CCT7
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Official Full Name
chaperonin containing TCP1, subunit 7 (eta)
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Overview
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. -
Synonyms
CCT7; chaperonin containing TCP1, subunit 7 (eta); T-complex protein 1 subunit eta; Ccth; Nip7 1; CCT ETA; CCT-eta; Chaperonin containing t complex polypeptide 1 eta subunit; Chaperonin containing TCP1 subunit 7 (eta); Chaperonin containing TCP1 subunit 7; HIV 1 Nef interacting protein; HIV-1 Nef-interacting protein; T complex protein 1 eta subunit; TCP-1-eta; TCPH_HUMAN; OTTHUMP00000202321; OTTHUMP00000202322; OTTHUMP00000213063; HIV-1 Nef interacting protein; chaperonin containing t-complex polypeptide 1, eta subunit; CCTETA; NIP7-1; TCP1ETA;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- MYC
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- CCT7 Related Articles
CCT7 involved in several pathways and played different roles in them. We selected most pathways CCT7 participated on our site, such as Association of TriC/CCT with target proteins during biosynthesis, Chaperonin-mediated protein folding, Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCT7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Association of TriC/CCT with target proteins during biosynthesis | FBXW2;FBXW5;CCT4;FKBP9;FBXW4;NOP56;CCT5;TCP1;CCT8 |
| Chaperonin-mediated protein folding | CCT3;TUBB4A;FBXL5;TUBB4B;TUBA3D;PFDN6;KIFC3;FBXW2;CCT2 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | TUBA1B;CCT3;CCT7;PFDN5;CCT6A;PFDN1;CCT8;TUBB4A;CCT4 |
| Folding of actin by CCT/TriC | CCT8;CCT4;CCT7;TCP1;CCT6A;CCT5;CCT2;CCT3 |
| Formation of tubulin folding intermediates by CCT/TriC | CCT6A;CCT8;CCT2;TUBA1B;CCT4;TUBA3D;TUBB4A;CCT5;TCP1 |
| Metabolism of proteins | SPCS3;PHC3;KDELR3;ARL2;SSPO;PAPPA;CNIH;LMAN2;IGFBP4 |
| Prefoldin mediated transfer of substrate to CCT/TriC | CCT7;PFDN6;CCT6A;PFDN2;PFDN1;VBP1;PFDN4;PFDN5 |
| Protein folding | VBP1;FKBP9;TBCD;KIFC3;TBCB;CCT7;FBXW9;ARL2;PFDN5 |
CCT7 has several biochemical functions, for example, ATP binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCT7 itself. We selected most functions CCT7 had, and list some proteins which have the same functions with CCT7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ERN2;CHD1;TRIO;PIK3C3;TARS;MTHFD1B;EPHA2A;KIF15;PAPD4 |
| identical protein binding | AGER;RAD51;HOOK3;GOT1;UHRF1;APOA1;ZNF3;SLC22A1;AMELX |
| protein binding | C1QTNF1;ZGPAT;SH3RF2;ILVBL;SLIRP;NFKBIB;MYLK2;EPHB4;TTLL10 |
| unfolded protein binding | TCP1;DNAJB13;H2-KE2;CALR;HSP90AA1.2;PPIA;PPIB;AIP;CRYAB |
CCT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCT7.
PPP4C; PPP2CB; PPP2CA; STRN3; ILK; SSSCA1; STRN
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