cpne6
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  • Official Full Name
  • copine VI (neuronal)
  • Background
  • This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.
  • Synonyms
  • CPNE6; copine VI (neuronal); copine-6; Copine 6; Copine VI; Copine6; CopineVI; CPNE6_HUMAN; N copine; N-copine; Neuronal copine; Neuronal-copine; OTTHUMP00000027965
Cat.#:CPNE6-1802HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CPNE6 Protein, GST-tagged
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Cat.#:CPNE6-3311HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CPNE6 Protein, MYC/DDK-tagged
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Cat.#:CPNE6-3851MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CPNE6 Protein
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Cat.#:CPNE6-196HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CPNE6 lysate
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Involved Pathway

CPNE6 involved in several pathways and played different roles in them. We selected most pathways CPNE6 participated on our site, such as Glycerophospholipid biosynthesis, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPNE6 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycerophospholipid biosynthesis
CDS1; PNPLA8; PLB1; PEMT; AGPAT2; GPAT2; PTPMT1; PLD6; PHOSPHO1; CHKA
Metabolism
FA2H; BRSK2; LYRM4; SYT5; SLC26A1; APOA4B.1; NDUFAF6; PDP2; CPTP; MED18
Metabolism of lipids and lipoproteins
LMF2; CHAT; GLTPA; AKR1B15; CYP2N13; ACOT11B; MED6; ALOX5AP; SLC27A2; ABHD4
Phospholipid metabolism
CHKA; CPNE3; CPNE1; AWAT1; FIG4; PLBD1; PTPMT1; CEPT1A; SACM1LB; ABHD4

Protein Function

CPNE6 has several biochemical functions, for example, calcium ion binding, phosphatidylserine binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPNE6 itself. We selected most functions CPNE6 had, and list some proteins which have the same functions with CPNE6. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein JAG1A; S100A12; C1RA; DCHS1; PCDH1A3; NINL; CDH2; OCM; KCNIP3A; LPCAT2
Function phosphatidylserine binding
Related Protein SDPR; GAP43; OSBPL5; CPNE6; RASGRP1; AXL; SCARB1; ANXA13; SCIN; JPH2
Function protein binding
Related Protein EXOC4; NDOR1; UNC119B; HSPA1B; PPP2R3A; NDFIP1; ABCB9; RPRM; CLEC1B; ITGB1BP2
Function transporter activity
Related Protein SLC5A12; ABCA5; MUP17; AP3S1; HIATL2; AQP3B; FABP7; PTGDSB; CSN2; TMEM184C

Interacting Protein

CPNE6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPNE6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPNE6.
MEOX2; TTR; TK1; ANXA7; CDKN1A; PIN1; GRB7; MAPK11; SMN1; LAMTOR3; AK5