG10,LIPT2,RNF130,RNF4,UBE2I,RNF123,MID2
    methylated histone binding MPHOSPH8,MTF2,ING3,PHF13,DPPA3,MSH6,CHD8,SPIN1,RAG2,JHDM1D
    chromatin binding NFATC2,TOP2A,MEIOB,CAPNS2,TMPOA,EWSR1A,LMO2,CDK9,CITED2,EP300
    SUMO transferase activity PIAS3,PIAS4,TOPORS,SUMO4,SUMO3,NSMCE2,UBE2I,SUMO1,UBE2IB,MUL1
    SUMO binding USP25,TDG,HERC2,RPS3,TOLLIP,USPL1,PML

    Interacting Protein

    CBX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBX4.

    BMI1;HIF1A

    Resources

    References

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