CCT7

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CCT7

Official Full Name chaperonin containing TCP1, subunit 7 (eta)
Background This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.
Synonyms CCT7; chaperonin containing TCP1, subunit 7 (eta); T-complex protein 1 subunit eta; Ccth; Nip7 1; CCT ETA; CCT-eta; Chaperonin containing t complex polypeptide 1 eta subunit; Chaperonin containing TCP1 subunit 7 (eta); Chaperonin containing TCP1 subunit 7; HIV 1 Nef interacting protein; HIV-1 Nef-interacting protein; T complex protein 1 eta subunit; TCP-1-eta; TCPH_HUMAN; OTTHUMP00000202321; OTTHUMP00000202322; OTTHUMP00000213063; HIV-1 Nef interacting protein; chaperonin containing t-complex polypeptide 1, eta subunit; CCTETA; NIP7-1; TCP1ETA
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCT7-0717H Recombinant Human CCT7 Protein, GST-Tagged Wheat Germ GST
    Human CCT7-10900H Recombinant Human CCT7, His-tagged E.coli His
    Human CCT7-3007H Recombinant Human CCT7 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CCT7-313HCL Recombinant Human CCT7 cell lysate N/A
    Mouse CCT7-3029M Recombinant Mouse CCT7 Protein Mammalian Cell His
    Rhesus Macaque CCT7-715R Recombinant Rhesus monkey CCT7 Protein, His-tagged Mammalian Cell His
    Chicken CCT7-3185C Recombinant Chicken CCT7 Mammalian Cell His
    Zebrafish CCT7-9522Z Recombinant Zebrafish CCT7 Mammalian Cell His

    CCT7 involved in several pathways and played different roles in them. We selected most pathways CCT7 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCT7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Association of TriC/CCT with target proteins during biosynthesis CCT8; CCT6A; CCT3; FKBP9; TCP1; FBXW4; CCT4; FBXL5; FBXW5; CCT5
    Chaperonin-mediated protein folding CCT7; PFDN6; CCT6A; TUBA3D; VBP1; PFDN1; PFDN5; TUBB4A; CCT4; CCT8
    Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding CCT8; PFDN5; TUBA1B; TUBB4B; TUBB4A; CCT5; CCT4; PFDN6; CCT6A; PFDN4
    Folding of actin by CCT/TriC CCT6A; CCT7; CCT4; TCP1; CCT3; CCT5; CCT8; CCT2
    Formation of tubulin folding intermediates by CCT/TriC CCT7; TUBB4B; TCP1; CCT8; TUBB4A; CCT2; CCT4; CCT6A; CCT5; TUBA3D
    Metabolism of proteins CGB7; YY2; MFGE8; TIMM17B; B3GNT8; CGB5; CPN1; CBX8; ALG14; NAPAA
    Prefoldin mediated transfer of substrate to CCT/TriC PFDN2; VBP1; PFDN4; PFDN5; PFDN6; CCT6A; PFDN1; CCT7
    Protein folding SERPINA7; CCT7; PFDN6; FKBP9; FBXW9; PFDN2; FBXL5; TBCA; PFDN4; TBCE

    CCT7 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by CCT7 itself. We selected most functions CCT7 had, and list some proteins which have the same functions with CCT7. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding GM7168; RTCB; SLFNL1; PAK7; ERBB2; RYK; SPATA5; DMC1; TARS; TTLL3
    identical protein binding VWA1; ZNHIT6; PIK3AP1; SERPINA1E; EID3; RUVBL2; STAC3; MMP9; KCNH2; CRYAA
    protein binding DST; FANCF; BLVRA; UBAP1; STK39; GAPDHS; ATP2B4; MYBBP1A; RBM5; CCDC123
    unfolded protein binding CLPX; CDC37; CCT5; HSPA9; CHAF1B; TAPBP; DNAJB11; HSPA5; CRYAB; ERLEC1

    CCT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCT7.

    PPP4C; PPP2CB; PPP2CA; STRN3; ILK; SSSCA1; STRN

    Erdmann, J; Stark, K; et al. Dysfunctional nitric oxide signalling increases risk of myocardial infarction. NATURE 504:432-+(2013).
    Hirata, H; Ishinabe, S; et al. Molecular Characterization and Phylogenetic Analysis of Babesia sp NV-1 Detected from Wild American Mink (Neovison vison) in Hokkaido, Japan. JOURNAL OF PARASITOLOGY 99:350-352(2013).

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