CBX4

  • Official Full Name

    chromobox homolog 4
  • Synonyms

    CBX4;chromobox homolog 4;chromobox homolog 4 (Drosophila Pc class);E3 SUMO-protein ligase CBX4;hPC2;NBP16;NS5ATP1 binding protein 16;Pc class 2 homolog (Drosophila);PC2;Pc class 2 homolog;polycomb 2 homolog;NS5ATP1-binding protein 16;chromobox
Cat.# Product name Source (Host) Species Tag Protein Length Price
CBX4-10769H Recombinant Human CBX4, GST-tagged E.coli Human GST 1-290a.a.
CBX4-11764Z Recombinant Zebrafish CBX4 Mammalian Cells Zebrafish His
CBX4-6210C Recombinant Chicken CBX4 Mammalian Cells Chicken His
CBX4-7803HCL Recombinant Human CBX4 293 Cell Lysate HEK293 Human Non
CBX4-2780HF Recombinant Full Length Human CBX4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 290 amino acids

    Involved Pathway

    CBX4 involved in several pathways and played different roles in them. We selected most pathways CBX4 participated on our site, such as C-MYB transcription factor network,Cellular Senescence,Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative Stress Induced Senescence MINK1,PHC1,SCMH1,CBX8A,PHC2,CBX6,BMI1A,BMI1B,RNF2,CBX8
    Cellular responses to stress EGLN1B,CDKN2B,ATG9A,AMBRA1A,H3F3B.1,ERF,POT1,TXN,CABIN1,GABARAP
    Post-translational protein modification MAGT1,EIF5A,CNIH2,UBA2,ADAMTS5,TMED2,ADAMTSL5,PIGK,PHC1,SPON1A
    C-MYB transcription factor network MYOD1,PRTN3,SMARCA2,CDKN1B,CEBPB,PPID,TRIM28,PTCRA,LECT2,CLTA
    Cellular Senescence PHC3,EP400,HMGA1-RS1,CDKN2A,AGO1,SCMH1,RNF2,POT1A,TINF2,CDK4
    Regulation of retinoblastoma protein CKM,BRD2,SMARCB1,AATF,MYOD1,BGLAP,ATF7,GSC,ELF1
    Metabolism of proteins GATA6,MUC5AC,ATPBD4,IGFBP4,TBCE,SEC63,DPAGT1,B3GNT3,IGFBP6A,DPH3
    SUMO E3 ligases SUMOylate target proteins SCMH1,EID3,NSMCE2,PHC3,PHC1,PHC2,RNF2,NSMCE1,SMC6,NSMCE4A

    Protein Function

    CBX4 has several biochemical functions, for example, SUMO binding,SUMO transferase activity,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBX4 itself. We selected most functions CBX4 had, and list some proteins which have the same functions with CBX4. You can find most of the proteins on our site.

    Function Related Protein
    phosphoprotein binding GPRIN1,SRC,THRAP3,SFN,DPYS,MID1,YWHAE,TOX3,DPYSL3,PRKCSH
    methylated histone binding ING2,MSL3,RAG2,ING3,CBX8,MTF2,LOXL2,SUZ12,SPIN1,ING4
    single-stranded RNA binding AGO2,CNBP,LSM14A,HNRNPA1,HNRNPF,DDX58,STRBP,A1CF,IFIT5,HMGB1
    transcription corepressor activity HIRA,ZNF274,CCND1,NAB2,TFAP2B,SKOR1A,C1QBP,MXD1,CBFA2T3,ENO1
    enzyme binding P4HB,CDK19,KRT79,CD40,HIST1H2AG,PDCD2,GBP1,TNKS2,LUC7L2,MAPK14
    SUMO binding TDG,PML,TOLLIP,USP25,USPL1,RPS3,HERC2
    SUMO transferase activity SUMO4,PIAS4,PIAS3,MUL1,UBE2IA,NSMCE2,SUMO3,TOPORS,UBE2IB,SUMO1
    protein binding RQCD1,METTL1,EIF4G1,ATP1A2,VAPB,AHSA2,MTNR1B,CCT4,TMEM59,HSPH1
    ligase activity MARCH8,TRIM56,UCHL1,DTX1,TRIM24,RNF144AB,ZSWIM2,TRIM31,HECW1,TTLL4

    Interacting Protein

    CBX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBX4.

    BMI1;HIF1A

    Resources

    References

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