CPEB1 Protein, cytoplasmic polyadenylation element binding protein 1


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Official Full Name cytoplasmic polyadenylation element binding protein 1
Background This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3 UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms CPEB1; cytoplasmic polyadenylation element binding protein 1; cytoplasmic polyadenylation element-binding protein 1; CPEB; FLJ13203; CPE-binding protein 1; CPE-BP1; CPEB 1; CPEB1 protein; CPEB1_HUMAN; Cytoplasmic polyadenylation binding protein 1; Cytoplasmic polyadenylation element binding protein; h-CEBP; hCPEB-1; mKIAA0940; MKIAA0940 protein; CEBP
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Cpeb1-932M Recombinant Mouse Cpeb1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CPEB1-11516H Recombinant Human CPEB1, GST-tagged E.coli GST
    Human CPEB1-166H Recombinant Human CPEB1, His-tagged E.coli His
    Human CPEB1-1781H Recombinant Human CPEB1 Protein, GST-tagged Wheat Germ GST
    Human CPEB1-625H Recombinant Human CPEB1 Protein, His-tagged E.coli His
    Human CPEB1-7316HCL Recombinant Human CPEB1 293 Cell Lysate HEK293 N/A
    Human CPEB1-7317HCL Recombinant Human CPEB1 293 Cell Lysate HEK293 N/A
    Human CPEB1-903H Recombinant Human CPEB1 Protein, GST-His-tagged E.coli GST/His
    Mouse CPEB1-3837M Recombinant Mouse CPEB1 Protein Mammalian Cell His
    Rhesus Macaque CPEB1-1002R Recombinant Rhesus monkey CPEB1 Protein, His-tagged Mammalian Cell His
    Chicken CPEB1-5552C Recombinant Chicken CPEB1 Mammalian Cell His

    CPEB1 involved in several pathways and played different roles in them. We selected most pathways CPEB1 participated on our site, such as Oocyte meiosis, Dorso-ventral axis formation, Progesterone-mediated oocyte maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPEB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oocyte meiosis SMC3; CDC23; CALM4; PRKACAB; RBX1; CPEB1B; MAPK12B; PLK1; PPP3R2; RPS6KA1
    Dorso-ventral axis formation EGFRA; PIWIL2; CPEB1A; GRB2B; SPIRE1; CPEB3; ETV6; PIWIL4; FMN2; ETS2
    Progesterone-mediated oocyte maturation PRKACBB; RPS6KA1; MAPK12; PLK1; MAPK10; CDC27; PIK3CB; MAPK14A; RPS6KA3B; ANAPC7

    CPEB1 has several biochemical functions, for example, mRNA 3-UTR AU-rich region binding, mRNA 3-UTR binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPEB1 itself. We selected most functions CPEB1 had, and list some proteins which have the same functions with CPEB1. You can find most of the proteins on our site.

    Function Related Protein
    mRNA 3-UTR AU-rich region binding ELAVL1; CPEB3; CPEB1B; ZFP36; CPEB1; CPSF1; CPEB2
    metal ion binding KLF16; ZIC2A; PVALB3; MARCH9; RBM27; ZFP35; SUMF1; ZNF624; KARS; ZFR
    nucleotide binding G3BP2; RHOGD; TRNAU1AP; ATP2B1; PANK1A; RBM4.3; TTLL5; MCM3L; STK35L; CNGA4
    ribosome binding PPP1R2P9; EIF2S1B; ETF1; CPEB4; EIF3K; ICT1; SEC61B; NARG1; HSPA5; EIF2S1
    translation factor activity, RNA binding EEF2K; EIF2S3; EIF4G3; EIF5; CPEB3; CPEB4; EIF4E2; EIF2S2; CPEB1; GTF2H2
    translation repressor activity, nucleic acid binding CELF1; CPEB1B; PURA; CELF4; PPP1R2P9; CPEB2; CPEB4; PAIP2B; CPEB3; CPEB1

    CPEB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPEB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPEB1.


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