CPEB2 Protein, cytoplasmic polyadenylation element binding protein 2


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Official Full Name cytoplasmic polyadenylation element binding protein 2
Background The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Synonyms CPEB2; cytoplasmic polyadenylation element binding protein 2; cytoplasmic polyadenylation element-binding protein 2; CPE binding protein 2; CPE BP2; CPEBP2; hCPEB2; OTTHUMP00000115833; OTTHUMP00000115834; OTTHUMP00000217612; OTTHUMP00000217613; OTTHUMP00000217614; CPE-binding protein 2; CPEB-2; CPE-BP2; hCPEB-2
    • Species :
    • Human
    • Source :
    • E.coli
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CPEB2-11517H Recombinant Human CPEB2, His-tagged E.coli His

    CPEB2 involved in several pathways and played different roles in them. We selected most pathways CPEB2 participated on our site, such as Dorso-ventral axis formation, Oocyte meiosis, Progesterone-mediated oocyte maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPEB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Dorso-ventral axis formation GRB2A; EGFRA; GRB2B; CPEB1A; PIWIL2; NOTCH2; SPIRE1; CPEB2; ETS1; ETV7
    Progesterone-mediated oocyte maturation PGR; PIK3CB; MAPK13; CPEB4; PIK3CA; MAPK14A; CDC25C; AKT2; CPEB3; CDC27

    CPEB2 has several biochemical functions, for example, GTPase inhibitor activity, mRNA 3-UTR AU-rich region binding, mRNA 3-UTR binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPEB2 itself. We selected most functions CPEB2 had, and list some proteins which have the same functions with CPEB2. You can find most of the proteins on our site.

    Function Related Protein
    GTPase inhibitor activity TNK2; CDC42SE1; GPS1; CPEB2; ARL2; RTKN; GPS2; RHOH; PDE6D; IPO5
    mRNA 3-UTR AU-rich region binding CPEB3; ELAVL1; ZFP36; CPEB2; CPSF1; CPEB1B; CPEB1
    nucleotide binding EWSR1A; NIM1; RBM24; RBMY1B; GNA13A; ZNF638; DNAHC8; CPS1; CLCN4-2; ACSL1
    poly(A) RNA binding NSA2; YTHDC1; MARK2; CSTF2T; HEATR6; EIF4B; HIST1H4D; SSB; ANKHD1; ZYX
    poly-pyrimidine tract binding CPEB2; U2AF2; PTBP1
    ribosomal large subunit binding MRRF; OLA1; RBM3; CPEB2; EIF6; MALSU1; NPM1; NMD3
    ribosomal small subunit binding ERAL1; NPM1; DDX3X; MTIF3; DHX29; NME1; PIM1; PTCD3; CPEB2
    ribosome binding HSPA5; C12orf65; EIF6; MTRF1; EFTUD1; NARG1; RPN2; IGHMBP2; CPEB4; EIF5A
    translation factor activity, RNA binding EIF4H; CPEB1A; EIF1AX; CPEB2; EIF2S2; EIF4G2; EEF1A2; CPEB4; EIF4G1; EIF2S3
    translation repressor activity, nucleic acid binding CELF1; PURA; CPEB1B; CELF4; CPEB1; CPEB4; PPP1R2P9; CPEB1A; PAIP2B; CPEB3

    CPEB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPEB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPEB2.

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