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Official Full Name copine I
Background Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins.
Synonyms CPNE1; copine I; copine-1; CPN1; Copine 1; Copine1; CopineI; COPN 1; COPN1; CPN 1; CPNE 1; MGC1142; OTTHUMP00000030775; OTTHUMP00000030776; OTTHUMP00000030778; OTTHUMP00000030784; OTTHUMP00000196688; OTTHUMP00000199602; OTTHUMP00000204169
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    • SUMO
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CPNE1-2151H Recombinant Human CPNE1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Cpne1-2289M Recombinant Mouse Cpne1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human CPNE1-396H Recombinant Human CPNE1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human CPNE1-6540H Recombinant Human CPNE1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CPNE1-6541H Recombinant Human CPNE1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CPNE1-001HCL Recombinant Human CPNE1 cell lysate Insect Cell N/A
    Human CPNE1-11525H Recombinant Human CPNE1, GST-tagged E.coli GST
    Human CPNE1-1792H Recombinant Human CPNE1 Protein, GST-tagged Wheat Germ GST
    Human CPNE1-26782TH Recombinant Human CPNE1, His-tagged E.coli His
    Human CPNE1-3319H Recombinant Human CPNE1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CPNE1-501H Recombinant Human CPNE1, None tagged Insect Cell N/A
    Human CPNE1-8646H Recombinant Human CPNE1, SUMO tagged Insect Cell SUMO
    Rhesus Macaque CPNE1-1006R Recombinant Rhesus monkey CPNE1 Protein, His-tagged Mammalian Cell His
    Chicken CPNE1-4058C Recombinant Chicken CPNE1 Mammalian Cell His
    Zebrafish CPNE1-10096Z Recombinant Zebrafish CPNE1 Mammalian Cell His

    CPNE1 involved in several pathways and played different roles in them. We selected most pathways CPNE1 participated on our site, such as Glycerophospholipid biosynthesis, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPNE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerophospholipid biosynthesis PNPLA8; PEMT; CEPT1A; CPNE3; PITPNB; CDIPT; PLB1; AGPAT1; PLA2G16; ABHD3
    Metabolism SLC25A15B; ITPKB; CTRB1; AZIN1; CYP4T8; COX5B; SACM1LA; TPMT.2; ACSF2; MED15
    Metabolism of lipids and lipoproteins CYP2R1; OSBP; CYP2V1; MED8; CPNE3; CPNE6; INSIG2; MED29; PPM1LB; CPNE1
    Phospholipid metabolism CDS1; ABHD3; ABHD4; AWAT2; DGAT1B; PITPNB; SLC44A5B; CHKB; AWAT1; PEMT

    CPNE1 has several biochemical functions, for example, NF-kappaB binding, calcium ion binding, calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPNE1 itself. We selected most functions CPNE1 had, and list some proteins which have the same functions with CPNE1. You can find most of the proteins on our site.

    Function Related Protein
    NF-kappaB binding COMMD6; SNAI1A; PSMA6; TAF4B; RELA; HDAC3; HDAC1; AP1S2; CDK5RAP3; BCL10
    calcium ion binding FSTL1; PEF1; PCDH2G16; PCDH2G8; SYT4; DLK2; LTBP1; MYL1; FKBP14; RHBDL3
    calcium-dependent phospholipid binding SYT5A; DOC2B; ANXA10; SYT15; PLA2G4B; CPNE3; SYT9; SYT3; SYTL2; SYTL3
    endopeptidase activity PSMA4; KLK1B3; TPP1; REN2; PCSK6; KLK1B1; Ren1; PSMB8F; MMP9; KLK1B26
    phosphatidylserine binding SCARB1; SDPR; SYT4; ANXA9; SCIN; OSBPL5; GAP43; OSBPL8; GAS6; ANXA13
    protein binding EFCAB11; NDE1; AMY1A; SYMPK; SNRPB2; ACVR1B; NUDCD2; MED25; CHAC1; TTC6
    protein homodimerization activity CHMP3; TYMS; FZD1; TGFB1; HELT; NR0B1; MTERFD3; PFKM; GRIK2; BMP4
    transporter activity CRABP2B; LCN12; MIPB; SLC23A2; ATP6V0E1; MUP17; SLC37A4B; SLC22A13; RBP2A; ABCF2

    CPNE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPNE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPNE1.

    YWHAZ; UIMC1; BUB3; STK3; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; pi3p; FN1; ARRB2

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