CBX4 Protein, chromobox homolog 4

CBX4

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CBX4

Official Full Name chromobox homolog 4
Synonyms CBX4; chromobox homolog 4; chromobox homolog 4 (Drosophila Pc class); E3 SUMO-protein ligase CBX4; hPC2; NBP16; NS5ATP1 binding protein 16; Pc class 2 homolog (Drosophila); PC2; Pc class 2 homolog; polycomb 2 homolog; NS5ATP1-binding protein 16; chromobox
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CBX4-0482H Recombinant Human CBX4 Protein, GST-Tagged Wheat Germ GST
    Human CBX4-10769H Recombinant Human CBX4, GST-tagged E.coli GST
    Human CBX4-7803HCL Recombinant Human CBX4 293 Cell Lysate HEK293 N/A
    Chicken CBX4-6210C Recombinant Chicken CBX4 Mammalian Cell His
    Zebrafish CBX4-11764Z Recombinant Zebrafish CBX4 Mammalian Cell His

    CBX4 involved in several pathways and played different roles in them. We selected most pathways CBX4 participated on our site, such as C-MYB transcription factor network, Cellular Senescence, Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network MYB; SKI; CEBPA; TRIM28; ADA; CDKN1B; MYC; PIAS3; CBX4; PRTN3
    Cellular Senescence HIST1H1B; POT1A; HTATIP; HIST3H2BB; MINK1; TERF2IP; MAPKAPK2B; CDKN2A; HIST1H1A; RBB4L
    Cellular responses to stress RBB4L; ATG4A; HSPA12B; PHC2; KAT5; ATG9A; EEF1A1; C7orf59; C11orf73; RING1
    Metabolism of proteins ADAMTSL1; ADAMTSL4; EXOC6; EXOSC8; PHC3; NAPG; IGFBP5; TRAPPC9; KIFC3; MGAT4A
    Oxidative Stress Induced Senescence SCMH1; PHC3; BMI1B; CBX8; TNIK; EED; PHC2; PHC1; SUZ12A; MINK1
    Post-translational protein modification SEC22A; TRAPPC6A; ADAMTS15; B3GALTL; EID3; PHC3; MUC20; PHC2; MAN1B1; CNIH
    Regulation of retinoblastoma protein ATF7; SMARCB1; CKM; ELF1; GSC; BRD2; CBX4; BGLAP; AATF; MYOD1
    SUMO E3 ligases SUMOylate target proteins RNF2; PHC2; NSMCE2; NSMCE1; PHC3; RING1; SMC5; CBX8; SCMH1; CBX4

    CBX4 has several biochemical functions, for example, SUMO binding, SUMO transferase activity, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBX4 itself. We selected most functions CBX4 had, and list some proteins which have the same functions with CBX4. You can find most of the proteins on our site.

    Function Related Protein
    SUMO binding CBX4; RPS3; PML; HERC2; USPL1; TOLLIP; TDG; USP25
    SUMO transferase activity UBE2I; SUMO1; SUMO3; SUMO4; MUL1; CBX4; PIAS3; UBE2IB; NSMCE2; TOPORS
    chromatin binding CAPNS2; CHAF1A; MNT; EP300; RCC1; CALCOCO1; TRP63; CHAF1B; EZH1; DNMT3A
    enzyme binding BCHE; VAPB; PUS7; CREB1; HLCS; YWHAB; PLAUR; CYP3A4; TSPAN17; CYP2A4
    ligase activity TTLL11; MKRN1; TOPORS; UBR5; PCXA; TRIM39; ITCH; TRAF7; MUL1; TRIM21
    methylated histone binding MSH6; FAM156A; PHF13; ING3; PHF8; SPIN1; ING4; UHRF1; LOXL2; TP53BP1
    phosphoprotein binding SERPINB1A; SRC; CSNK1D; TOX3; PKD2; RB1; THRAP3; LRP11; MID2; SAG
    protein binding PCSK5; HRASLS5; KIAA0408; TNFRSF1A; APLP1; IWS1; MELK; SPG11; MED20; TAF15
    single-stranded RNA binding DLX2; IFIH1; AGO3; LUZP4; CBX7; HNRNPA1; CNBP; TLR7; PIWIL1; AGO2
    transcription corepressor activity BATF3; PIAS1; MXD1; ATF3; NR0B2; TRIM22; CITED2; NOC2L; E2F8; SUFU
    transcription regulatory region DNA binding TBP; BCL11B; GLIS2; WNT1; THRA; ETV5; MTERFD1; MEN1; GATA4; ARRB1

    CBX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBX4.

    BMI1; HIF1A

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