COL27A1 Protein, COL27A1 collagen, type XXVII, alpha 1 [ Homo sapiens ]

COL27A1

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COL27A1

Official Full Name COL27A1 collagen, type XXVII, alpha 1 [ Homo sapiens ]
Background Fibrillar collagens, such as COL27A1, compose one of the most ancient families of extracellular matrix molecules. They form major structural elements in extracellular matrices of cartilage, skin, and tendon (Boot-Handford et al., 2003 [PubMed 12766169]).
Synonyms collagen, type XXVII, alpha 1; KIAA1870; FLJ11895; MGC11337; collagen alpha-1(XXVII) chain; COL27A1
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COL27A1-11431H Recombinant Human COL27A1, GST-tagged E.coli GST
    Mouse COL27A1-3731M Recombinant Mouse COL27A1 Protein Mammalian Cell His
    Rat COL27A1-1520R Recombinant Rat COL27A1 Protein Mammalian Cell His

    COL27A1 involved in several pathways and played different roles in them. We selected most pathways COL27A1 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL27A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway TLR2; CREB5; ITGAV; IKBKB; NR4A1; THBS1; PRL; PIK3R5; RPTOR; PRKAA1
    Focal adhesion FYNB; GRB2B; SRC; COL5A1; THBS3A; MYLK2; RAC1A; RAP1AA; RAF1A; TESK2
    ECM-receptor interaction Itga10&Itgb1; COL1A1; THBS3; COL6A6; FN1A; ITGB5; ITGB6; LAMA2; ITGA2; ITGB1B.2
    Platelet activation ITGA2B; APBB1IP; PTGS1; PLA2G4C; GNAI1; PIK3R1; GUCY1A3; FERMT3; PRKACA; MAPK11
    Protein digestion and absorption COL7A1; CELA2B; SLC8A1; SLC3A1; CPA2; MEP1A; COL10A1; COL24A1; COL18A1; ATP1B4
    Amoebiasis PIK3R2; MUC2; IL6; CXCL1; COL3A1; TGFB1; TLR4; ITGB2; SERPINB1A; PRKCB

    COL27A1 has several biochemical functions, for example, extracellular matrix structural constituent, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL27A1 itself. We selected most functions COL27A1 had, and list some proteins which have the same functions with COL27A1. You can find most of the proteins on our site.

    Function Related Protein
    extracellular matrix structural constituent COL4A4; COL27A1A; COL8A2; OPTC; COMP; COL4A6; MATN1; COL3A1; COL1A1A; CHI3L1
    metal ion binding HELZ2; PDE6B; KLF2; JAZF1B; STK25; ATP1A3A; PRR3; ZKSCAN3; HIVEP2A; CSNK2B

    COL27A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL27A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL27A1.

    Dlg4

    Gonzaga-Jauregui, C; Gamble, CN; et al. Mutations in COL27A1 cause Steel syndrome and suggest a founder mutation effect in the Puerto Rican population. EUROPEAN JOURNAL OF HUMAN GENETICS 23:342-346(2015).
    Scharf, JM; Yu, D; et al. Genome-wide association study of Tourette's syndrome. MOLECULAR PSYCHIATRY 18:721-728(2013).

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